Metallothionein Expression as a Physiological Response against Metal Toxicity in the Striped Rockcod Trematomus hansoni
Metal bioaccumulation and metallothionein (MT) expression were investigated in the gills and liver of the red-blooded Antarctic teleost Trematomus hansoni to evaluate the possibility for this species to face, with adequate physiological responses, an increase of copper and cadmium concentrations in...
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Online Access: | http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9657541/ http://www.ncbi.nlm.nih.gov/pubmed/36361591 https://doi.org/10.3390/ijms232112799 |
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ftpubmed:oai:pubmedcentral.nih.gov:9657541 2023-05-15T14:04:15+02:00 Metallothionein Expression as a Physiological Response against Metal Toxicity in the Striped Rockcod Trematomus hansoni Bakiu, Rigers Pacchini, Sara Piva, Elisabetta Schumann, Sophia Tolomeo, Anna Maria Ferro, Diana Irato, Paola Santovito, Gianfranco 2022-10-24 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9657541/ http://www.ncbi.nlm.nih.gov/pubmed/36361591 https://doi.org/10.3390/ijms232112799 en eng MDPI http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9657541/ http://www.ncbi.nlm.nih.gov/pubmed/36361591 http://dx.doi.org/10.3390/ijms232112799 © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). CC-BY Int J Mol Sci Article Text 2022 ftpubmed https://doi.org/10.3390/ijms232112799 2022-11-20T02:37:37Z Metal bioaccumulation and metallothionein (MT) expression were investigated in the gills and liver of the red-blooded Antarctic teleost Trematomus hansoni to evaluate the possibility for this species to face, with adequate physiological responses, an increase of copper and cadmium concentrations in its tissues. Specimens of this Antarctic fish were collected from Terra Nova Bay (Ross Sea) and used for a metal exposure experiment in controlled laboratory conditions. The two treatments led to a significant accumulation of both metals and increased gene transcription only for the MT-1. The biosynthesis of MTs was verified especially in specimens exposed to Cd, but most of these proteins were soon oxidized, probably because they were involved in cell protection against oxidative stress risk by scavenging reactive oxygen species. The obtained data highlighted the phenotypic plasticity of T. hansoni, a species that evolved in an environment characterized by naturally high concentrations of Cu and Cd, and maybe the possibility for the Antarctic fish to face the challenges of a world that is becoming more toxic every day. Text Antarc* Antarctic Ross Sea PubMed Central (PMC) Antarctic Ross Sea Terra Nova Bay The Antarctic International Journal of Molecular Sciences 23 21 12799 |
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Article Bakiu, Rigers Pacchini, Sara Piva, Elisabetta Schumann, Sophia Tolomeo, Anna Maria Ferro, Diana Irato, Paola Santovito, Gianfranco Metallothionein Expression as a Physiological Response against Metal Toxicity in the Striped Rockcod Trematomus hansoni |
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Metal bioaccumulation and metallothionein (MT) expression were investigated in the gills and liver of the red-blooded Antarctic teleost Trematomus hansoni to evaluate the possibility for this species to face, with adequate physiological responses, an increase of copper and cadmium concentrations in its tissues. Specimens of this Antarctic fish were collected from Terra Nova Bay (Ross Sea) and used for a metal exposure experiment in controlled laboratory conditions. The two treatments led to a significant accumulation of both metals and increased gene transcription only for the MT-1. The biosynthesis of MTs was verified especially in specimens exposed to Cd, but most of these proteins were soon oxidized, probably because they were involved in cell protection against oxidative stress risk by scavenging reactive oxygen species. The obtained data highlighted the phenotypic plasticity of T. hansoni, a species that evolved in an environment characterized by naturally high concentrations of Cu and Cd, and maybe the possibility for the Antarctic fish to face the challenges of a world that is becoming more toxic every day. |
format |
Text |
author |
Bakiu, Rigers Pacchini, Sara Piva, Elisabetta Schumann, Sophia Tolomeo, Anna Maria Ferro, Diana Irato, Paola Santovito, Gianfranco |
author_facet |
Bakiu, Rigers Pacchini, Sara Piva, Elisabetta Schumann, Sophia Tolomeo, Anna Maria Ferro, Diana Irato, Paola Santovito, Gianfranco |
author_sort |
Bakiu, Rigers |
title |
Metallothionein Expression as a Physiological Response against Metal Toxicity in the Striped Rockcod Trematomus hansoni |
title_short |
Metallothionein Expression as a Physiological Response against Metal Toxicity in the Striped Rockcod Trematomus hansoni |
title_full |
Metallothionein Expression as a Physiological Response against Metal Toxicity in the Striped Rockcod Trematomus hansoni |
title_fullStr |
Metallothionein Expression as a Physiological Response against Metal Toxicity in the Striped Rockcod Trematomus hansoni |
title_full_unstemmed |
Metallothionein Expression as a Physiological Response against Metal Toxicity in the Striped Rockcod Trematomus hansoni |
title_sort |
metallothionein expression as a physiological response against metal toxicity in the striped rockcod trematomus hansoni |
publisher |
MDPI |
publishDate |
2022 |
url |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9657541/ http://www.ncbi.nlm.nih.gov/pubmed/36361591 https://doi.org/10.3390/ijms232112799 |
geographic |
Antarctic Ross Sea Terra Nova Bay The Antarctic |
geographic_facet |
Antarctic Ross Sea Terra Nova Bay The Antarctic |
genre |
Antarc* Antarctic Ross Sea |
genre_facet |
Antarc* Antarctic Ross Sea |
op_source |
Int J Mol Sci |
op_relation |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9657541/ http://www.ncbi.nlm.nih.gov/pubmed/36361591 http://dx.doi.org/10.3390/ijms232112799 |
op_rights |
© 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
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CC-BY |
op_doi |
https://doi.org/10.3390/ijms232112799 |
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International Journal of Molecular Sciences |
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23 |
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21 |
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12799 |
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1766275272659697664 |