A genomic island linked to ecotype divergence in Atlantic cod

The genomic architecture underlying ecological divergence and ecological speciation with gene flow is still largely unknown for most organisms. One central question is whether divergence is genome-wide or localized in 'genomic mosaics' during early stages when gene flow is still pronounced...

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Published in:Molecular Ecology
Main Authors: Hemmer-Hansen, Jakob, Nielsen, Einar E, Therkildsen, Nina O, Taylor, Martin I, Ogden, Rob, Geffen, Audrey J, Bekkevold, Dorte, Helyar, Sarah, Pampoulie, Christophe, Johansen, Torild, Carvalho, Gary R
Format: Article in Journal/Newspaper
Language:English
Published: 2013
Subjects:
Online Access:https://pure.qub.ac.uk/en/publications/ec886fbd-3d29-4932-8939-2ec397b65bc1
https://doi.org/10.1111/mec.12284
https://pureadmin.qub.ac.uk/ws/files/17743931/jakob_MOL_ECOL.pdf
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spelling ftqueensubelpubl:oai:pure.qub.ac.uk/portal:publications/ec886fbd-3d29-4932-8939-2ec397b65bc1 2024-05-19T07:37:07+00:00 A genomic island linked to ecotype divergence in Atlantic cod Hemmer-Hansen, Jakob Nielsen, Einar E Therkildsen, Nina O Taylor, Martin I Ogden, Rob Geffen, Audrey J Bekkevold, Dorte Helyar, Sarah Pampoulie, Christophe Johansen, Torild Carvalho, Gary R 2013-05 application/pdf https://pure.qub.ac.uk/en/publications/ec886fbd-3d29-4932-8939-2ec397b65bc1 https://doi.org/10.1111/mec.12284 https://pureadmin.qub.ac.uk/ws/files/17743931/jakob_MOL_ECOL.pdf eng eng https://pure.qub.ac.uk/en/publications/ec886fbd-3d29-4932-8939-2ec397b65bc1 info:eu-repo/semantics/openAccess Hemmer-Hansen , J , Nielsen , E E , Therkildsen , N O , Taylor , M I , Ogden , R , Geffen , A J , Bekkevold , D , Helyar , S , Pampoulie , C , Johansen , T , FishPopTrace Consortium & Carvalho , G R 2013 , ' A genomic island linked to ecotype divergence in Atlantic cod ' , Molecular Ecology , vol. 22 , no. 10 , pp. 2653-67 . https://doi.org/10.1111/mec.12284 Animals Gadus morhua Gene Flow Genetic Variation Genetics Population Genomic Islands Genotype Population Dynamics /dk/atira/pure/sustainabledevelopmentgoals/life_below_water name=SDG 14 - Life Below Water article 2013 ftqueensubelpubl https://doi.org/10.1111/mec.12284 2024-05-02T00:21:32Z The genomic architecture underlying ecological divergence and ecological speciation with gene flow is still largely unknown for most organisms. One central question is whether divergence is genome-wide or localized in 'genomic mosaics' during early stages when gene flow is still pronounced. Empirical work has so far been limited, and the relative impacts of gene flow and natural selection on genomic patterns have not been fully explored. Here, we use ecotypes of Atlantic cod to investigate genomic patterns of diversity and population differentiation in a natural system characterized by high gene flow and large effective population sizes, properties which theoretically could restrict divergence in local genomic regions. We identify a genomic region of strong population differentiation, extending over approximately 20 cM, between pairs of migratory and stationary ecotypes examined at two different localities. Furthermore, the region is characterized by markedly reduced levels of genetic diversity in migratory ecotype samples. The results highlight the genomic region, or 'genomic island', as potentially associated with ecological divergence and suggest the involvement of a selective sweep. Finally, we also confirm earlier findings of localized genomic differentiation in three other linkage groups associated with divergence among eastern Atlantic populations. Thus, although the underlying mechanisms are still unknown, the results suggest that 'genomic mosaics' of differentiation may even be found under high levels of gene flow and that marine fishes may provide insightful model systems for studying and identifying initial targets of selection during ecological divergence. Article in Journal/Newspaper atlantic cod Gadus morhua Queen's University Belfast Research Portal Molecular Ecology 22 10 2653 2667
institution Open Polar
collection Queen's University Belfast Research Portal
op_collection_id ftqueensubelpubl
language English
topic Animals
Gadus morhua
Gene Flow
Genetic Variation
Genetics
Population
Genomic Islands
Genotype
Population Dynamics
/dk/atira/pure/sustainabledevelopmentgoals/life_below_water
name=SDG 14 - Life Below Water
spellingShingle Animals
Gadus morhua
Gene Flow
Genetic Variation
Genetics
Population
Genomic Islands
Genotype
Population Dynamics
/dk/atira/pure/sustainabledevelopmentgoals/life_below_water
name=SDG 14 - Life Below Water
Hemmer-Hansen, Jakob
Nielsen, Einar E
Therkildsen, Nina O
Taylor, Martin I
Ogden, Rob
Geffen, Audrey J
Bekkevold, Dorte
Helyar, Sarah
Pampoulie, Christophe
Johansen, Torild
Carvalho, Gary R
A genomic island linked to ecotype divergence in Atlantic cod
topic_facet Animals
Gadus morhua
Gene Flow
Genetic Variation
Genetics
Population
Genomic Islands
Genotype
Population Dynamics
/dk/atira/pure/sustainabledevelopmentgoals/life_below_water
name=SDG 14 - Life Below Water
description The genomic architecture underlying ecological divergence and ecological speciation with gene flow is still largely unknown for most organisms. One central question is whether divergence is genome-wide or localized in 'genomic mosaics' during early stages when gene flow is still pronounced. Empirical work has so far been limited, and the relative impacts of gene flow and natural selection on genomic patterns have not been fully explored. Here, we use ecotypes of Atlantic cod to investigate genomic patterns of diversity and population differentiation in a natural system characterized by high gene flow and large effective population sizes, properties which theoretically could restrict divergence in local genomic regions. We identify a genomic region of strong population differentiation, extending over approximately 20 cM, between pairs of migratory and stationary ecotypes examined at two different localities. Furthermore, the region is characterized by markedly reduced levels of genetic diversity in migratory ecotype samples. The results highlight the genomic region, or 'genomic island', as potentially associated with ecological divergence and suggest the involvement of a selective sweep. Finally, we also confirm earlier findings of localized genomic differentiation in three other linkage groups associated with divergence among eastern Atlantic populations. Thus, although the underlying mechanisms are still unknown, the results suggest that 'genomic mosaics' of differentiation may even be found under high levels of gene flow and that marine fishes may provide insightful model systems for studying and identifying initial targets of selection during ecological divergence.
format Article in Journal/Newspaper
author Hemmer-Hansen, Jakob
Nielsen, Einar E
Therkildsen, Nina O
Taylor, Martin I
Ogden, Rob
Geffen, Audrey J
Bekkevold, Dorte
Helyar, Sarah
Pampoulie, Christophe
Johansen, Torild
Carvalho, Gary R
author_facet Hemmer-Hansen, Jakob
Nielsen, Einar E
Therkildsen, Nina O
Taylor, Martin I
Ogden, Rob
Geffen, Audrey J
Bekkevold, Dorte
Helyar, Sarah
Pampoulie, Christophe
Johansen, Torild
Carvalho, Gary R
author_sort Hemmer-Hansen, Jakob
title A genomic island linked to ecotype divergence in Atlantic cod
title_short A genomic island linked to ecotype divergence in Atlantic cod
title_full A genomic island linked to ecotype divergence in Atlantic cod
title_fullStr A genomic island linked to ecotype divergence in Atlantic cod
title_full_unstemmed A genomic island linked to ecotype divergence in Atlantic cod
title_sort genomic island linked to ecotype divergence in atlantic cod
publishDate 2013
url https://pure.qub.ac.uk/en/publications/ec886fbd-3d29-4932-8939-2ec397b65bc1
https://doi.org/10.1111/mec.12284
https://pureadmin.qub.ac.uk/ws/files/17743931/jakob_MOL_ECOL.pdf
genre atlantic cod
Gadus morhua
genre_facet atlantic cod
Gadus morhua
op_source Hemmer-Hansen , J , Nielsen , E E , Therkildsen , N O , Taylor , M I , Ogden , R , Geffen , A J , Bekkevold , D , Helyar , S , Pampoulie , C , Johansen , T , FishPopTrace Consortium & Carvalho , G R 2013 , ' A genomic island linked to ecotype divergence in Atlantic cod ' , Molecular Ecology , vol. 22 , no. 10 , pp. 2653-67 . https://doi.org/10.1111/mec.12284
op_relation https://pure.qub.ac.uk/en/publications/ec886fbd-3d29-4932-8939-2ec397b65bc1
op_rights info:eu-repo/semantics/openAccess
op_doi https://doi.org/10.1111/mec.12284
container_title Molecular Ecology
container_volume 22
container_issue 10
container_start_page 2653
op_container_end_page 2667
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