Antioxidant Response during the Kinetics of Anhydrobiosis in Two Eutardigrade Species
Anhydrobiosis, a peculiar adaptive strategy existing in nature, is a reversible capability of organisms to tolerate a severe loss of their body water when their surrounding habitat is drying out. In the anhydrobiotic state, an organism lacks all dynamic features of living beings since an ongoing met...
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ftpubmed:oai:pubmedcentral.nih.gov:9225123 2023-05-15T13:03:41+02:00 Antioxidant Response during the Kinetics of Anhydrobiosis in Two Eutardigrade Species Giovannini, Ilaria Corsetto, Paola Antonia Altiero, Tiziana Montorfano, Gigliola Guidetti, Roberto Rizzo, Angela Maria Rebecchi, Lorena 2022-05-30 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9225123/ https://doi.org/10.3390/life12060817 en eng MDPI http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9225123/ http://dx.doi.org/10.3390/life12060817 © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). CC-BY Life (Basel) Article Text 2022 ftpubmed https://doi.org/10.3390/life12060817 2022-06-26T01:07:59Z Anhydrobiosis, a peculiar adaptive strategy existing in nature, is a reversible capability of organisms to tolerate a severe loss of their body water when their surrounding habitat is drying out. In the anhydrobiotic state, an organism lacks all dynamic features of living beings since an ongoing metabolism is absent. The depletion of water in the anhydrobiotic state increases the ionic concentration and the production of reactive oxygen species (ROS). An imbalance between the increased production of ROS and the limited action of antioxidant defences is a source of biomolecular damage and can lead to oxidative stress. The deleterious effects of oxidative stress were demonstrated in anhydrobiotic unicellular and multicellular organisms, which counteract the effects using efficient antioxidant machinery, mainly represented by ROS scavenger enzymes. To gain insights into the dynamics of antioxidant patterns during the kinetics of the anhydrobiosis of two tardigrade species, Paramacrobiotus spatialis and Acutuncus antarcticus, we investigated the activity of enzymatic antioxidants (catalase, superoxide dismutase, glutathione peroxidase, and glutathione reductase) and the amount of non-enzymatic antioxidants (glutathione) in the course of rehydration. In P. spatialis, the activity of catalase increases during dehydration and decreases during rehydration, whereas in A. antarcticus, the activity of superoxide dismutase decreases during desiccation and increases during rehydration. Genomic varieties, different habitats and geographical regions, different diets, and diverse evolutionary lineages may have led to the specialization of antioxidant strategies in the two species. Text Acutuncus antarcticus Antarc* antarcticus Tardigrade PubMed Central (PMC) Life 12 6 817 |
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Article Giovannini, Ilaria Corsetto, Paola Antonia Altiero, Tiziana Montorfano, Gigliola Guidetti, Roberto Rizzo, Angela Maria Rebecchi, Lorena Antioxidant Response during the Kinetics of Anhydrobiosis in Two Eutardigrade Species |
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Anhydrobiosis, a peculiar adaptive strategy existing in nature, is a reversible capability of organisms to tolerate a severe loss of their body water when their surrounding habitat is drying out. In the anhydrobiotic state, an organism lacks all dynamic features of living beings since an ongoing metabolism is absent. The depletion of water in the anhydrobiotic state increases the ionic concentration and the production of reactive oxygen species (ROS). An imbalance between the increased production of ROS and the limited action of antioxidant defences is a source of biomolecular damage and can lead to oxidative stress. The deleterious effects of oxidative stress were demonstrated in anhydrobiotic unicellular and multicellular organisms, which counteract the effects using efficient antioxidant machinery, mainly represented by ROS scavenger enzymes. To gain insights into the dynamics of antioxidant patterns during the kinetics of the anhydrobiosis of two tardigrade species, Paramacrobiotus spatialis and Acutuncus antarcticus, we investigated the activity of enzymatic antioxidants (catalase, superoxide dismutase, glutathione peroxidase, and glutathione reductase) and the amount of non-enzymatic antioxidants (glutathione) in the course of rehydration. In P. spatialis, the activity of catalase increases during dehydration and decreases during rehydration, whereas in A. antarcticus, the activity of superoxide dismutase decreases during desiccation and increases during rehydration. Genomic varieties, different habitats and geographical regions, different diets, and diverse evolutionary lineages may have led to the specialization of antioxidant strategies in the two species. |
format |
Text |
author |
Giovannini, Ilaria Corsetto, Paola Antonia Altiero, Tiziana Montorfano, Gigliola Guidetti, Roberto Rizzo, Angela Maria Rebecchi, Lorena |
author_facet |
Giovannini, Ilaria Corsetto, Paola Antonia Altiero, Tiziana Montorfano, Gigliola Guidetti, Roberto Rizzo, Angela Maria Rebecchi, Lorena |
author_sort |
Giovannini, Ilaria |
title |
Antioxidant Response during the Kinetics of Anhydrobiosis in Two Eutardigrade Species |
title_short |
Antioxidant Response during the Kinetics of Anhydrobiosis in Two Eutardigrade Species |
title_full |
Antioxidant Response during the Kinetics of Anhydrobiosis in Two Eutardigrade Species |
title_fullStr |
Antioxidant Response during the Kinetics of Anhydrobiosis in Two Eutardigrade Species |
title_full_unstemmed |
Antioxidant Response during the Kinetics of Anhydrobiosis in Two Eutardigrade Species |
title_sort |
antioxidant response during the kinetics of anhydrobiosis in two eutardigrade species |
publisher |
MDPI |
publishDate |
2022 |
url |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9225123/ https://doi.org/10.3390/life12060817 |
genre |
Acutuncus antarcticus Antarc* antarcticus Tardigrade |
genre_facet |
Acutuncus antarcticus Antarc* antarcticus Tardigrade |
op_source |
Life (Basel) |
op_relation |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9225123/ http://dx.doi.org/10.3390/life12060817 |
op_rights |
© 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
op_rightsnorm |
CC-BY |
op_doi |
https://doi.org/10.3390/life12060817 |
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Life |
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12 |
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6 |
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817 |
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