Hematologic and plasma biochemical prognostic indicators for stranded free-ranging phocids presented for rehabilitation
This retrospective study used data obtained from medical records of 530 stranded free-ranging harbor (Phoca vitulina), grey (Halichoerus grypus), harp (Pagophilus groenlandicus), and hooded seals (Cystophora cristata) presented to the Marine Mammal Stranding Center in Brigantine, New Jersey from Jan...
Published in: | Scientific Reports |
---|---|
Main Authors: | , , , , , |
Format: | Text |
Language: | English |
Published: |
Nature Publishing Group UK
2022
|
Subjects: | |
Online Access: | http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9217849/ https://doi.org/10.1038/s41598-022-14923-2 |
id |
ftpubmed:oai:pubmedcentral.nih.gov:9217849 |
---|---|
record_format |
openpolar |
spelling |
ftpubmed:oai:pubmedcentral.nih.gov:9217849 2023-05-15T15:59:53+02:00 Hematologic and plasma biochemical prognostic indicators for stranded free-ranging phocids presented for rehabilitation Vail, Matthew Beaufrère, Hugues Gallini, Stefan Paluch, Hubert Brandão, João DiGeronimo, Peter M. 2022-06-22 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9217849/ https://doi.org/10.1038/s41598-022-14923-2 en eng Nature Publishing Group UK http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9217849/ http://dx.doi.org/10.1038/s41598-022-14923-2 © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . CC-BY Sci Rep Article Text 2022 ftpubmed https://doi.org/10.1038/s41598-022-14923-2 2022-06-26T00:50:53Z This retrospective study used data obtained from medical records of 530 stranded free-ranging harbor (Phoca vitulina), grey (Halichoerus grypus), harp (Pagophilus groenlandicus), and hooded seals (Cystophora cristata) presented to the Marine Mammal Stranding Center in Brigantine, New Jersey from January 1998 through December 2016. The objective was to identify hematological and plasma biochemical parameters of seals at time of presentation that were associated with successful rehabilitation and with duration of hospitalization using univariate and multivariate logistic regressions. At presentation, animals that subsequently survived rehabilitation had greater alkaline phosphatase activity and absolute lymphocyte and total calcium concentrations and lower blood urea nitrogen, sodium, chloride, phosphorus, and total bilirubin concentrations and lower aspartate aminotransferase and alanine aminotransferase activities than animals that eventually died or were euthanized while under care. Results suggest that young, actively growing animals are more likely to survive rehabilitation and that bloodwork consistent with dehydration, systemic disease, and exhaustion are negative prognostic indicators. These results provide prognostic indicators that may aid clinical decision-making for seals presented for rehabilitation. Text Cystophora cristata Pagophilus groenlandicus Phoca vitulina PubMed Central (PMC) Scientific Reports 12 1 |
institution |
Open Polar |
collection |
PubMed Central (PMC) |
op_collection_id |
ftpubmed |
language |
English |
topic |
Article |
spellingShingle |
Article Vail, Matthew Beaufrère, Hugues Gallini, Stefan Paluch, Hubert Brandão, João DiGeronimo, Peter M. Hematologic and plasma biochemical prognostic indicators for stranded free-ranging phocids presented for rehabilitation |
topic_facet |
Article |
description |
This retrospective study used data obtained from medical records of 530 stranded free-ranging harbor (Phoca vitulina), grey (Halichoerus grypus), harp (Pagophilus groenlandicus), and hooded seals (Cystophora cristata) presented to the Marine Mammal Stranding Center in Brigantine, New Jersey from January 1998 through December 2016. The objective was to identify hematological and plasma biochemical parameters of seals at time of presentation that were associated with successful rehabilitation and with duration of hospitalization using univariate and multivariate logistic regressions. At presentation, animals that subsequently survived rehabilitation had greater alkaline phosphatase activity and absolute lymphocyte and total calcium concentrations and lower blood urea nitrogen, sodium, chloride, phosphorus, and total bilirubin concentrations and lower aspartate aminotransferase and alanine aminotransferase activities than animals that eventually died or were euthanized while under care. Results suggest that young, actively growing animals are more likely to survive rehabilitation and that bloodwork consistent with dehydration, systemic disease, and exhaustion are negative prognostic indicators. These results provide prognostic indicators that may aid clinical decision-making for seals presented for rehabilitation. |
format |
Text |
author |
Vail, Matthew Beaufrère, Hugues Gallini, Stefan Paluch, Hubert Brandão, João DiGeronimo, Peter M. |
author_facet |
Vail, Matthew Beaufrère, Hugues Gallini, Stefan Paluch, Hubert Brandão, João DiGeronimo, Peter M. |
author_sort |
Vail, Matthew |
title |
Hematologic and plasma biochemical prognostic indicators for stranded free-ranging phocids presented for rehabilitation |
title_short |
Hematologic and plasma biochemical prognostic indicators for stranded free-ranging phocids presented for rehabilitation |
title_full |
Hematologic and plasma biochemical prognostic indicators for stranded free-ranging phocids presented for rehabilitation |
title_fullStr |
Hematologic and plasma biochemical prognostic indicators for stranded free-ranging phocids presented for rehabilitation |
title_full_unstemmed |
Hematologic and plasma biochemical prognostic indicators for stranded free-ranging phocids presented for rehabilitation |
title_sort |
hematologic and plasma biochemical prognostic indicators for stranded free-ranging phocids presented for rehabilitation |
publisher |
Nature Publishing Group UK |
publishDate |
2022 |
url |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9217849/ https://doi.org/10.1038/s41598-022-14923-2 |
genre |
Cystophora cristata Pagophilus groenlandicus Phoca vitulina |
genre_facet |
Cystophora cristata Pagophilus groenlandicus Phoca vitulina |
op_source |
Sci Rep |
op_relation |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9217849/ http://dx.doi.org/10.1038/s41598-022-14923-2 |
op_rights |
© The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
op_rightsnorm |
CC-BY |
op_doi |
https://doi.org/10.1038/s41598-022-14923-2 |
container_title |
Scientific Reports |
container_volume |
12 |
container_issue |
1 |
_version_ |
1766395780053073920 |