Clinical Remission of Asthma and Allergic Rhinitis - in a Longitudinal Population Study
BACKGROUND: Although asthma and allergic rhinitis are chronic diseases, some patients experience periods of remission. Information on prognostic factors associated with the remission of asthma and allergic rhinitis is valuable in resource prioritization. This study investigated factors associated wi...
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ftpubmed:oai:pubmedcentral.nih.gov:9643071 2023-05-15T16:52:19+02:00 Clinical Remission of Asthma and Allergic Rhinitis - in a Longitudinal Population Study Heldin, Johanna Malinovschi, Andrei Johannessen, Ane Alving, Kjell Holm, Mathias Franklin, Karl A Forsberg, Bertil Schlünssen, Vivi Jögi, Rain Gislason, Thorarinn Benediktsdottir, Bryndis Svanes, Cecilie Janson, Christer 2022-11-04 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9643071/ https://doi.org/10.2147/JAA.S378584 en eng Dove http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9643071/ http://dx.doi.org/10.2147/JAA.S378584 © 2022 Heldin et al. https://creativecommons.org/licenses/by-nc/3.0/This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/ (https://creativecommons.org/licenses/by-nc/3.0/) ). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php). CC-BY-NC J Asthma Allergy Original Research Text 2022 ftpubmed https://doi.org/10.2147/JAA.S378584 2022-11-20T02:00:59Z BACKGROUND: Although asthma and allergic rhinitis are chronic diseases, some patients experience periods of remission. Information on prognostic factors associated with the remission of asthma and allergic rhinitis is valuable in resource prioritization. This study investigated factors associated with the clinical remission of asthma and allergic rhinitis. METHODS: In the Respiratory Health In Northern Europe (RHINE) study, data was collected with questionnaires in stage one (RHINE I, 1989–1992) and two follow-ups (RHINE II, 1999–2001 and RHINE III, 2010–2012) from Sweden, Norway, Denmark, Iceland and Estonia. Clinical remission was defined as having reported asthma or allergic rhinitis in RHINE I or RHINE II but not in RHINE III. RESULTS: Of 13,052 participants, 975 (7.5%) reported asthma in RHINE I or RHINE II, and 3379 (25.9%) allergic rhinitis. Clinical remission of asthma and allergic rhinitis was found in 46.4% and 31.8%, respectively. Living in Estonia (OR (95% CI) 2.44 (1.22–4.85)) and living in an apartment (1.45 (1.06–1.98)) were related to remission of asthma, while subjects reporting allergic rhinitis (0.68 (0.51–0.90)), asthma onset ≤ 12 years of age (0.49 (0.35–0.68)), receiving treatment with antibiotics for respiratory illness (0.64 (0.47–0.87)) were less likely to have asthma remission. Factors related to a higher likelihood of remission of allergic rhinitis were no asthma at baseline, age ≥ 58 years in RHINE III, allergic rhinitis onset after 12 years of age, living in rural areas as a child, having only a primary school education and not being pregnant. CONCLUSION: Clinical remission was found in almost one-half of those with asthma and one-third of persons with allergic rhinitis. Coexisting allergic symptoms were associated with less clinical asthma remission. Age, asthma symptoms and environmental factors in childhood, such as living in a rural area, were found to influence the clinical remission of allergic rhinitis. Text Iceland PubMed Central (PMC) Norway Journal of Asthma and Allergy Volume 15 1569 1578 |
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Original Research Heldin, Johanna Malinovschi, Andrei Johannessen, Ane Alving, Kjell Holm, Mathias Franklin, Karl A Forsberg, Bertil Schlünssen, Vivi Jögi, Rain Gislason, Thorarinn Benediktsdottir, Bryndis Svanes, Cecilie Janson, Christer Clinical Remission of Asthma and Allergic Rhinitis - in a Longitudinal Population Study |
topic_facet |
Original Research |
description |
BACKGROUND: Although asthma and allergic rhinitis are chronic diseases, some patients experience periods of remission. Information on prognostic factors associated with the remission of asthma and allergic rhinitis is valuable in resource prioritization. This study investigated factors associated with the clinical remission of asthma and allergic rhinitis. METHODS: In the Respiratory Health In Northern Europe (RHINE) study, data was collected with questionnaires in stage one (RHINE I, 1989–1992) and two follow-ups (RHINE II, 1999–2001 and RHINE III, 2010–2012) from Sweden, Norway, Denmark, Iceland and Estonia. Clinical remission was defined as having reported asthma or allergic rhinitis in RHINE I or RHINE II but not in RHINE III. RESULTS: Of 13,052 participants, 975 (7.5%) reported asthma in RHINE I or RHINE II, and 3379 (25.9%) allergic rhinitis. Clinical remission of asthma and allergic rhinitis was found in 46.4% and 31.8%, respectively. Living in Estonia (OR (95% CI) 2.44 (1.22–4.85)) and living in an apartment (1.45 (1.06–1.98)) were related to remission of asthma, while subjects reporting allergic rhinitis (0.68 (0.51–0.90)), asthma onset ≤ 12 years of age (0.49 (0.35–0.68)), receiving treatment with antibiotics for respiratory illness (0.64 (0.47–0.87)) were less likely to have asthma remission. Factors related to a higher likelihood of remission of allergic rhinitis were no asthma at baseline, age ≥ 58 years in RHINE III, allergic rhinitis onset after 12 years of age, living in rural areas as a child, having only a primary school education and not being pregnant. CONCLUSION: Clinical remission was found in almost one-half of those with asthma and one-third of persons with allergic rhinitis. Coexisting allergic symptoms were associated with less clinical asthma remission. Age, asthma symptoms and environmental factors in childhood, such as living in a rural area, were found to influence the clinical remission of allergic rhinitis. |
format |
Text |
author |
Heldin, Johanna Malinovschi, Andrei Johannessen, Ane Alving, Kjell Holm, Mathias Franklin, Karl A Forsberg, Bertil Schlünssen, Vivi Jögi, Rain Gislason, Thorarinn Benediktsdottir, Bryndis Svanes, Cecilie Janson, Christer |
author_facet |
Heldin, Johanna Malinovschi, Andrei Johannessen, Ane Alving, Kjell Holm, Mathias Franklin, Karl A Forsberg, Bertil Schlünssen, Vivi Jögi, Rain Gislason, Thorarinn Benediktsdottir, Bryndis Svanes, Cecilie Janson, Christer |
author_sort |
Heldin, Johanna |
title |
Clinical Remission of Asthma and Allergic Rhinitis - in a Longitudinal Population Study |
title_short |
Clinical Remission of Asthma and Allergic Rhinitis - in a Longitudinal Population Study |
title_full |
Clinical Remission of Asthma and Allergic Rhinitis - in a Longitudinal Population Study |
title_fullStr |
Clinical Remission of Asthma and Allergic Rhinitis - in a Longitudinal Population Study |
title_full_unstemmed |
Clinical Remission of Asthma and Allergic Rhinitis - in a Longitudinal Population Study |
title_sort |
clinical remission of asthma and allergic rhinitis - in a longitudinal population study |
publisher |
Dove |
publishDate |
2022 |
url |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9643071/ https://doi.org/10.2147/JAA.S378584 |
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Norway |
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Norway |
genre |
Iceland |
genre_facet |
Iceland |
op_source |
J Asthma Allergy |
op_relation |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9643071/ http://dx.doi.org/10.2147/JAA.S378584 |
op_rights |
© 2022 Heldin et al. https://creativecommons.org/licenses/by-nc/3.0/This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/ (https://creativecommons.org/licenses/by-nc/3.0/) ). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php). |
op_rightsnorm |
CC-BY-NC |
op_doi |
https://doi.org/10.2147/JAA.S378584 |
container_title |
Journal of Asthma and Allergy |
container_volume |
Volume 15 |
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1569 |
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1578 |
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1766042456918327296 |