Artemisia spp.: An Update on Its Chemical Composition, Pharmacological and Toxicological Profiles
Artemisia plants are traditional and ethnopharmacologically used to treat several diseases and in addition in food, spices, and beverages. The genus is widely distributed in all continents except the Antarctica, and traditional medicine has been used as antimalarial, antioxidant, anticancer, antinoc...
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ftpubmed:oai:pubmedcentral.nih.gov:9467740 2023-05-15T13:41:54+02:00 Artemisia spp.: An Update on Its Chemical Composition, Pharmacological and Toxicological Profiles Sharifi-Rad, Javad Herrera-Bravo, Jesús Semwal, Prabhakar Painuli, Sakshi Badoni, Himani Ezzat, Shahira M. Farid, Mai M. Merghany, Rana M. Aborehab, Nora M. Salem, Mohamed A. Sen, Surjit Acharya, Krishnendu Lapava, Natallia Martorell, Miquel Tynybekov, Bekzat Calina, Daniela Cho, William C. 2022-09-05 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9467740/ http://www.ncbi.nlm.nih.gov/pubmed/36105486 https://doi.org/10.1155/2022/5628601 en eng Hindawi http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9467740/ http://www.ncbi.nlm.nih.gov/pubmed/36105486 http://dx.doi.org/10.1155/2022/5628601 Copyright © 2022 Javad Sharifi-Rad et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. CC-BY Oxid Med Cell Longev Review Article Text 2022 ftpubmed https://doi.org/10.1155/2022/5628601 2022-09-18T00:44:55Z Artemisia plants are traditional and ethnopharmacologically used to treat several diseases and in addition in food, spices, and beverages. The genus is widely distributed in all continents except the Antarctica, and traditional medicine has been used as antimalarial, antioxidant, anticancer, antinociceptive, anti-inflammatory, and antiviral agents. This review is aimed at systematizing scientific data on the geographical distribution, chemical composition, and pharmacological and toxicological profiles of the Artemisia genus. Data from the literature on Artemisia plants were taken using electronic databases such as PubMed/MEDLINE, Scopus, and Web of Science. Selected papers for this updated study included data about phytochemicals, preclinical pharmacological experimental studies with molecular mechanisms included, clinical studies, and toxicological and safety data. In addition, ancient texts and books were consulted. The essential oils and phytochemicals of the Artemisia genus have reported important biological activities, among them the artemisinin, a sesquiterpene lactone, with antimalarial activity. Artemisia absinthium L. is one of the most famous Artemisia spp. due to its use in the production of the absinthe drink which is restricted in most countries because of neurotoxicity. The analyzed studies confirmed that Artemisia plants have many traditional and pharmacological applications. However, scientific data are limited to clinical and toxicological research. Therefore, further research is needed on these aspects to understand the full therapeutic potential and molecular pharmacological mechanisms of this medicinal species. Text Antarc* Antarctica PubMed Central (PMC) Oxidative Medicine and Cellular Longevity 2022 1 23 |
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Review Article |
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Review Article Sharifi-Rad, Javad Herrera-Bravo, Jesús Semwal, Prabhakar Painuli, Sakshi Badoni, Himani Ezzat, Shahira M. Farid, Mai M. Merghany, Rana M. Aborehab, Nora M. Salem, Mohamed A. Sen, Surjit Acharya, Krishnendu Lapava, Natallia Martorell, Miquel Tynybekov, Bekzat Calina, Daniela Cho, William C. Artemisia spp.: An Update on Its Chemical Composition, Pharmacological and Toxicological Profiles |
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Review Article |
description |
Artemisia plants are traditional and ethnopharmacologically used to treat several diseases and in addition in food, spices, and beverages. The genus is widely distributed in all continents except the Antarctica, and traditional medicine has been used as antimalarial, antioxidant, anticancer, antinociceptive, anti-inflammatory, and antiviral agents. This review is aimed at systematizing scientific data on the geographical distribution, chemical composition, and pharmacological and toxicological profiles of the Artemisia genus. Data from the literature on Artemisia plants were taken using electronic databases such as PubMed/MEDLINE, Scopus, and Web of Science. Selected papers for this updated study included data about phytochemicals, preclinical pharmacological experimental studies with molecular mechanisms included, clinical studies, and toxicological and safety data. In addition, ancient texts and books were consulted. The essential oils and phytochemicals of the Artemisia genus have reported important biological activities, among them the artemisinin, a sesquiterpene lactone, with antimalarial activity. Artemisia absinthium L. is one of the most famous Artemisia spp. due to its use in the production of the absinthe drink which is restricted in most countries because of neurotoxicity. The analyzed studies confirmed that Artemisia plants have many traditional and pharmacological applications. However, scientific data are limited to clinical and toxicological research. Therefore, further research is needed on these aspects to understand the full therapeutic potential and molecular pharmacological mechanisms of this medicinal species. |
format |
Text |
author |
Sharifi-Rad, Javad Herrera-Bravo, Jesús Semwal, Prabhakar Painuli, Sakshi Badoni, Himani Ezzat, Shahira M. Farid, Mai M. Merghany, Rana M. Aborehab, Nora M. Salem, Mohamed A. Sen, Surjit Acharya, Krishnendu Lapava, Natallia Martorell, Miquel Tynybekov, Bekzat Calina, Daniela Cho, William C. |
author_facet |
Sharifi-Rad, Javad Herrera-Bravo, Jesús Semwal, Prabhakar Painuli, Sakshi Badoni, Himani Ezzat, Shahira M. Farid, Mai M. Merghany, Rana M. Aborehab, Nora M. Salem, Mohamed A. Sen, Surjit Acharya, Krishnendu Lapava, Natallia Martorell, Miquel Tynybekov, Bekzat Calina, Daniela Cho, William C. |
author_sort |
Sharifi-Rad, Javad |
title |
Artemisia spp.: An Update on Its Chemical Composition, Pharmacological and Toxicological Profiles |
title_short |
Artemisia spp.: An Update on Its Chemical Composition, Pharmacological and Toxicological Profiles |
title_full |
Artemisia spp.: An Update on Its Chemical Composition, Pharmacological and Toxicological Profiles |
title_fullStr |
Artemisia spp.: An Update on Its Chemical Composition, Pharmacological and Toxicological Profiles |
title_full_unstemmed |
Artemisia spp.: An Update on Its Chemical Composition, Pharmacological and Toxicological Profiles |
title_sort |
artemisia spp.: an update on its chemical composition, pharmacological and toxicological profiles |
publisher |
Hindawi |
publishDate |
2022 |
url |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9467740/ http://www.ncbi.nlm.nih.gov/pubmed/36105486 https://doi.org/10.1155/2022/5628601 |
genre |
Antarc* Antarctica |
genre_facet |
Antarc* Antarctica |
op_source |
Oxid Med Cell Longev |
op_relation |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9467740/ http://www.ncbi.nlm.nih.gov/pubmed/36105486 http://dx.doi.org/10.1155/2022/5628601 |
op_rights |
Copyright © 2022 Javad Sharifi-Rad et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
op_rightsnorm |
CC-BY |
op_doi |
https://doi.org/10.1155/2022/5628601 |
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Oxidative Medicine and Cellular Longevity |
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2022 |
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1 |
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23 |
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