Premutations in C9ORF72 and FMR1 in Iceland

• Main Author: Ástrós Skúladóttir 1991-
• Other Authors: Háskóli Íslands
• Format: Thesis
• Language: English
• Published: 2019
• Subjects: Lífvísindi; Genamengi; Gen; Arfgengi; Stökkbreytingar; Raðgreining; Nitur; Rannsóknir; Svæði; Iceland
• Online Access: http://hdl.handle.net/1946/32162

Modern sequencing technology has been instrumental in determining the sequence of DNA. However, there are regions within the genome that cannot be sequenced using traditional methods. Repetitive DNA sequences such as GC-rich repeat expansions can alter gene expression and confer risk of or cause dis...