Prevalence of age-related maculopathy and age-related macular degeneration among the inuit in Greenland. The Greenland Inuit Eye Study
PURPOSE: To examine the age- and gender-specific prevalence and describe the common phenotype of early age-related maculopathy (ARM) and late-stage age-related macular degeneration (AMD) among the Inuit in Greenland. DESIGN: Population-based cross-sectional study. PARTICIPANTS: All > or =60-year-...
Published in: | Ophthalmology |
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Main Authors: | , , , , , , , , , |
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2008
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Online Access: | https://pure.qub.ac.uk/en/publications/prevalence-of-agerelated-maculopathy-and-agerelated-macular-degeneration-among-the-inuit-in-greenland-the-greenland-inuit-eye-study(8296505e-abcb-4a54-8447-e11596d106a0).html https://doi.org/10.1016/j.ophtha.2007.12.013 |
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ftqueensubelpubl:oai:pure.qub.ac.uk/portal:publications/8296505e-abcb-4a54-8447-e11596d106a0 2023-05-15T16:25:08+02:00 Prevalence of age-related maculopathy and age-related macular degeneration among the inuit in Greenland. The Greenland Inuit Eye Study Andersen, Mads Varis Nis Rosenberg, Thomas la Cour, Morten Kiilgaard, Jens F Prause, Jan U Alsbirk, Poul Helge Borch-Johnsen, Knut Peto, Tunde Carstensen, Bendix Bird, Alan C 2008-04 https://pure.qub.ac.uk/en/publications/prevalence-of-agerelated-maculopathy-and-agerelated-macular-degeneration-among-the-inuit-in-greenland-the-greenland-inuit-eye-study(8296505e-abcb-4a54-8447-e11596d106a0).html https://doi.org/10.1016/j.ophtha.2007.12.013 eng eng info:eu-repo/semantics/restrictedAccess Andersen , M V N , Rosenberg , T , la Cour , M , Kiilgaard , J F , Prause , J U , Alsbirk , P H , Borch-Johnsen , K , Peto , T , Carstensen , B & Bird , A C 2008 , ' Prevalence of age-related maculopathy and age-related macular degeneration among the inuit in Greenland. The Greenland Inuit Eye Study ' , Ophthalmology , vol. 115 , no. 4 , pp. 700-707.e1 . https://doi.org/10.1016/j.ophtha.2007.12.013 Age Distribution Aged 80 and over Atrophy Cross-Sectional Studies Exudates and Transudates Eye Female Fundus Oculi Greenland Humans Inuits Macular Degeneration Male Middle Aged Phenotype Prevalence Journal Article Research Support Non-U.S. Gov't article 2008 ftqueensubelpubl https://doi.org/10.1016/j.ophtha.2007.12.013 2022-02-09T22:24:34Z PURPOSE: To examine the age- and gender-specific prevalence and describe the common phenotype of early age-related maculopathy (ARM) and late-stage age-related macular degeneration (AMD) among the Inuit in Greenland. DESIGN: Population-based cross-sectional study. PARTICIPANTS: All > or =60-year-olds born in Greenland and living in the communities of Nuuk and Sisimiut, Greenland. METHODS: The presence and form of early (ARM) and late age-related macular disease (AMD) were determined by grading color fundus photographs using the international classification and grading system for ARM and AMD. MAIN OUTCOME MEASURES: Prevalences of ARM and AMD were assessed by masked grading of fundus photographs. RESULTS: Overall, 695 persons were included in the study (response rate, 74.8%). Prevalence of any ARM was 52.3%. Age-related maculopathy was present in the worse eye in 50.0%, 58.8%, and 44.7% of age groups 60 to 69, 70 to 79, and > or =80, respectively. Prevalence of any AMD was 9.5%. Any AMD was present in the worse eye in 3.9%, 14.6%, and 43.2% of age groups 60 to 69, 70 to 79, and > or =80. Prevalences of pure geographic atrophy (GA) in one or both eyes, exudative degeneration in one or both eyes, and GA in one eye and exudative degeneration in the other eye were 2.3%, 6.1%, and 1.1%, respectively. CONCLUSIONS: The prevalence of ARM is higher than in most other populations studied, and the prevalence of AMD in the oldest age group is higher than in most other populations studied. The prevalence of exudative degeneration is higher than the prevalence of GA, in contrast to findings in some of the Nordic countries-particularly Iceland-and earlier observations in Greenland. Article in Journal/Newspaper Greenland Iceland inuit inuits Nuuk Sisimiut Queen's University Belfast Research Portal Greenland Nuuk ENVELOPE(-52.150,-52.150,68.717,68.717) Sisimiut ENVELOPE(-53.674,-53.674,66.939,66.939) Ophthalmology 115 4 700 707.e1 |
institution |
Open Polar |
collection |
Queen's University Belfast Research Portal |
op_collection_id |
ftqueensubelpubl |
language |
English |
topic |
Age Distribution Aged 80 and over Atrophy Cross-Sectional Studies Exudates and Transudates Eye Female Fundus Oculi Greenland Humans Inuits Macular Degeneration Male Middle Aged Phenotype Prevalence Journal Article Research Support Non-U.S. Gov't |
spellingShingle |
Age Distribution Aged 80 and over Atrophy Cross-Sectional Studies Exudates and Transudates Eye Female Fundus Oculi Greenland Humans Inuits Macular Degeneration Male Middle Aged Phenotype Prevalence Journal Article Research Support Non-U.S. Gov't Andersen, Mads Varis Nis Rosenberg, Thomas la Cour, Morten Kiilgaard, Jens F Prause, Jan U Alsbirk, Poul Helge Borch-Johnsen, Knut Peto, Tunde Carstensen, Bendix Bird, Alan C Prevalence of age-related maculopathy and age-related macular degeneration among the inuit in Greenland. The Greenland Inuit Eye Study |
topic_facet |
Age Distribution Aged 80 and over Atrophy Cross-Sectional Studies Exudates and Transudates Eye Female Fundus Oculi Greenland Humans Inuits Macular Degeneration Male Middle Aged Phenotype Prevalence Journal Article Research Support Non-U.S. Gov't |
description |
PURPOSE: To examine the age- and gender-specific prevalence and describe the common phenotype of early age-related maculopathy (ARM) and late-stage age-related macular degeneration (AMD) among the Inuit in Greenland. DESIGN: Population-based cross-sectional study. PARTICIPANTS: All > or =60-year-olds born in Greenland and living in the communities of Nuuk and Sisimiut, Greenland. METHODS: The presence and form of early (ARM) and late age-related macular disease (AMD) were determined by grading color fundus photographs using the international classification and grading system for ARM and AMD. MAIN OUTCOME MEASURES: Prevalences of ARM and AMD were assessed by masked grading of fundus photographs. RESULTS: Overall, 695 persons were included in the study (response rate, 74.8%). Prevalence of any ARM was 52.3%. Age-related maculopathy was present in the worse eye in 50.0%, 58.8%, and 44.7% of age groups 60 to 69, 70 to 79, and > or =80, respectively. Prevalence of any AMD was 9.5%. Any AMD was present in the worse eye in 3.9%, 14.6%, and 43.2% of age groups 60 to 69, 70 to 79, and > or =80. Prevalences of pure geographic atrophy (GA) in one or both eyes, exudative degeneration in one or both eyes, and GA in one eye and exudative degeneration in the other eye were 2.3%, 6.1%, and 1.1%, respectively. CONCLUSIONS: The prevalence of ARM is higher than in most other populations studied, and the prevalence of AMD in the oldest age group is higher than in most other populations studied. The prevalence of exudative degeneration is higher than the prevalence of GA, in contrast to findings in some of the Nordic countries-particularly Iceland-and earlier observations in Greenland. |
format |
Article in Journal/Newspaper |
author |
Andersen, Mads Varis Nis Rosenberg, Thomas la Cour, Morten Kiilgaard, Jens F Prause, Jan U Alsbirk, Poul Helge Borch-Johnsen, Knut Peto, Tunde Carstensen, Bendix Bird, Alan C |
author_facet |
Andersen, Mads Varis Nis Rosenberg, Thomas la Cour, Morten Kiilgaard, Jens F Prause, Jan U Alsbirk, Poul Helge Borch-Johnsen, Knut Peto, Tunde Carstensen, Bendix Bird, Alan C |
author_sort |
Andersen, Mads Varis Nis |
title |
Prevalence of age-related maculopathy and age-related macular degeneration among the inuit in Greenland. The Greenland Inuit Eye Study |
title_short |
Prevalence of age-related maculopathy and age-related macular degeneration among the inuit in Greenland. The Greenland Inuit Eye Study |
title_full |
Prevalence of age-related maculopathy and age-related macular degeneration among the inuit in Greenland. The Greenland Inuit Eye Study |
title_fullStr |
Prevalence of age-related maculopathy and age-related macular degeneration among the inuit in Greenland. The Greenland Inuit Eye Study |
title_full_unstemmed |
Prevalence of age-related maculopathy and age-related macular degeneration among the inuit in Greenland. The Greenland Inuit Eye Study |
title_sort |
prevalence of age-related maculopathy and age-related macular degeneration among the inuit in greenland. the greenland inuit eye study |
publishDate |
2008 |
url |
https://pure.qub.ac.uk/en/publications/prevalence-of-agerelated-maculopathy-and-agerelated-macular-degeneration-among-the-inuit-in-greenland-the-greenland-inuit-eye-study(8296505e-abcb-4a54-8447-e11596d106a0).html https://doi.org/10.1016/j.ophtha.2007.12.013 |
long_lat |
ENVELOPE(-52.150,-52.150,68.717,68.717) ENVELOPE(-53.674,-53.674,66.939,66.939) |
geographic |
Greenland Nuuk Sisimiut |
geographic_facet |
Greenland Nuuk Sisimiut |
genre |
Greenland Iceland inuit inuits Nuuk Sisimiut |
genre_facet |
Greenland Iceland inuit inuits Nuuk Sisimiut |
op_source |
Andersen , M V N , Rosenberg , T , la Cour , M , Kiilgaard , J F , Prause , J U , Alsbirk , P H , Borch-Johnsen , K , Peto , T , Carstensen , B & Bird , A C 2008 , ' Prevalence of age-related maculopathy and age-related macular degeneration among the inuit in Greenland. The Greenland Inuit Eye Study ' , Ophthalmology , vol. 115 , no. 4 , pp. 700-707.e1 . https://doi.org/10.1016/j.ophtha.2007.12.013 |
op_rights |
info:eu-repo/semantics/restrictedAccess |
op_doi |
https://doi.org/10.1016/j.ophtha.2007.12.013 |
container_title |
Ophthalmology |
container_volume |
115 |
container_issue |
4 |
container_start_page |
700 |
op_container_end_page |
707.e1 |
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1766013832958836736 |