Oils Derived from GM Crops as Sustainable Solutions to the Supply of Long-Chain Omega-3 for On-Growing Atlantic Bluefin Tuna (Thunnus thynnus L.)
Recently Camelina sativa, has been genetically modified to produce oils rich in omega-3 (n-3) long-chain polyunsaturated fatty acids (LC-PUFA), EPA (eicosapentaenoic acid) and EPA + DHA (docosahexaenoic acid). The aim of this study was to test the feasibility of using these novel sources of de novo...
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MDPI
2022
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Online Access: | https://repository.rothamsted.ac.uk/item/98v2y/oils-derived-from-gm-crops-as-sustainable-solutions-to-the-supply-of-long-chain-omega-3-for-on-growing-atlantic-bluefin-tuna-thunnus-thynnus-l https://repository.rothamsted.ac.uk/download/b1c24ae677beb413a3be969b7f3127e5f70ed30277b18e643fb8880fe8619035/5401066/betancor%20et%20al%202022%20fishes-07-00366.pdf https://doi.org/10.3390/fishes7060366 |
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ftrothamstedres:oai:repository.rothamsted.ac.uk:98v2y 2023-05-15T18:09:57+02:00 Oils Derived from GM Crops as Sustainable Solutions to the Supply of Long-Chain Omega-3 for On-Growing Atlantic Bluefin Tuna (Thunnus thynnus L.) Betancor, M. B. Sprague, M. Gonzalez-Silvera, D. Ortega, A. De la Gandara, F. Gong, X. Napier, J. A. Tocher, D. R. Mourente, G. 2022 application/pdf https://repository.rothamsted.ac.uk/item/98v2y/oils-derived-from-gm-crops-as-sustainable-solutions-to-the-supply-of-long-chain-omega-3-for-on-growing-atlantic-bluefin-tuna-thunnus-thynnus-l https://repository.rothamsted.ac.uk/download/b1c24ae677beb413a3be969b7f3127e5f70ed30277b18e643fb8880fe8619035/5401066/betancor%20et%20al%202022%20fishes-07-00366.pdf https://doi.org/10.3390/fishes7060366 unknown MDPI https://repository.rothamsted.ac.uk/download/b1c24ae677beb413a3be969b7f3127e5f70ed30277b18e643fb8880fe8619035/5401066/betancor%20et%20al%202022%20fishes-07-00366.pdf https://doi.org/10.3390/fishes7060366 Betancor, M. B., Sprague, M., Gonzalez-Silvera, D., Ortega, A., De la Gandara, F., Gong, X., Napier, J. A., Tocher, D. R. and Mourente, G. 2022. Oils Derived from GM Crops as Sustainable Solutions to the Supply of Long-Chain Omega-3 for On-Growing Atlantic Bluefin Tuna (Thunnus thynnus L.). Fishes. 7 (6), p. 366. https://doi.org/10.3390/fishes7060366 Atlantic bluefin tuna GM Camelina Dietary oils Sustainable feeds Hepatic lipid metabolism Polyunsaturated fatty-acids Transgenic camelina-sativa Bream Sparus-Aurata Salmon Salmo-Salar Dietary Docosahexaenoic Acid Fish-Oil Gene-Expression Growth-Performance Digestive Enzymes Larvae journal-article 2022 ftrothamstedres https://doi.org/10.3390/fishes7060366 2023-01-30T18:26:28Z Recently Camelina sativa, has been genetically modified to produce oils rich in omega-3 (n-3) long-chain polyunsaturated fatty acids (LC-PUFA), EPA (eicosapentaenoic acid) and EPA + DHA (docosahexaenoic acid). The aim of this study was to test the feasibility of using these novel sources of de novo EPA and EPA + DHA as substitutes for marine oil in feeds for juvenile Atlantic Bluefin tuna (ABT). The results showed the oils were practical sources of n-3 LC-PUFA which could potentially replace fish oil (FO) in feeds for ABT juveniles. Fish fed the test diets (ECO, EPA alone and DCO, EPA + DHA) displayed good growth performance, survival and feed utilisation approaching that of ABT fed the reference diet (MGK) containing marine fish oil with the rank order being MGK > DCO > ECO. The test diets showed positive effects, upregulating the expression of genes of major nuclear receptors and those of lipid metabolism including digestion, LC-PUFA synthesis and antioxidant pathways. The results indicated that the DCO feed containing both DHA and EPA performed better than the ECO feed with much lower DHA. However, feeds formulated with both these oils may still require supplementary DHA to satisfy the high requirement of ABT for this essential nutrient. Other/Unknown Material Salmo salar Rothamsted Repository (Rothamsted Research) Fishes 7 6 366 |
institution |
Open Polar |
collection |
Rothamsted Repository (Rothamsted Research) |
op_collection_id |
ftrothamstedres |
language |
unknown |
topic |
Atlantic bluefin tuna GM Camelina Dietary oils Sustainable feeds Hepatic lipid metabolism Polyunsaturated fatty-acids Transgenic camelina-sativa Bream Sparus-Aurata Salmon Salmo-Salar Dietary Docosahexaenoic Acid Fish-Oil Gene-Expression Growth-Performance Digestive Enzymes Larvae |
spellingShingle |
Atlantic bluefin tuna GM Camelina Dietary oils Sustainable feeds Hepatic lipid metabolism Polyunsaturated fatty-acids Transgenic camelina-sativa Bream Sparus-Aurata Salmon Salmo-Salar Dietary Docosahexaenoic Acid Fish-Oil Gene-Expression Growth-Performance Digestive Enzymes Larvae Betancor, M. B. Sprague, M. Gonzalez-Silvera, D. Ortega, A. De la Gandara, F. Gong, X. Napier, J. A. Tocher, D. R. Mourente, G. Oils Derived from GM Crops as Sustainable Solutions to the Supply of Long-Chain Omega-3 for On-Growing Atlantic Bluefin Tuna (Thunnus thynnus L.) |
topic_facet |
Atlantic bluefin tuna GM Camelina Dietary oils Sustainable feeds Hepatic lipid metabolism Polyunsaturated fatty-acids Transgenic camelina-sativa Bream Sparus-Aurata Salmon Salmo-Salar Dietary Docosahexaenoic Acid Fish-Oil Gene-Expression Growth-Performance Digestive Enzymes Larvae |
description |
Recently Camelina sativa, has been genetically modified to produce oils rich in omega-3 (n-3) long-chain polyunsaturated fatty acids (LC-PUFA), EPA (eicosapentaenoic acid) and EPA + DHA (docosahexaenoic acid). The aim of this study was to test the feasibility of using these novel sources of de novo EPA and EPA + DHA as substitutes for marine oil in feeds for juvenile Atlantic Bluefin tuna (ABT). The results showed the oils were practical sources of n-3 LC-PUFA which could potentially replace fish oil (FO) in feeds for ABT juveniles. Fish fed the test diets (ECO, EPA alone and DCO, EPA + DHA) displayed good growth performance, survival and feed utilisation approaching that of ABT fed the reference diet (MGK) containing marine fish oil with the rank order being MGK > DCO > ECO. The test diets showed positive effects, upregulating the expression of genes of major nuclear receptors and those of lipid metabolism including digestion, LC-PUFA synthesis and antioxidant pathways. The results indicated that the DCO feed containing both DHA and EPA performed better than the ECO feed with much lower DHA. However, feeds formulated with both these oils may still require supplementary DHA to satisfy the high requirement of ABT for this essential nutrient. |
format |
Other/Unknown Material |
author |
Betancor, M. B. Sprague, M. Gonzalez-Silvera, D. Ortega, A. De la Gandara, F. Gong, X. Napier, J. A. Tocher, D. R. Mourente, G. |
author_facet |
Betancor, M. B. Sprague, M. Gonzalez-Silvera, D. Ortega, A. De la Gandara, F. Gong, X. Napier, J. A. Tocher, D. R. Mourente, G. |
author_sort |
Betancor, M. B. |
title |
Oils Derived from GM Crops as Sustainable Solutions to the Supply of Long-Chain Omega-3 for On-Growing Atlantic Bluefin Tuna (Thunnus thynnus L.) |
title_short |
Oils Derived from GM Crops as Sustainable Solutions to the Supply of Long-Chain Omega-3 for On-Growing Atlantic Bluefin Tuna (Thunnus thynnus L.) |
title_full |
Oils Derived from GM Crops as Sustainable Solutions to the Supply of Long-Chain Omega-3 for On-Growing Atlantic Bluefin Tuna (Thunnus thynnus L.) |
title_fullStr |
Oils Derived from GM Crops as Sustainable Solutions to the Supply of Long-Chain Omega-3 for On-Growing Atlantic Bluefin Tuna (Thunnus thynnus L.) |
title_full_unstemmed |
Oils Derived from GM Crops as Sustainable Solutions to the Supply of Long-Chain Omega-3 for On-Growing Atlantic Bluefin Tuna (Thunnus thynnus L.) |
title_sort |
oils derived from gm crops as sustainable solutions to the supply of long-chain omega-3 for on-growing atlantic bluefin tuna (thunnus thynnus l.) |
publisher |
MDPI |
publishDate |
2022 |
url |
https://repository.rothamsted.ac.uk/item/98v2y/oils-derived-from-gm-crops-as-sustainable-solutions-to-the-supply-of-long-chain-omega-3-for-on-growing-atlantic-bluefin-tuna-thunnus-thynnus-l https://repository.rothamsted.ac.uk/download/b1c24ae677beb413a3be969b7f3127e5f70ed30277b18e643fb8880fe8619035/5401066/betancor%20et%20al%202022%20fishes-07-00366.pdf https://doi.org/10.3390/fishes7060366 |
genre |
Salmo salar |
genre_facet |
Salmo salar |
op_relation |
https://repository.rothamsted.ac.uk/download/b1c24ae677beb413a3be969b7f3127e5f70ed30277b18e643fb8880fe8619035/5401066/betancor%20et%20al%202022%20fishes-07-00366.pdf https://doi.org/10.3390/fishes7060366 Betancor, M. B., Sprague, M., Gonzalez-Silvera, D., Ortega, A., De la Gandara, F., Gong, X., Napier, J. A., Tocher, D. R. and Mourente, G. 2022. Oils Derived from GM Crops as Sustainable Solutions to the Supply of Long-Chain Omega-3 for On-Growing Atlantic Bluefin Tuna (Thunnus thynnus L.). Fishes. 7 (6), p. 366. https://doi.org/10.3390/fishes7060366 |
op_doi |
https://doi.org/10.3390/fishes7060366 |
container_title |
Fishes |
container_volume |
7 |
container_issue |
6 |
container_start_page |
366 |
_version_ |
1766182657045037056 |