The genetic landscape of familial breast cancer in Iceland

In Iceland a rare founder mutation has been detected in BRCA1, and a frequent one in BRCA2. An extensive analysis on somatic changes and gene expression in tumours of the BRCA2 999del5 founder-mutation carriers has been made. Population-based studies have been performed on a large number of availabl...

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Bibliographic Details
Main Author: Sigurður Ingvarsson 1956-
Other Authors: Háskóli Íslands
Format: Article in Journal/Newspaper
Language:English
Published: 2014
Subjects:
Brjóstakrabbamein
Iceland
Online Access:http://hdl.handle.net/1946/20587
id ftskemman:oai:skemman.is:1946/20587
record_format openpolar
spelling ftskemman:oai:skemman.is:1946/20587 2023-05-15T16:45:06+02:00 The genetic landscape of familial breast cancer in Iceland Sigurður Ingvarsson 1956- Háskóli Íslands 2014-10 application/pdf http://hdl.handle.net/1946/20587 en eng https://www.researchgate.net/publication/266794615_The_genetic_landscape_of_familial_breast_cancer_in_Iceland http://apps.webofknowledge.com/full_record.do?product=UA&search_mode=GeneralSearch&qid=1&SID=V2cjQ5XBa9jtrV2j3DF&page=1&doc=2 http://ar.iiarjournals.org/content/34/10/5761 Anticancer Research 2014 (34), 5962-5966 0250-7005 http://hdl.handle.net/1946/20587 Brjóstakrabbamein Article 2014 ftskemman 2022-12-11T06:52:33Z In Iceland a rare founder mutation has been detected in BRCA1, and a frequent one in BRCA2. An extensive analysis on somatic changes and gene expression in tumours of the BRCA2 999del5 founder-mutation carriers has been made. Population-based studies have been performed on a large number of available carriers, regarding penetrance, cancer risk, phenotype, clinicopathology, genetic modifiers and influence from the environment. Article in Journal/Newspaper Iceland Skemman (Iceland)
institution Open Polar
collection Skemman (Iceland)
op_collection_id ftskemman
language English
topic Brjóstakrabbamein
spellingShingle Brjóstakrabbamein
Sigurður Ingvarsson 1956-
The genetic landscape of familial breast cancer in Iceland
topic_facet Brjóstakrabbamein
description In Iceland a rare founder mutation has been detected in BRCA1, and a frequent one in BRCA2. An extensive analysis on somatic changes and gene expression in tumours of the BRCA2 999del5 founder-mutation carriers has been made. Population-based studies have been performed on a large number of available carriers, regarding penetrance, cancer risk, phenotype, clinicopathology, genetic modifiers and influence from the environment.
author2 Háskóli Íslands
format Article in Journal/Newspaper
author Sigurður Ingvarsson 1956-
author_facet Sigurður Ingvarsson 1956-
author_sort Sigurður Ingvarsson 1956-
title The genetic landscape of familial breast cancer in Iceland
title_short The genetic landscape of familial breast cancer in Iceland
title_full The genetic landscape of familial breast cancer in Iceland
title_fullStr The genetic landscape of familial breast cancer in Iceland
title_full_unstemmed The genetic landscape of familial breast cancer in Iceland
title_sort genetic landscape of familial breast cancer in iceland
publishDate 2014
url http://hdl.handle.net/1946/20587
genre Iceland
genre_facet Iceland
op_relation https://www.researchgate.net/publication/266794615_The_genetic_landscape_of_familial_breast_cancer_in_Iceland
http://apps.webofknowledge.com/full_record.do?product=UA&search_mode=GeneralSearch&qid=1&SID=V2cjQ5XBa9jtrV2j3DF&page=1&doc=2
http://ar.iiarjournals.org/content/34/10/5761
Anticancer Research 2014 (34), 5962-5966
0250-7005
http://hdl.handle.net/1946/20587
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