Two‐phase sample selection strategies for design and analysis in post‐genome‐wide association fine‐mapping studies

Post‐GWAS analysis, in many cases, focuses on fine‐mapping targeted genetic regions discovered at GWAS‐stage; that is, the aim is to pinpoint potential causal variants and susceptibility genes for complex traits and disease outcomes using next‐generation sequencing (NGS) technologies. Large‐scale GW...

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Bibliographic Details
Published in:Statistics in Medicine
Main Authors: Espin‐Garcia, Osvaldo, Craiu, Radu V., Bull, Shelley B.
Format: Text
Language:English
Published: John Wiley and Sons Inc. 2021
Subjects:
Online Access:http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9293221/
http://www.ncbi.nlm.nih.gov/pubmed/34596256
https://doi.org/10.1002/sim.9211