Local Contrasts in Concentration of Ambient Particulate Air Pollution (PM2.5) and Incidence of Alzheimer's Disease and Dementia : Results from the Betula Cohort in Northern Sweden Comment
Exposure to fine particulate air pollution (PM2.5) is emerging as a risk factor for Alzheimer's disease (AD), but existing studies are still limited and heterogeneous. We have previously studied the association between dementia (AD and vascular dementia) and PM2.5 stemming from vehicle exhaust...
Published in: | Journal of Alzheimer's Disease |
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Online Access: | http://urn.kb.se/resolve?urn=urn:nbn:se:smhi:diva-6111 https://doi.org/10.3233/JAD-201538 |
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ftsmhi:oai:DiVA.org:smhi-6111 2023-05-15T17:44:22+02:00 Local Contrasts in Concentration of Ambient Particulate Air Pollution (PM2.5) and Incidence of Alzheimer's Disease and Dementia : Results from the Betula Cohort in Northern Sweden Comment Astrom, Daniel Oudin Adolfsson, Rolf Segersson, David Forsberg, Bertil Oudin, Anna 2021 application/pdf http://urn.kb.se/resolve?urn=urn:nbn:se:smhi:diva-6111 https://doi.org/10.3233/JAD-201538 eng eng Luftmiljö Journal of Alzheimer's Disease, 1387-2877, 2021, 81:1, s. 83-85 http://urn.kb.se/resolve?urn=urn:nbn:se:smhi:diva-6111 doi:10.3233/JAD-201538 PMID 33749652 ISI:000648474400006 info:eu-repo/semantics/openAccess Meteorology and Atmospheric Sciences Meteorologi och atmosfärforskning Article in journal info:eu-repo/semantics/article text 2021 ftsmhi https://doi.org/10.3233/JAD-201538 2022-12-09T10:06:17Z Exposure to fine particulate air pollution (PM2.5) is emerging as a risk factor for Alzheimer's disease (AD), but existing studies are still limited and heterogeneous. We have previously studied the association between dementia (AD and vascular dementia) and PM2.5 stemming from vehicle exhaust and wood-smoke in the Betula cohort in Northern Sweden. The aim of this commentary is to estimate the association between total PM2.5 and dementia in the Betula cohort, which is more relevant to include in future meta-estimates than the source-specific estimates. The hazard ratio for incident dementia associated with a 1 mu g/m(3) increase in local PM2.5 was 1.38 (95% confidence interval: 0.99 - 1.92). The interpretation of our results is that they indicate an association between local contrasts in concentration of PM2.5 at the residential address and incidence of dementia in a low-level setting. Article in Journal/Newspaper Northern Sweden SMHI (Swedish Meteorological and Hydrological Institute): Vetenskapliga Publikationer (DiVA) Journal of Alzheimer's Disease 81 1 83 85 |
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SMHI (Swedish Meteorological and Hydrological Institute): Vetenskapliga Publikationer (DiVA) |
op_collection_id |
ftsmhi |
language |
English |
topic |
Meteorology and Atmospheric Sciences Meteorologi och atmosfärforskning |
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Meteorology and Atmospheric Sciences Meteorologi och atmosfärforskning Astrom, Daniel Oudin Adolfsson, Rolf Segersson, David Forsberg, Bertil Oudin, Anna Local Contrasts in Concentration of Ambient Particulate Air Pollution (PM2.5) and Incidence of Alzheimer's Disease and Dementia : Results from the Betula Cohort in Northern Sweden Comment |
topic_facet |
Meteorology and Atmospheric Sciences Meteorologi och atmosfärforskning |
description |
Exposure to fine particulate air pollution (PM2.5) is emerging as a risk factor for Alzheimer's disease (AD), but existing studies are still limited and heterogeneous. We have previously studied the association between dementia (AD and vascular dementia) and PM2.5 stemming from vehicle exhaust and wood-smoke in the Betula cohort in Northern Sweden. The aim of this commentary is to estimate the association between total PM2.5 and dementia in the Betula cohort, which is more relevant to include in future meta-estimates than the source-specific estimates. The hazard ratio for incident dementia associated with a 1 mu g/m(3) increase in local PM2.5 was 1.38 (95% confidence interval: 0.99 - 1.92). The interpretation of our results is that they indicate an association between local contrasts in concentration of PM2.5 at the residential address and incidence of dementia in a low-level setting. |
format |
Article in Journal/Newspaper |
author |
Astrom, Daniel Oudin Adolfsson, Rolf Segersson, David Forsberg, Bertil Oudin, Anna |
author_facet |
Astrom, Daniel Oudin Adolfsson, Rolf Segersson, David Forsberg, Bertil Oudin, Anna |
author_sort |
Astrom, Daniel Oudin |
title |
Local Contrasts in Concentration of Ambient Particulate Air Pollution (PM2.5) and Incidence of Alzheimer's Disease and Dementia : Results from the Betula Cohort in Northern Sweden Comment |
title_short |
Local Contrasts in Concentration of Ambient Particulate Air Pollution (PM2.5) and Incidence of Alzheimer's Disease and Dementia : Results from the Betula Cohort in Northern Sweden Comment |
title_full |
Local Contrasts in Concentration of Ambient Particulate Air Pollution (PM2.5) and Incidence of Alzheimer's Disease and Dementia : Results from the Betula Cohort in Northern Sweden Comment |
title_fullStr |
Local Contrasts in Concentration of Ambient Particulate Air Pollution (PM2.5) and Incidence of Alzheimer's Disease and Dementia : Results from the Betula Cohort in Northern Sweden Comment |
title_full_unstemmed |
Local Contrasts in Concentration of Ambient Particulate Air Pollution (PM2.5) and Incidence of Alzheimer's Disease and Dementia : Results from the Betula Cohort in Northern Sweden Comment |
title_sort |
local contrasts in concentration of ambient particulate air pollution (pm2.5) and incidence of alzheimer's disease and dementia : results from the betula cohort in northern sweden comment |
publisher |
Luftmiljö |
publishDate |
2021 |
url |
http://urn.kb.se/resolve?urn=urn:nbn:se:smhi:diva-6111 https://doi.org/10.3233/JAD-201538 |
genre |
Northern Sweden |
genre_facet |
Northern Sweden |
op_relation |
Journal of Alzheimer's Disease, 1387-2877, 2021, 81:1, s. 83-85 http://urn.kb.se/resolve?urn=urn:nbn:se:smhi:diva-6111 doi:10.3233/JAD-201538 PMID 33749652 ISI:000648474400006 |
op_rights |
info:eu-repo/semantics/openAccess |
op_doi |
https://doi.org/10.3233/JAD-201538 |
container_title |
Journal of Alzheimer's Disease |
container_volume |
81 |
container_issue |
1 |
container_start_page |
83 |
op_container_end_page |
85 |
_version_ |
1766146574963965952 |