Missed, Not Missing: Phylogenomic Evidence for the Existence of Avian FoxP3

• Main Authors: Denyer, M P, Pinheiro, D Y, Garden, O A, Shepherd, A J
• Format: Article in Journal/Newspaper
• Language: English
• Published: 2016
• Subjects: Parus; Falco peregrinus; peregrine falcon
• Online Access: https://researchonline.rvc.ac.uk/id/eprint/10111/; https://researchonline.rvc.ac.uk/id/eprint/10111/1/10111.pdf

The Forkhead box transcription factor FoxP3 is pivotal to the development and function of regulatory T cells (Tregs), which make a major contribution to peripheral tolerance. FoxP3 is believed to perform a regulatory role in all the vertebrate species in which it has been detected. The prevailing vi...