μCT reveals craniofacial phenotypes in adult wild-type and nkx3 . 2 uu2803/uu2803 zebrafish.
( A, B ) lateral view of wild-type and nkx3 . 2 mutant zebrafish at 90 dpf. ( C, D, E ) lateral view of the head of wild-type with closed mouth (CM), wild-type with artificially open mouth (AOM), and nkx3 . 2 mutant. ( F, G, H ) Anterior view of wild-type with CM, wild-type with AOM, and nkx3 . 2 mu...
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ftsmithonian:oai:figshare.com:article/15444116 2023-05-15T15:15:28+02:00 μCT reveals craniofacial phenotypes in adult wild-type and nkx3 . 2 uu2803/uu2803 zebrafish. Laura Waldmann (9089450) Jake Leyhr (5354375) Hanqing Zhang (2628763) Caroline Öhman-Mägi (8878487) Amin Allalou (7066343) Tatjana Haitina (76933) 2021-08-19T17:32:19Z https://doi.org/10.1371/journal.pone.0255953.g006 unknown https://figshare.com/articles/figure/_CT_reveals_craniofacial_phenotypes_in_adult_wild-type_and_i_nkx3_i_i_2_i_sup_uu2803_uu2803_sup_zebrafish_/15444116 doi:10.1371/journal.pone.0255953.g006 CC BY 4.0 CC-BY Medicine Genetics Molecular Biology Biotechnology Ecology Developmental Biology Hematology Infectious Diseases Environmental Sciences not elsewhere classified Biological Sciences not elsewhere classified function nkx 3 role phenotype zebrafish transcription factor Nkx 3.2 CRISPR chondrocyte maturation inhibitor Previous Nkx 3 gene Image Figure 2021 ftsmithonian https://doi.org/10.1371/journal.pone.0255953.g006 2021-12-20T04:00:11Z ( A, B ) lateral view of wild-type and nkx3 . 2 mutant zebrafish at 90 dpf. ( C, D, E ) lateral view of the head of wild-type with closed mouth (CM), wild-type with artificially open mouth (AOM), and nkx3 . 2 mutant. ( F, G, H ) Anterior view of wild-type with CM, wild-type with AOM, and nkx3 . 2 mutant. ( I, J, K ) ventral view of isolated wild-type dentary (CM), wild-type dentary (AOM), and nkx3 . 2 mutant dentary. ( L, M, N ) Virtual thin sections (60μm thick, averaged) through the symphysis of the dentaries displayed in I, J, K , respectively. The measurements in mm refer to standard length (SL). Asterisks in ( B , E ) indicate the fixed open mouth phenotype caused by fused jaw joint. The arrowhead in ( E ) indicates the downturned ceratohyal phenotype relative to ( D ). Angles in ( I , J ) show the flexibility of the symphysis in wild-types, the arrow in K and N indicates the thickened and deformed symphysis phenotype in nkx3 . 2 mutants. Colour scheme: Red–lower jaw; dark blue–infraorbitals; dark green–ceratohyal and anal fin; blue–basihyal; lilac–branchial arches; dark purple–supraoccipital; lime green–exoccipital and basioccipital; yellow–all remaining craniofacial bones; cyan–cleithrum and pectoral fins, arctic blue–Weberian apparatus; blue violet–vertebrae; green–pelvic fins; bronze–dorsal fin; orange–caudal fin vertebrae and hypurals; magenta–caudal fin rays. AA–anguloarticular, AF–anal fin, BH–basihyal, CF–caudal fin, CH–ceratohyal, DF–dorsal fin, DT–dentary, io3 –infraorbital 3, jj–jaw joint, le–lateral ethmoid, mx–maxilla, O–occipital region, PCF–pectoral fin, pmx–premaxilla, PVF–pelvic fin, QT–quadrate, WA–Weberian apparatus. Scale bars: 5mm ( A , B ), 1mm ( C - N ). Still Image Arctic Unknown Arctic |
institution |
Open Polar |
collection |
Unknown |
op_collection_id |
ftsmithonian |
language |
unknown |
topic |
Medicine Genetics Molecular Biology Biotechnology Ecology Developmental Biology Hematology Infectious Diseases Environmental Sciences not elsewhere classified Biological Sciences not elsewhere classified function nkx 3 role phenotype zebrafish transcription factor Nkx 3.2 CRISPR chondrocyte maturation inhibitor Previous Nkx 3 gene |
spellingShingle |
Medicine Genetics Molecular Biology Biotechnology Ecology Developmental Biology Hematology Infectious Diseases Environmental Sciences not elsewhere classified Biological Sciences not elsewhere classified function nkx 3 role phenotype zebrafish transcription factor Nkx 3.2 CRISPR chondrocyte maturation inhibitor Previous Nkx 3 gene Laura Waldmann (9089450) Jake Leyhr (5354375) Hanqing Zhang (2628763) Caroline Öhman-Mägi (8878487) Amin Allalou (7066343) Tatjana Haitina (76933) μCT reveals craniofacial phenotypes in adult wild-type and nkx3 . 2 uu2803/uu2803 zebrafish. |
topic_facet |
Medicine Genetics Molecular Biology Biotechnology Ecology Developmental Biology Hematology Infectious Diseases Environmental Sciences not elsewhere classified Biological Sciences not elsewhere classified function nkx 3 role phenotype zebrafish transcription factor Nkx 3.2 CRISPR chondrocyte maturation inhibitor Previous Nkx 3 gene |
description |
( A, B ) lateral view of wild-type and nkx3 . 2 mutant zebrafish at 90 dpf. ( C, D, E ) lateral view of the head of wild-type with closed mouth (CM), wild-type with artificially open mouth (AOM), and nkx3 . 2 mutant. ( F, G, H ) Anterior view of wild-type with CM, wild-type with AOM, and nkx3 . 2 mutant. ( I, J, K ) ventral view of isolated wild-type dentary (CM), wild-type dentary (AOM), and nkx3 . 2 mutant dentary. ( L, M, N ) Virtual thin sections (60μm thick, averaged) through the symphysis of the dentaries displayed in I, J, K , respectively. The measurements in mm refer to standard length (SL). Asterisks in ( B , E ) indicate the fixed open mouth phenotype caused by fused jaw joint. The arrowhead in ( E ) indicates the downturned ceratohyal phenotype relative to ( D ). Angles in ( I , J ) show the flexibility of the symphysis in wild-types, the arrow in K and N indicates the thickened and deformed symphysis phenotype in nkx3 . 2 mutants. Colour scheme: Red–lower jaw; dark blue–infraorbitals; dark green–ceratohyal and anal fin; blue–basihyal; lilac–branchial arches; dark purple–supraoccipital; lime green–exoccipital and basioccipital; yellow–all remaining craniofacial bones; cyan–cleithrum and pectoral fins, arctic blue–Weberian apparatus; blue violet–vertebrae; green–pelvic fins; bronze–dorsal fin; orange–caudal fin vertebrae and hypurals; magenta–caudal fin rays. AA–anguloarticular, AF–anal fin, BH–basihyal, CF–caudal fin, CH–ceratohyal, DF–dorsal fin, DT–dentary, io3 –infraorbital 3, jj–jaw joint, le–lateral ethmoid, mx–maxilla, O–occipital region, PCF–pectoral fin, pmx–premaxilla, PVF–pelvic fin, QT–quadrate, WA–Weberian apparatus. Scale bars: 5mm ( A , B ), 1mm ( C - N ). |
format |
Still Image |
author |
Laura Waldmann (9089450) Jake Leyhr (5354375) Hanqing Zhang (2628763) Caroline Öhman-Mägi (8878487) Amin Allalou (7066343) Tatjana Haitina (76933) |
author_facet |
Laura Waldmann (9089450) Jake Leyhr (5354375) Hanqing Zhang (2628763) Caroline Öhman-Mägi (8878487) Amin Allalou (7066343) Tatjana Haitina (76933) |
author_sort |
Laura Waldmann (9089450) |
title |
μCT reveals craniofacial phenotypes in adult wild-type and nkx3 . 2 uu2803/uu2803 zebrafish. |
title_short |
μCT reveals craniofacial phenotypes in adult wild-type and nkx3 . 2 uu2803/uu2803 zebrafish. |
title_full |
μCT reveals craniofacial phenotypes in adult wild-type and nkx3 . 2 uu2803/uu2803 zebrafish. |
title_fullStr |
μCT reveals craniofacial phenotypes in adult wild-type and nkx3 . 2 uu2803/uu2803 zebrafish. |
title_full_unstemmed |
μCT reveals craniofacial phenotypes in adult wild-type and nkx3 . 2 uu2803/uu2803 zebrafish. |
title_sort |
μct reveals craniofacial phenotypes in adult wild-type and nkx3 . 2 uu2803/uu2803 zebrafish. |
publishDate |
2021 |
url |
https://doi.org/10.1371/journal.pone.0255953.g006 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_relation |
https://figshare.com/articles/figure/_CT_reveals_craniofacial_phenotypes_in_adult_wild-type_and_i_nkx3_i_i_2_i_sup_uu2803_uu2803_sup_zebrafish_/15444116 doi:10.1371/journal.pone.0255953.g006 |
op_rights |
CC BY 4.0 |
op_rightsnorm |
CC-BY |
op_doi |
https://doi.org/10.1371/journal.pone.0255953.g006 |
_version_ |
1766345840415211520 |