Real World Studies of Psoriasis and Mental Illness in Newfoundland and Labrador
BACKGROUND: Psoriasis is a chronic, immune-mediated inflammatory disease with an implied connection to psychiatric disorders. OBJECTIVE: This study aims to illustrate an association between psoriasis and psychiatric disorders using real world data gathered from the Newfoundland and Labrador populati...
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Online Access: | http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9476230/ http://www.ncbi.nlm.nih.gov/pubmed/35938546 https://doi.org/10.1177/12034754221117736 |
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ftpubmed:oai:pubmedcentral.nih.gov:9476230 2023-05-15T17:21:13+02:00 Real World Studies of Psoriasis and Mental Illness in Newfoundland and Labrador Badaiki, Winifred Penney, Michelle Pyper, Evelyn Lester, Kendra Skeard, Janelle Shin, Janey Fisher, Brenda Gulliver, Susanne Gulliver, Wayne Rahman, Proton 2022-08-07 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9476230/ http://www.ncbi.nlm.nih.gov/pubmed/35938546 https://doi.org/10.1177/12034754221117736 en eng SAGE Publications http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9476230/ http://www.ncbi.nlm.nih.gov/pubmed/35938546 http://dx.doi.org/10.1177/12034754221117736 © The Author(s) 2022 https://creativecommons.org/licenses/by-nc/4.0/This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage). CC-BY-NC J Cutan Med Surg Original Articles Text 2022 ftpubmed https://doi.org/10.1177/12034754221117736 2022-09-18T00:57:10Z BACKGROUND: Psoriasis is a chronic, immune-mediated inflammatory disease with an implied connection to psychiatric disorders. OBJECTIVE: This study aims to illustrate an association between psoriasis and psychiatric disorders using real world data gathered from the Newfoundland and Labrador population. METHODS: Data on 15,100 patients with psoriasis and 75,500 controls (1:5) was collected from the Newfoundland and Labrador Centre for Health Information’s Electronic Health Records. The cases and controls were matched for age, sex, and geography. Indicators for psychiatric disorders include diagnosis of mental illnesses from physician’s visits and hospitalization records (all coded for mental health using ICD-9 and ICD-10 codes). RESULTS: 9,991 (66.2%) cases were identified to have at least one visit with a diagnostic code for mental illness compared to 42,276 (56.0%), P < .0001 in the control group. The percentage of people coded for anxiety was 36.50% compared to 28.95%, P < .0001; depression was 37.04% compared to 30.19%, P < .0001; and adjustment disorder was 6.89% versus 5.48%, P < .0001, among those with and without psoriasis, respectively. The greatest risk for anxiety [OR 1.4 (1.20, 1.67)] and depression [OR 1.65 (1.36, 2.00)] among psoriasis patients was between the 0 to 20 age group. Women with psoriasis are more likely to have anxiety [OR 1.08 (1.03, 1.13)], depression [OR 1.04 (1.01, 1.09)] and adjustment disorder [OR 1.07 (0.98, 1.17)] compared to female controls. CONCLUSION: Our result shows that patients with psoriasis have an increased prevalence of mental illness. Using real world data to carry out further investigations will better elucidate this association and provide an increased understanding of the association between psoriasis and mental disorders. Text Newfoundland PubMed Central (PMC) Newfoundland Journal of Cutaneous Medicine and Surgery 26 5 494 501 |
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Original Articles Badaiki, Winifred Penney, Michelle Pyper, Evelyn Lester, Kendra Skeard, Janelle Shin, Janey Fisher, Brenda Gulliver, Susanne Gulliver, Wayne Rahman, Proton Real World Studies of Psoriasis and Mental Illness in Newfoundland and Labrador |
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Original Articles |
description |
BACKGROUND: Psoriasis is a chronic, immune-mediated inflammatory disease with an implied connection to psychiatric disorders. OBJECTIVE: This study aims to illustrate an association between psoriasis and psychiatric disorders using real world data gathered from the Newfoundland and Labrador population. METHODS: Data on 15,100 patients with psoriasis and 75,500 controls (1:5) was collected from the Newfoundland and Labrador Centre for Health Information’s Electronic Health Records. The cases and controls were matched for age, sex, and geography. Indicators for psychiatric disorders include diagnosis of mental illnesses from physician’s visits and hospitalization records (all coded for mental health using ICD-9 and ICD-10 codes). RESULTS: 9,991 (66.2%) cases were identified to have at least one visit with a diagnostic code for mental illness compared to 42,276 (56.0%), P < .0001 in the control group. The percentage of people coded for anxiety was 36.50% compared to 28.95%, P < .0001; depression was 37.04% compared to 30.19%, P < .0001; and adjustment disorder was 6.89% versus 5.48%, P < .0001, among those with and without psoriasis, respectively. The greatest risk for anxiety [OR 1.4 (1.20, 1.67)] and depression [OR 1.65 (1.36, 2.00)] among psoriasis patients was between the 0 to 20 age group. Women with psoriasis are more likely to have anxiety [OR 1.08 (1.03, 1.13)], depression [OR 1.04 (1.01, 1.09)] and adjustment disorder [OR 1.07 (0.98, 1.17)] compared to female controls. CONCLUSION: Our result shows that patients with psoriasis have an increased prevalence of mental illness. Using real world data to carry out further investigations will better elucidate this association and provide an increased understanding of the association between psoriasis and mental disorders. |
format |
Text |
author |
Badaiki, Winifred Penney, Michelle Pyper, Evelyn Lester, Kendra Skeard, Janelle Shin, Janey Fisher, Brenda Gulliver, Susanne Gulliver, Wayne Rahman, Proton |
author_facet |
Badaiki, Winifred Penney, Michelle Pyper, Evelyn Lester, Kendra Skeard, Janelle Shin, Janey Fisher, Brenda Gulliver, Susanne Gulliver, Wayne Rahman, Proton |
author_sort |
Badaiki, Winifred |
title |
Real World Studies of Psoriasis and Mental Illness in Newfoundland and Labrador |
title_short |
Real World Studies of Psoriasis and Mental Illness in Newfoundland and Labrador |
title_full |
Real World Studies of Psoriasis and Mental Illness in Newfoundland and Labrador |
title_fullStr |
Real World Studies of Psoriasis and Mental Illness in Newfoundland and Labrador |
title_full_unstemmed |
Real World Studies of Psoriasis and Mental Illness in Newfoundland and Labrador |
title_sort |
real world studies of psoriasis and mental illness in newfoundland and labrador |
publisher |
SAGE Publications |
publishDate |
2022 |
url |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9476230/ http://www.ncbi.nlm.nih.gov/pubmed/35938546 https://doi.org/10.1177/12034754221117736 |
geographic |
Newfoundland |
geographic_facet |
Newfoundland |
genre |
Newfoundland |
genre_facet |
Newfoundland |
op_source |
J Cutan Med Surg |
op_relation |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9476230/ http://www.ncbi.nlm.nih.gov/pubmed/35938546 http://dx.doi.org/10.1177/12034754221117736 |
op_rights |
© The Author(s) 2022 https://creativecommons.org/licenses/by-nc/4.0/This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage). |
op_rightsnorm |
CC-BY-NC |
op_doi |
https://doi.org/10.1177/12034754221117736 |
container_title |
Journal of Cutaneous Medicine and Surgery |
container_volume |
26 |
container_issue |
5 |
container_start_page |
494 |
op_container_end_page |
501 |
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1766104723857866752 |