A-to-I editing of COG3 mRNA in bowhead muscle, kidney, liver, optical nerve and retina.
The adenosine (*) in the ATT codon encoding I635 is subject to A-to-I editing in COG3 mRNA from all tissues analyzed (ATT = Ile to GTT = Val). In addition, the adenosine in the third position in the GAA (634) codon is only edited in liver (+). The unedited GAA codon encodes a Glu residue, as does th...
Main Authors: | , |
---|---|
Format: | Other Non-Article Part of Journal/Newspaper |
Language: | unknown |
Published: |
2021
|
Subjects: | |
Online Access: | https://doi.org/10.1371/journal.pone.0260081.s001 |
id |
ftsmithonian:oai:figshare.com:article/17154970 |
---|---|
record_format |
openpolar |
spelling |
ftsmithonian:oai:figshare.com:article/17154970 2023-05-15T15:45:59+02:00 A-to-I editing of COG3 mRNA in bowhead muscle, kidney, liver, optical nerve and retina. Knud Larsen (35577) Mads Peter Heide-Jørgensen (7869812) 2021-12-09T18:37:57Z https://doi.org/10.1371/journal.pone.0260081.s001 unknown https://figshare.com/articles/journal_contribution/A-to-I_editing_of_COG3_mRNA_in_bowhead_muscle_kidney_liver_optical_nerve_and_retina_/17154970 doi:10.1371/journal.pone.0260081.s001 CC BY 4.0 CC-BY Biochemistry Microbiology Genetics Molecular Biology Evolutionary Biology Ecology Inorganic Chemistry Mental Health Infectious Diseases Virology Computational Biology two shark species proteomic sequence variation recoding &# 8217 specific adenosine deaminase neil1 242 codon adar2 &# 8211 novel editing site novel editing sites pig </ p bowhead neil1 mrnas recoding sites &# 8216 editing site two adenosines position 242 sites results selected mrnas regulatory sequence eef1a mrnas human neil1 editing mediated editing events differential editing rna sequence various tissues transcriptional process synonymous substitutions present studies porcine homologues nucleotide changes nearly 99 five adenosines common type coding sequences bowhead whales bowhead whale Text Journal contribution 2021 ftsmithonian https://doi.org/10.1371/journal.pone.0260081.s001 2021-12-19T19:46:38Z The adenosine (*) in the ATT codon encoding I635 is subject to A-to-I editing in COG3 mRNA from all tissues analyzed (ATT = Ile to GTT = Val). In addition, the adenosine in the third position in the GAA (634) codon is only edited in liver (+). The unedited GAA codon encodes a Glu residue, as does the edited GAG codon. In addition, we also found editing in codon 621 (GA A ) marked by **. This editing is not recoding. R = A/G. (DOCX) Other Non-Article Part of Journal/Newspaper bowhead whale Unknown |
institution |
Open Polar |
collection |
Unknown |
op_collection_id |
ftsmithonian |
language |
unknown |
topic |
Biochemistry Microbiology Genetics Molecular Biology Evolutionary Biology Ecology Inorganic Chemistry Mental Health Infectious Diseases Virology Computational Biology two shark species proteomic sequence variation recoding &# 8217 specific adenosine deaminase neil1 242 codon adar2 &# 8211 novel editing site novel editing sites pig </ p bowhead neil1 mrnas recoding sites &# 8216 editing site two adenosines position 242 sites results selected mrnas regulatory sequence eef1a mrnas human neil1 editing mediated editing events differential editing rna sequence various tissues transcriptional process synonymous substitutions present studies porcine homologues nucleotide changes nearly 99 five adenosines common type coding sequences bowhead whales bowhead whale |
spellingShingle |
Biochemistry Microbiology Genetics Molecular Biology Evolutionary Biology Ecology Inorganic Chemistry Mental Health Infectious Diseases Virology Computational Biology two shark species proteomic sequence variation recoding &# 8217 specific adenosine deaminase neil1 242 codon adar2 &# 8211 novel editing site novel editing sites pig </ p bowhead neil1 mrnas recoding sites &# 8216 editing site two adenosines position 242 sites results selected mrnas regulatory sequence eef1a mrnas human neil1 editing mediated editing events differential editing rna sequence various tissues transcriptional process synonymous substitutions present studies porcine homologues nucleotide changes nearly 99 five adenosines common type coding sequences bowhead whales bowhead whale Knud Larsen (35577) Mads Peter Heide-Jørgensen (7869812) A-to-I editing of COG3 mRNA in bowhead muscle, kidney, liver, optical nerve and retina. |
topic_facet |
Biochemistry Microbiology Genetics Molecular Biology Evolutionary Biology Ecology Inorganic Chemistry Mental Health Infectious Diseases Virology Computational Biology two shark species proteomic sequence variation recoding &# 8217 specific adenosine deaminase neil1 242 codon adar2 &# 8211 novel editing site novel editing sites pig </ p bowhead neil1 mrnas recoding sites &# 8216 editing site two adenosines position 242 sites results selected mrnas regulatory sequence eef1a mrnas human neil1 editing mediated editing events differential editing rna sequence various tissues transcriptional process synonymous substitutions present studies porcine homologues nucleotide changes nearly 99 five adenosines common type coding sequences bowhead whales bowhead whale |
description |
The adenosine (*) in the ATT codon encoding I635 is subject to A-to-I editing in COG3 mRNA from all tissues analyzed (ATT = Ile to GTT = Val). In addition, the adenosine in the third position in the GAA (634) codon is only edited in liver (+). The unedited GAA codon encodes a Glu residue, as does the edited GAG codon. In addition, we also found editing in codon 621 (GA A ) marked by **. This editing is not recoding. R = A/G. (DOCX) |
format |
Other Non-Article Part of Journal/Newspaper |
author |
Knud Larsen (35577) Mads Peter Heide-Jørgensen (7869812) |
author_facet |
Knud Larsen (35577) Mads Peter Heide-Jørgensen (7869812) |
author_sort |
Knud Larsen (35577) |
title |
A-to-I editing of COG3 mRNA in bowhead muscle, kidney, liver, optical nerve and retina. |
title_short |
A-to-I editing of COG3 mRNA in bowhead muscle, kidney, liver, optical nerve and retina. |
title_full |
A-to-I editing of COG3 mRNA in bowhead muscle, kidney, liver, optical nerve and retina. |
title_fullStr |
A-to-I editing of COG3 mRNA in bowhead muscle, kidney, liver, optical nerve and retina. |
title_full_unstemmed |
A-to-I editing of COG3 mRNA in bowhead muscle, kidney, liver, optical nerve and retina. |
title_sort |
a-to-i editing of cog3 mrna in bowhead muscle, kidney, liver, optical nerve and retina. |
publishDate |
2021 |
url |
https://doi.org/10.1371/journal.pone.0260081.s001 |
genre |
bowhead whale |
genre_facet |
bowhead whale |
op_relation |
https://figshare.com/articles/journal_contribution/A-to-I_editing_of_COG3_mRNA_in_bowhead_muscle_kidney_liver_optical_nerve_and_retina_/17154970 doi:10.1371/journal.pone.0260081.s001 |
op_rights |
CC BY 4.0 |
op_rightsnorm |
CC-BY |
op_doi |
https://doi.org/10.1371/journal.pone.0260081.s001 |
_version_ |
1766380646821789696 |