A 7-Week Summer Camp in Antarctica Induces Fluctuations on Human Oral Microbiome, Pro-Inflammatory Markers and Metabolic Hormones Profile
Antarctic camps pose psychophysiological challenges related to isolated, confined, and extreme (ICE) conditions, including meals composed of sealed food. ICE conditions can influence the microbiome and inflammatory responses. Seven expeditioners took part in a 7-week Antarctic summer camp (Nelson Is...
Published in: | Microorganisms |
---|---|
Main Authors: | , , , , , , , , , , , , , |
Format: | Text |
Language: | English |
Published: |
MDPI
2023
|
Subjects: | |
Online Access: | http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9960157/ http://www.ncbi.nlm.nih.gov/pubmed/36838304 https://doi.org/10.3390/microorganisms11020339 |
id |
ftpubmed:oai:pubmedcentral.nih.gov:9960157 |
---|---|
record_format |
openpolar |
spelling |
ftpubmed:oai:pubmedcentral.nih.gov:9960157 2023-05-15T13:40:39+02:00 A 7-Week Summer Camp in Antarctica Induces Fluctuations on Human Oral Microbiome, Pro-Inflammatory Markers and Metabolic Hormones Profile Moraes, Michele M. Mendes, Thiago T. Borges, Leandro Marques, Alice L. Núñez-Espinosa, Cristian Gonçalves, Dawit A. P. Simões, Carolina B. Vieira, Tales S. Ladeira, Roberto V. P. Lourenço, Talita G. B. Ribeiro, Danielle V. Hatanaka, Elaine Heller, Debora Arantes, Rosa M. E. 2023-01-30 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9960157/ http://www.ncbi.nlm.nih.gov/pubmed/36838304 https://doi.org/10.3390/microorganisms11020339 en eng MDPI http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9960157/ http://www.ncbi.nlm.nih.gov/pubmed/36838304 http://dx.doi.org/10.3390/microorganisms11020339 © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). CC-BY Microorganisms Article Text 2023 ftpubmed https://doi.org/10.3390/microorganisms11020339 2023-03-05T01:58:28Z Antarctic camps pose psychophysiological challenges related to isolated, confined, and extreme (ICE) conditions, including meals composed of sealed food. ICE conditions can influence the microbiome and inflammatory responses. Seven expeditioners took part in a 7-week Antarctic summer camp (Nelson Island) and were evaluated at Pre-Camp (i.e., at the beginning of the ship travel), Camp-Initial (i.e., 4th and 5th day in camp), Camp-Middle (i.e., 19th–20th, and 33rd–34th days), Camp-Final (i.e., 45th–46th day), and at the Post-Camp (on the ship). At the Pre-Camp, Camp-Initial, and Camp-Final, we assessed microbiome and inflammatory markers. Catecholamines were accessed Pre- and Post-Camp. Heart rate variability (HRV), leptin, thyroid stimulating hormone (TSH), and thyroxine (T4) were accessed at all time points. Students’ t-tests or repeated-measures analysis of variance (one or two-way ANOVA) followed by Student-Newman-Keuls (post hoc) were used for parametric analysis. Kruskal-Wallis test was applied for non-parametric analysis. Microbiome analysis showed a predominance of Pseudomonadota (34.01%), Bacillota (29.82%), and Bacteroidota (18.54%), followed by Actinomycetota (5.85%), and Fusobacteria (5.74%). Staying in a long-term Antarctic camp resulted in microbiome fluctuations with a reduction in Pseudomonadota—a “microbial signature” of disease. However, the pro-inflammatory marker leptin and IL-8 tended to increase, and the angiogenic factor VEGF was reduced during camp. These results suggest that distinct Antarctic natural environments and behavioral factors modulate oral microbiome and inflammation. Text Antarc* Antarctic Antarctica Nelson Island PubMed Central (PMC) Antarctic Nelson Island ENVELOPE(-59.050,-59.050,-62.300,-62.300) Microorganisms 11 2 339 |
institution |
Open Polar |
collection |
PubMed Central (PMC) |
op_collection_id |
ftpubmed |
language |
English |
topic |
Article |
spellingShingle |
Article Moraes, Michele M. Mendes, Thiago T. Borges, Leandro Marques, Alice L. Núñez-Espinosa, Cristian Gonçalves, Dawit A. P. Simões, Carolina B. Vieira, Tales S. Ladeira, Roberto V. P. Lourenço, Talita G. B. Ribeiro, Danielle V. Hatanaka, Elaine Heller, Debora Arantes, Rosa M. E. A 7-Week Summer Camp in Antarctica Induces Fluctuations on Human Oral Microbiome, Pro-Inflammatory Markers and Metabolic Hormones Profile |
topic_facet |
Article |
description |
Antarctic camps pose psychophysiological challenges related to isolated, confined, and extreme (ICE) conditions, including meals composed of sealed food. ICE conditions can influence the microbiome and inflammatory responses. Seven expeditioners took part in a 7-week Antarctic summer camp (Nelson Island) and were evaluated at Pre-Camp (i.e., at the beginning of the ship travel), Camp-Initial (i.e., 4th and 5th day in camp), Camp-Middle (i.e., 19th–20th, and 33rd–34th days), Camp-Final (i.e., 45th–46th day), and at the Post-Camp (on the ship). At the Pre-Camp, Camp-Initial, and Camp-Final, we assessed microbiome and inflammatory markers. Catecholamines were accessed Pre- and Post-Camp. Heart rate variability (HRV), leptin, thyroid stimulating hormone (TSH), and thyroxine (T4) were accessed at all time points. Students’ t-tests or repeated-measures analysis of variance (one or two-way ANOVA) followed by Student-Newman-Keuls (post hoc) were used for parametric analysis. Kruskal-Wallis test was applied for non-parametric analysis. Microbiome analysis showed a predominance of Pseudomonadota (34.01%), Bacillota (29.82%), and Bacteroidota (18.54%), followed by Actinomycetota (5.85%), and Fusobacteria (5.74%). Staying in a long-term Antarctic camp resulted in microbiome fluctuations with a reduction in Pseudomonadota—a “microbial signature” of disease. However, the pro-inflammatory marker leptin and IL-8 tended to increase, and the angiogenic factor VEGF was reduced during camp. These results suggest that distinct Antarctic natural environments and behavioral factors modulate oral microbiome and inflammation. |
format |
Text |
author |
Moraes, Michele M. Mendes, Thiago T. Borges, Leandro Marques, Alice L. Núñez-Espinosa, Cristian Gonçalves, Dawit A. P. Simões, Carolina B. Vieira, Tales S. Ladeira, Roberto V. P. Lourenço, Talita G. B. Ribeiro, Danielle V. Hatanaka, Elaine Heller, Debora Arantes, Rosa M. E. |
author_facet |
Moraes, Michele M. Mendes, Thiago T. Borges, Leandro Marques, Alice L. Núñez-Espinosa, Cristian Gonçalves, Dawit A. P. Simões, Carolina B. Vieira, Tales S. Ladeira, Roberto V. P. Lourenço, Talita G. B. Ribeiro, Danielle V. Hatanaka, Elaine Heller, Debora Arantes, Rosa M. E. |
author_sort |
Moraes, Michele M. |
title |
A 7-Week Summer Camp in Antarctica Induces Fluctuations on Human Oral Microbiome, Pro-Inflammatory Markers and Metabolic Hormones Profile |
title_short |
A 7-Week Summer Camp in Antarctica Induces Fluctuations on Human Oral Microbiome, Pro-Inflammatory Markers and Metabolic Hormones Profile |
title_full |
A 7-Week Summer Camp in Antarctica Induces Fluctuations on Human Oral Microbiome, Pro-Inflammatory Markers and Metabolic Hormones Profile |
title_fullStr |
A 7-Week Summer Camp in Antarctica Induces Fluctuations on Human Oral Microbiome, Pro-Inflammatory Markers and Metabolic Hormones Profile |
title_full_unstemmed |
A 7-Week Summer Camp in Antarctica Induces Fluctuations on Human Oral Microbiome, Pro-Inflammatory Markers and Metabolic Hormones Profile |
title_sort |
7-week summer camp in antarctica induces fluctuations on human oral microbiome, pro-inflammatory markers and metabolic hormones profile |
publisher |
MDPI |
publishDate |
2023 |
url |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9960157/ http://www.ncbi.nlm.nih.gov/pubmed/36838304 https://doi.org/10.3390/microorganisms11020339 |
long_lat |
ENVELOPE(-59.050,-59.050,-62.300,-62.300) |
geographic |
Antarctic Nelson Island |
geographic_facet |
Antarctic Nelson Island |
genre |
Antarc* Antarctic Antarctica Nelson Island |
genre_facet |
Antarc* Antarctic Antarctica Nelson Island |
op_source |
Microorganisms |
op_relation |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9960157/ http://www.ncbi.nlm.nih.gov/pubmed/36838304 http://dx.doi.org/10.3390/microorganisms11020339 |
op_rights |
© 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
op_rightsnorm |
CC-BY |
op_doi |
https://doi.org/10.3390/microorganisms11020339 |
container_title |
Microorganisms |
container_volume |
11 |
container_issue |
2 |
container_start_page |
339 |
_version_ |
1766137994633281536 |