The prevalence of age-related maculopathy in iceland:Reykjavik eye study
OBJECTIVE: To examine the age- and sex-specific prevalence of age-related maculopathy (ARM) and age-related macular degeneration (AMD) in citizens of Reykjavik, Iceland, who were 50 years and older. DESIGN: Random sample, cross sectional. MATERIALS AND METHODS: Response rate was 75.8%. The presence...
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ftqueensubelpubl:oai:pure.qub.ac.uk/portal:publications/99446cd4-1e26-4a7e-935b-855dafd9d3fd 2023-05-15T16:48:47+02:00 The prevalence of age-related maculopathy in iceland:Reykjavik eye study Jonasson, Fridbert Arnarsson, Arsaell Sasaki, Hiroshi Peto, Tunde Sasaki, Kazuyuki Bird, Alan C 2003-03 https://pure.qub.ac.uk/en/publications/the-prevalence-of-agerelated-maculopathy-in-iceland(99446cd4-1e26-4a7e-935b-855dafd9d3fd).html eng eng info:eu-repo/semantics/restrictedAccess Jonasson , F , Arnarsson , A , Sasaki , H , Peto , T , Sasaki , K & Bird , A C 2003 , ' The prevalence of age-related maculopathy in iceland : Reykjavik eye study ' , Archives of Ophthalmology , vol. 121 , no. 3 , pp. 379-85 . Age Distribution Aged 80 and over Cross-Sectional Studies Female Fundus Oculi Humans Iceland Macular Degeneration Male Middle Aged Photography Prevalence Sex Distribution Clinical Trial Journal Article Randomized Controlled Trial Research Support Non-U.S. Gov't article 2003 ftqueensubelpubl 2022-02-09T22:24:34Z OBJECTIVE: To examine the age- and sex-specific prevalence of age-related maculopathy (ARM) and age-related macular degeneration (AMD) in citizens of Reykjavik, Iceland, who were 50 years and older. DESIGN: Random sample, cross sectional. MATERIALS AND METHODS: Response rate was 75.8%. The presence and severity of various characteristics of drusen and pigmentary changes that are typical of ARM and AMD were determined by grading stereoscopic color fundus photographs, using the international classification and grading system for ARM and AMD. RESULTS: We were able to evaluate 1021 right-eye and 1020 left-eye macular photographs. There was no statistically significant difference between right and left eyes. In people aged 50 to 59 years, 4.8% of participants (95% confidence interval [CI], 2.6-7.0) were found to have intermediate soft drusen measuring 63 to 125 micro m in either eye; 1.2% (95% CI, 0.0-2.3) had large soft distinct drusen larger than 125 micro m; and 0.6% (95% CI, 0.0-1.4) had large soft, crystalline, or semisolid drusen. The same figures for those 80 years and older were 18.2% (95% CI, 9.8-26.6), 10.9% (95% CI, 4.0-17.8), and 25.5% (95% CI, 18.4-32.6), respectively. Geographic atrophy was found in either eye in 9.2% of those participants 70 years and older (95% CI, 5.6-12.7), and exudative macular degeneration was found in 2.3% of participants 70 years and older (95% CI, 0.5-4.1). CONCLUSION: Geographic atrophy was found to be more common in our study than in other population-based studies. Article in Journal/Newspaper Iceland Queen's University Belfast Research Portal |
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Open Polar |
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Queen's University Belfast Research Portal |
op_collection_id |
ftqueensubelpubl |
language |
English |
topic |
Age Distribution Aged 80 and over Cross-Sectional Studies Female Fundus Oculi Humans Iceland Macular Degeneration Male Middle Aged Photography Prevalence Sex Distribution Clinical Trial Journal Article Randomized Controlled Trial Research Support Non-U.S. Gov't |
spellingShingle |
Age Distribution Aged 80 and over Cross-Sectional Studies Female Fundus Oculi Humans Iceland Macular Degeneration Male Middle Aged Photography Prevalence Sex Distribution Clinical Trial Journal Article Randomized Controlled Trial Research Support Non-U.S. Gov't Jonasson, Fridbert Arnarsson, Arsaell Sasaki, Hiroshi Peto, Tunde Sasaki, Kazuyuki Bird, Alan C The prevalence of age-related maculopathy in iceland:Reykjavik eye study |
topic_facet |
Age Distribution Aged 80 and over Cross-Sectional Studies Female Fundus Oculi Humans Iceland Macular Degeneration Male Middle Aged Photography Prevalence Sex Distribution Clinical Trial Journal Article Randomized Controlled Trial Research Support Non-U.S. Gov't |
description |
OBJECTIVE: To examine the age- and sex-specific prevalence of age-related maculopathy (ARM) and age-related macular degeneration (AMD) in citizens of Reykjavik, Iceland, who were 50 years and older. DESIGN: Random sample, cross sectional. MATERIALS AND METHODS: Response rate was 75.8%. The presence and severity of various characteristics of drusen and pigmentary changes that are typical of ARM and AMD were determined by grading stereoscopic color fundus photographs, using the international classification and grading system for ARM and AMD. RESULTS: We were able to evaluate 1021 right-eye and 1020 left-eye macular photographs. There was no statistically significant difference between right and left eyes. In people aged 50 to 59 years, 4.8% of participants (95% confidence interval [CI], 2.6-7.0) were found to have intermediate soft drusen measuring 63 to 125 micro m in either eye; 1.2% (95% CI, 0.0-2.3) had large soft distinct drusen larger than 125 micro m; and 0.6% (95% CI, 0.0-1.4) had large soft, crystalline, or semisolid drusen. The same figures for those 80 years and older were 18.2% (95% CI, 9.8-26.6), 10.9% (95% CI, 4.0-17.8), and 25.5% (95% CI, 18.4-32.6), respectively. Geographic atrophy was found in either eye in 9.2% of those participants 70 years and older (95% CI, 5.6-12.7), and exudative macular degeneration was found in 2.3% of participants 70 years and older (95% CI, 0.5-4.1). CONCLUSION: Geographic atrophy was found to be more common in our study than in other population-based studies. |
format |
Article in Journal/Newspaper |
author |
Jonasson, Fridbert Arnarsson, Arsaell Sasaki, Hiroshi Peto, Tunde Sasaki, Kazuyuki Bird, Alan C |
author_facet |
Jonasson, Fridbert Arnarsson, Arsaell Sasaki, Hiroshi Peto, Tunde Sasaki, Kazuyuki Bird, Alan C |
author_sort |
Jonasson, Fridbert |
title |
The prevalence of age-related maculopathy in iceland:Reykjavik eye study |
title_short |
The prevalence of age-related maculopathy in iceland:Reykjavik eye study |
title_full |
The prevalence of age-related maculopathy in iceland:Reykjavik eye study |
title_fullStr |
The prevalence of age-related maculopathy in iceland:Reykjavik eye study |
title_full_unstemmed |
The prevalence of age-related maculopathy in iceland:Reykjavik eye study |
title_sort |
prevalence of age-related maculopathy in iceland:reykjavik eye study |
publishDate |
2003 |
url |
https://pure.qub.ac.uk/en/publications/the-prevalence-of-agerelated-maculopathy-in-iceland(99446cd4-1e26-4a7e-935b-855dafd9d3fd).html |
genre |
Iceland |
genre_facet |
Iceland |
op_source |
Jonasson , F , Arnarsson , A , Sasaki , H , Peto , T , Sasaki , K & Bird , A C 2003 , ' The prevalence of age-related maculopathy in iceland : Reykjavik eye study ' , Archives of Ophthalmology , vol. 121 , no. 3 , pp. 379-85 . |
op_rights |
info:eu-repo/semantics/restrictedAccess |
_version_ |
1766038870008266752 |