A comparative and ontogenetic examination of mitochondrial function in Antarctic notothenioid species
Notothenioidei fishes have evolved under stable cold temperatures; however, ocean conditions are changing globally, with polar regions poised to experience the greatest changes in environmental factors, such as warming. These stressors have the potential to dramatically affect energetic demands, and...
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ftpubmed:oai:pubmedcentral.nih.gov:9550766 2023-05-15T13:49:48+02:00 A comparative and ontogenetic examination of mitochondrial function in Antarctic notothenioid species Mandic, Milica Frazier, Amanda J. Naslund, Andrew W. Todgham, Anne E. 2022-09-14 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9550766/ http://www.ncbi.nlm.nih.gov/pubmed/36104549 https://doi.org/10.1007/s00360-022-01461-6 en eng Springer Berlin Heidelberg http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9550766/ http://www.ncbi.nlm.nih.gov/pubmed/36104549 http://dx.doi.org/10.1007/s00360-022-01461-6 © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . CC-BY J Comp Physiol B Original Paper Text 2022 ftpubmed https://doi.org/10.1007/s00360-022-01461-6 2022-10-16T00:48:01Z Notothenioidei fishes have evolved under stable cold temperatures; however, ocean conditions are changing globally, with polar regions poised to experience the greatest changes in environmental factors, such as warming. These stressors have the potential to dramatically affect energetic demands, and the persistence of the notothenioids will be dependent on metabolic capacity, or the ability to match energy supply with energy demand, to restore homeostasis in the face of changing climate conditions. In this study we examined aerobic metabolic capacity in three species, Trematomus bernacchii, T. pennellii and T. newnesi, and between two life stages, juvenile and adult, by assessing mitochondrial function of permeabilized cardiac fibers. Respiratory capacity differed among the adult notothenioids in this study, with greater oxidative phosphorylation (OXPHOS) respiration in the pelagic T. newnesi than the benthic T. bernacchii and T. pennellii. The variation in mitochondrial respiratory capacity was likely driven by differences in the mitochondrial content, as measured by citrate synthase activity, which was the highest in T. newnesi. In addition to high OXPHOS, T. newnesi exhibited lower LEAK respiration, resulting in greater mitochondrial efficiency than either T. bernacchii or T. pennellii. Life stage largely had an effect on mitochondrial efficiency and excess complex IV capacity, but there were little differences in OXPHOS respiration and electron transfer capacity, pointing to a lack of significant differences in the metabolic capacity between juveniles and adults. Overall, these results demonstrate species-specific differences in cardiac metabolic capacity, which may influence the acclimation potential of notothenioid fishes to changing environmental conditions. Text Antarc* Antarctic PubMed Central (PMC) Antarctic Journal of Comparative Physiology B 192 6 737 750 |
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Original Paper |
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Original Paper Mandic, Milica Frazier, Amanda J. Naslund, Andrew W. Todgham, Anne E. A comparative and ontogenetic examination of mitochondrial function in Antarctic notothenioid species |
topic_facet |
Original Paper |
description |
Notothenioidei fishes have evolved under stable cold temperatures; however, ocean conditions are changing globally, with polar regions poised to experience the greatest changes in environmental factors, such as warming. These stressors have the potential to dramatically affect energetic demands, and the persistence of the notothenioids will be dependent on metabolic capacity, or the ability to match energy supply with energy demand, to restore homeostasis in the face of changing climate conditions. In this study we examined aerobic metabolic capacity in three species, Trematomus bernacchii, T. pennellii and T. newnesi, and between two life stages, juvenile and adult, by assessing mitochondrial function of permeabilized cardiac fibers. Respiratory capacity differed among the adult notothenioids in this study, with greater oxidative phosphorylation (OXPHOS) respiration in the pelagic T. newnesi than the benthic T. bernacchii and T. pennellii. The variation in mitochondrial respiratory capacity was likely driven by differences in the mitochondrial content, as measured by citrate synthase activity, which was the highest in T. newnesi. In addition to high OXPHOS, T. newnesi exhibited lower LEAK respiration, resulting in greater mitochondrial efficiency than either T. bernacchii or T. pennellii. Life stage largely had an effect on mitochondrial efficiency and excess complex IV capacity, but there were little differences in OXPHOS respiration and electron transfer capacity, pointing to a lack of significant differences in the metabolic capacity between juveniles and adults. Overall, these results demonstrate species-specific differences in cardiac metabolic capacity, which may influence the acclimation potential of notothenioid fishes to changing environmental conditions. |
format |
Text |
author |
Mandic, Milica Frazier, Amanda J. Naslund, Andrew W. Todgham, Anne E. |
author_facet |
Mandic, Milica Frazier, Amanda J. Naslund, Andrew W. Todgham, Anne E. |
author_sort |
Mandic, Milica |
title |
A comparative and ontogenetic examination of mitochondrial function in Antarctic notothenioid species |
title_short |
A comparative and ontogenetic examination of mitochondrial function in Antarctic notothenioid species |
title_full |
A comparative and ontogenetic examination of mitochondrial function in Antarctic notothenioid species |
title_fullStr |
A comparative and ontogenetic examination of mitochondrial function in Antarctic notothenioid species |
title_full_unstemmed |
A comparative and ontogenetic examination of mitochondrial function in Antarctic notothenioid species |
title_sort |
comparative and ontogenetic examination of mitochondrial function in antarctic notothenioid species |
publisher |
Springer Berlin Heidelberg |
publishDate |
2022 |
url |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9550766/ http://www.ncbi.nlm.nih.gov/pubmed/36104549 https://doi.org/10.1007/s00360-022-01461-6 |
geographic |
Antarctic |
geographic_facet |
Antarctic |
genre |
Antarc* Antarctic |
genre_facet |
Antarc* Antarctic |
op_source |
J Comp Physiol B |
op_relation |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9550766/ http://www.ncbi.nlm.nih.gov/pubmed/36104549 http://dx.doi.org/10.1007/s00360-022-01461-6 |
op_rights |
© The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
op_rightsnorm |
CC-BY |
op_doi |
https://doi.org/10.1007/s00360-022-01461-6 |
container_title |
Journal of Comparative Physiology B |
container_volume |
192 |
container_issue |
6 |
container_start_page |
737 |
op_container_end_page |
750 |
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1766252305588420608 |