Novel adenovirus associated with necrotizing bronchiolitis in a captive reindeer (Rangifer tarandus)
Adenoviruses cause a range of major diseases across many diverse animal species including ruminants. They are classified into six genera in the family Adenoviridae. In deer species, two adenoviruses are currently recognized: deer adenovirus 1 in the Atadenovirus genus, and deer adenovirus 2 in the M...
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ftpubmed:oai:pubmedcentral.nih.gov:9787489 2023-05-15T18:04:14+02:00 Novel adenovirus associated with necrotizing bronchiolitis in a captive reindeer (Rangifer tarandus) Dastjerdi, Akbar Jeckel, Sonja Davies, Hannah Irving, Jennifer Longue, Camille Plummer, Charlotte Vidovszky, Márton Z. Harrach, Balázs Chantrey, Julian Martineau, Henny Williams, Jonathan 2021-11-22 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9787489/ http://www.ncbi.nlm.nih.gov/pubmed/34724349 https://doi.org/10.1111/tbed.14374 en eng John Wiley and Sons Inc. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9787489/ http://www.ncbi.nlm.nih.gov/pubmed/34724349 http://dx.doi.org/10.1111/tbed.14374 © 2021 Crown copyright. Transboundary and Emerging Diseases published by Wiley‐VCH GmbH. This article is published with the permission of the Controller of HMSO and the Queen's Printer for Scotland. https://creativecommons.org/licenses/by-nc/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes. CC-BY-NC Transbound Emerg Dis Short Communications Text 2021 ftpubmed https://doi.org/10.1111/tbed.14374 2023-01-01T01:34:09Z Adenoviruses cause a range of major diseases across many diverse animal species including ruminants. They are classified into six genera in the family Adenoviridae. In deer species, two adenoviruses are currently recognized: deer adenovirus 1 in the Atadenovirus genus, and deer adenovirus 2 in the Mastadenovirus genus. Deer adenovirus 1 causes adenovirus haemorrhagic disease with high fatality in black‐tailed and mule deer in North America. Conversely, deer adenovirus 2 was incidentally detected from a healthy white‐tailed deer fawn, but experimentally it has been shown to cause pyrexia, cough and moderate to severe haemorrhage. Here, we detected a novel adenovirus, reindeer adenovirus 1, from lung lesions of a 5‐year‐old male reindeer (Rangifer tarandus). This animal presented with aspiration pneumonia and necrotizing bronchiolitis following a period of clinical weakness, nasal discharge and wasting. Histopathological examination of the lung revealed large intranuclear basophilic inclusions associated with the areas of necrotizing bronchiolitis. Next generation sequencing of the lung tissue identified a novel mastadenovirus with close similarity to deer adenovirus 2 and bovine adenovirus 3. To our knowledge, this is the first report of a deer mastadenovirus associated with necrotizing bronchiolitis in captive reindeer. Text Rangifer tarandus PubMed Central (PMC) Transboundary and Emerging Diseases 69 5 3097 3102 |
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Short Communications |
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Short Communications Dastjerdi, Akbar Jeckel, Sonja Davies, Hannah Irving, Jennifer Longue, Camille Plummer, Charlotte Vidovszky, Márton Z. Harrach, Balázs Chantrey, Julian Martineau, Henny Williams, Jonathan Novel adenovirus associated with necrotizing bronchiolitis in a captive reindeer (Rangifer tarandus) |
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Short Communications |
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Adenoviruses cause a range of major diseases across many diverse animal species including ruminants. They are classified into six genera in the family Adenoviridae. In deer species, two adenoviruses are currently recognized: deer adenovirus 1 in the Atadenovirus genus, and deer adenovirus 2 in the Mastadenovirus genus. Deer adenovirus 1 causes adenovirus haemorrhagic disease with high fatality in black‐tailed and mule deer in North America. Conversely, deer adenovirus 2 was incidentally detected from a healthy white‐tailed deer fawn, but experimentally it has been shown to cause pyrexia, cough and moderate to severe haemorrhage. Here, we detected a novel adenovirus, reindeer adenovirus 1, from lung lesions of a 5‐year‐old male reindeer (Rangifer tarandus). This animal presented with aspiration pneumonia and necrotizing bronchiolitis following a period of clinical weakness, nasal discharge and wasting. Histopathological examination of the lung revealed large intranuclear basophilic inclusions associated with the areas of necrotizing bronchiolitis. Next generation sequencing of the lung tissue identified a novel mastadenovirus with close similarity to deer adenovirus 2 and bovine adenovirus 3. To our knowledge, this is the first report of a deer mastadenovirus associated with necrotizing bronchiolitis in captive reindeer. |
format |
Text |
author |
Dastjerdi, Akbar Jeckel, Sonja Davies, Hannah Irving, Jennifer Longue, Camille Plummer, Charlotte Vidovszky, Márton Z. Harrach, Balázs Chantrey, Julian Martineau, Henny Williams, Jonathan |
author_facet |
Dastjerdi, Akbar Jeckel, Sonja Davies, Hannah Irving, Jennifer Longue, Camille Plummer, Charlotte Vidovszky, Márton Z. Harrach, Balázs Chantrey, Julian Martineau, Henny Williams, Jonathan |
author_sort |
Dastjerdi, Akbar |
title |
Novel adenovirus associated with necrotizing bronchiolitis in a captive reindeer (Rangifer tarandus) |
title_short |
Novel adenovirus associated with necrotizing bronchiolitis in a captive reindeer (Rangifer tarandus) |
title_full |
Novel adenovirus associated with necrotizing bronchiolitis in a captive reindeer (Rangifer tarandus) |
title_fullStr |
Novel adenovirus associated with necrotizing bronchiolitis in a captive reindeer (Rangifer tarandus) |
title_full_unstemmed |
Novel adenovirus associated with necrotizing bronchiolitis in a captive reindeer (Rangifer tarandus) |
title_sort |
novel adenovirus associated with necrotizing bronchiolitis in a captive reindeer (rangifer tarandus) |
publisher |
John Wiley and Sons Inc. |
publishDate |
2021 |
url |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9787489/ http://www.ncbi.nlm.nih.gov/pubmed/34724349 https://doi.org/10.1111/tbed.14374 |
genre |
Rangifer tarandus |
genre_facet |
Rangifer tarandus |
op_source |
Transbound Emerg Dis |
op_relation |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9787489/ http://www.ncbi.nlm.nih.gov/pubmed/34724349 http://dx.doi.org/10.1111/tbed.14374 |
op_rights |
© 2021 Crown copyright. Transboundary and Emerging Diseases published by Wiley‐VCH GmbH. This article is published with the permission of the Controller of HMSO and the Queen's Printer for Scotland. https://creativecommons.org/licenses/by-nc/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes. |
op_rightsnorm |
CC-BY-NC |
op_doi |
https://doi.org/10.1111/tbed.14374 |
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Transboundary and Emerging Diseases |
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69 |
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5 |
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3097 |
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3102 |
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