High frequency of allelic imbalance at chromosome region 16q22-23 in human breast cancer: Correlation with high PgR and low S phase

• Main Authors: Sigurður Ingvarsson 1956-, Sigurlaug Skírnisdóttir 1970-, Guðný Eiríksdóttir 1950-, Trausti Baldursson 1956-, Rósa Björk Barkardóttir 1958-, Valgarður Egilsson 1940-
• Other Authors: Háskóli Íslands
• Format: Article in Journal/Newspaper
• Language: English
• Published: 1995
• Subjects: Long Arm; Iceland
• Online Access: http://hdl.handle.net/1946/20692

The loss of genetic material from a specific chromosome region in tumors suggests the presence of tumor-suppressor genes. Loss of heterozygosity (LOH) or allelic imbalance (Al) on the long arm of chromosome 16 is a known event in sporadic breast cancer. To locate the commonly deleted regions, and th...