Macrosomia, Perinatal and Infant Mortality in Cree Communities in Quebec, 1996-2010
Background: Cree births in Quebec are characterized by the highest reported prevalence of macrosomia (~35%) in the world. It is unclear whether Cree births are at greater elevated risk of perinatal and infant mortality than other First Nations relative to non-Aboriginal births in Quebec, and if macr...
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ftrepec:oai:RePEc:plo:pone00:0160766 2023-05-15T16:14:56+02:00 Macrosomia, Perinatal and Infant Mortality in Cree Communities in Quebec, 1996-2010 Lin Xiao Dan-Li Zhang Jill Torrie Nathalie Auger Nancy Gros-Louis McHugh Zhong-Cheng Luo https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0160766 https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0160766&type=printable unknown https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0160766 https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0160766&type=printable article ftrepec 2020-12-04T13:37:59Z Background: Cree births in Quebec are characterized by the highest reported prevalence of macrosomia (~35%) in the world. It is unclear whether Cree births are at greater elevated risk of perinatal and infant mortality than other First Nations relative to non-Aboriginal births in Quebec, and if macrosomia may be related. Methods: This was a population-based retrospective birth cohort study using the linked birth-infant death database for singleton births to mothers from Cree (n = 5,340), other First Nations (n = 10,810) and non-Aboriginal (n = 229,960) communities in Quebec, 1996–2010. Community type was ascertained by residential postal code and municipality name. The primary outcomes were perinatal and infant mortality. Results: Macrosomia (birth weight for gestational age >90th percentile) was substantially more frequent in Cree (38.0%) and other First Nations (21.9%) vs non-Aboriginal (9.4%) communities. Comparing Cree and other First Nations vs non-Aboriginal communities, perinatal mortality rates were 1.52 (95% confidence intervals 1.17, 1.98) and 1.34 (1.10, 1.64) times higher, and infant mortality rates 2.27 (1.71, 3.02) and 1.49 (1.16, 1.91) times higher, respectively. The risk elevations in perinatal and infant death in Cree communities attenuated after adjusting for maternal characteristics (age, education, marital status, parity), but became greater after further adjustment for birth weight (small, appropriate, or large for gestational age). Conclusions: Cree communities had greater risk elevations in perinatal and infant mortality than other First Nations relative to non-Aboriginal communities in Quebec. High prevalence of macrosomia did not explain the elevated risk of perinatal and infant mortality in Cree communities. Article in Journal/Newspaper First Nations RePEc (Research Papers in Economics) |
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Background: Cree births in Quebec are characterized by the highest reported prevalence of macrosomia (~35%) in the world. It is unclear whether Cree births are at greater elevated risk of perinatal and infant mortality than other First Nations relative to non-Aboriginal births in Quebec, and if macrosomia may be related. Methods: This was a population-based retrospective birth cohort study using the linked birth-infant death database for singleton births to mothers from Cree (n = 5,340), other First Nations (n = 10,810) and non-Aboriginal (n = 229,960) communities in Quebec, 1996–2010. Community type was ascertained by residential postal code and municipality name. The primary outcomes were perinatal and infant mortality. Results: Macrosomia (birth weight for gestational age >90th percentile) was substantially more frequent in Cree (38.0%) and other First Nations (21.9%) vs non-Aboriginal (9.4%) communities. Comparing Cree and other First Nations vs non-Aboriginal communities, perinatal mortality rates were 1.52 (95% confidence intervals 1.17, 1.98) and 1.34 (1.10, 1.64) times higher, and infant mortality rates 2.27 (1.71, 3.02) and 1.49 (1.16, 1.91) times higher, respectively. The risk elevations in perinatal and infant death in Cree communities attenuated after adjusting for maternal characteristics (age, education, marital status, parity), but became greater after further adjustment for birth weight (small, appropriate, or large for gestational age). Conclusions: Cree communities had greater risk elevations in perinatal and infant mortality than other First Nations relative to non-Aboriginal communities in Quebec. High prevalence of macrosomia did not explain the elevated risk of perinatal and infant mortality in Cree communities. |
format |
Article in Journal/Newspaper |
author |
Lin Xiao Dan-Li Zhang Jill Torrie Nathalie Auger Nancy Gros-Louis McHugh Zhong-Cheng Luo |
spellingShingle |
Lin Xiao Dan-Li Zhang Jill Torrie Nathalie Auger Nancy Gros-Louis McHugh Zhong-Cheng Luo Macrosomia, Perinatal and Infant Mortality in Cree Communities in Quebec, 1996-2010 |
author_facet |
Lin Xiao Dan-Li Zhang Jill Torrie Nathalie Auger Nancy Gros-Louis McHugh Zhong-Cheng Luo |
author_sort |
Lin Xiao |
title |
Macrosomia, Perinatal and Infant Mortality in Cree Communities in Quebec, 1996-2010 |
title_short |
Macrosomia, Perinatal and Infant Mortality in Cree Communities in Quebec, 1996-2010 |
title_full |
Macrosomia, Perinatal and Infant Mortality in Cree Communities in Quebec, 1996-2010 |
title_fullStr |
Macrosomia, Perinatal and Infant Mortality in Cree Communities in Quebec, 1996-2010 |
title_full_unstemmed |
Macrosomia, Perinatal and Infant Mortality in Cree Communities in Quebec, 1996-2010 |
title_sort |
macrosomia, perinatal and infant mortality in cree communities in quebec, 1996-2010 |
url |
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0160766 https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0160766&type=printable |
genre |
First Nations |
genre_facet |
First Nations |
op_relation |
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0160766 https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0160766&type=printable |
_version_ |
1766000670591156224 |