Sores of boreal moose reveal a previously unknown genetic lineage of parasitic nematode within the genus Onchocerca
Long-standing reports of open sores on the hind legs of moose (Alces alces) have been recorded in Alaska (as well as Canada, Europe, and Michigan), eliciting concerns about causes and infection. We used histological and genomic methods to investigate the sores from 20 adult moose on the Kenai Penins...
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ftpubmed:oai:pubmedcentral.nih.gov:9833588 2023-05-15T13:13:17+02:00 Sores of boreal moose reveal a previously unknown genetic lineage of parasitic nematode within the genus Onchocerca Benedict, Bridgett M. Barboza, Perry S. Crouse, John A. Groch, Katia R. Kulpa, Matthew R. Thompson, Dan P. Verocai, Guilherme G. Wiener, Dominique J. 2023-01-11 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9833588/ http://www.ncbi.nlm.nih.gov/pubmed/36630399 https://doi.org/10.1371/journal.pone.0278886 en eng Public Library of Science http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9833588/ http://www.ncbi.nlm.nih.gov/pubmed/36630399 http://dx.doi.org/10.1371/journal.pone.0278886 © 2023 Benedict et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. CC-BY PLoS One Research Article Text 2023 ftpubmed https://doi.org/10.1371/journal.pone.0278886 2023-01-15T02:05:43Z Long-standing reports of open sores on the hind legs of moose (Alces alces) have been recorded in Alaska (as well as Canada, Europe, and Michigan), eliciting concerns about causes and infection. We used histological and genomic methods to investigate the sores from 20 adult moose on the Kenai Peninsula, Alaska. We paired this with thermal imagery and molt scoring of adult moose to further describe sore formation and understand its timing. Severe, ulcerative and eosinophilic dermatitis was found in all moose with sores present, and microfilariae within intraepidermal pustules were additionally found in four samples. Genetic analysis of sores from moose revealed a previously unknown genetic lineage of Onchocerca. Adult moose molt and lose their barrier of protection against flies in June and July during peak fly activity, leaving them vulnerable and allowing the development of sores. In summary, our results indicate that the cause for the sores on the hindleg of moose is a previously unknown genetic lineage of Onchocerca, probably transmitted by black flies, in timing with the molt cycle of adult moose. These sores leave moose exposed to pathogens, making them vulnerable, and challenging their health and fitness. Text Alces alces Alaska PubMed Central (PMC) Canada PLOS ONE 18 1 e0278886 |
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Research Article Benedict, Bridgett M. Barboza, Perry S. Crouse, John A. Groch, Katia R. Kulpa, Matthew R. Thompson, Dan P. Verocai, Guilherme G. Wiener, Dominique J. Sores of boreal moose reveal a previously unknown genetic lineage of parasitic nematode within the genus Onchocerca |
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Research Article |
description |
Long-standing reports of open sores on the hind legs of moose (Alces alces) have been recorded in Alaska (as well as Canada, Europe, and Michigan), eliciting concerns about causes and infection. We used histological and genomic methods to investigate the sores from 20 adult moose on the Kenai Peninsula, Alaska. We paired this with thermal imagery and molt scoring of adult moose to further describe sore formation and understand its timing. Severe, ulcerative and eosinophilic dermatitis was found in all moose with sores present, and microfilariae within intraepidermal pustules were additionally found in four samples. Genetic analysis of sores from moose revealed a previously unknown genetic lineage of Onchocerca. Adult moose molt and lose their barrier of protection against flies in June and July during peak fly activity, leaving them vulnerable and allowing the development of sores. In summary, our results indicate that the cause for the sores on the hindleg of moose is a previously unknown genetic lineage of Onchocerca, probably transmitted by black flies, in timing with the molt cycle of adult moose. These sores leave moose exposed to pathogens, making them vulnerable, and challenging their health and fitness. |
format |
Text |
author |
Benedict, Bridgett M. Barboza, Perry S. Crouse, John A. Groch, Katia R. Kulpa, Matthew R. Thompson, Dan P. Verocai, Guilherme G. Wiener, Dominique J. |
author_facet |
Benedict, Bridgett M. Barboza, Perry S. Crouse, John A. Groch, Katia R. Kulpa, Matthew R. Thompson, Dan P. Verocai, Guilherme G. Wiener, Dominique J. |
author_sort |
Benedict, Bridgett M. |
title |
Sores of boreal moose reveal a previously unknown genetic lineage of parasitic nematode within the genus Onchocerca |
title_short |
Sores of boreal moose reveal a previously unknown genetic lineage of parasitic nematode within the genus Onchocerca |
title_full |
Sores of boreal moose reveal a previously unknown genetic lineage of parasitic nematode within the genus Onchocerca |
title_fullStr |
Sores of boreal moose reveal a previously unknown genetic lineage of parasitic nematode within the genus Onchocerca |
title_full_unstemmed |
Sores of boreal moose reveal a previously unknown genetic lineage of parasitic nematode within the genus Onchocerca |
title_sort |
sores of boreal moose reveal a previously unknown genetic lineage of parasitic nematode within the genus onchocerca |
publisher |
Public Library of Science |
publishDate |
2023 |
url |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9833588/ http://www.ncbi.nlm.nih.gov/pubmed/36630399 https://doi.org/10.1371/journal.pone.0278886 |
geographic |
Canada |
geographic_facet |
Canada |
genre |
Alces alces Alaska |
genre_facet |
Alces alces Alaska |
op_source |
PLoS One |
op_relation |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9833588/ http://www.ncbi.nlm.nih.gov/pubmed/36630399 http://dx.doi.org/10.1371/journal.pone.0278886 |
op_rights |
© 2023 Benedict et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
op_rightsnorm |
CC-BY |
op_doi |
https://doi.org/10.1371/journal.pone.0278886 |
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PLOS ONE |
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18 |
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1 |
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e0278886 |
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