Of fruits and fats: high-sugar diets restore fatty acid profiles in the white adipose tissue of captive dwarf lemurs
Fat-storing hibernators rely on fatty acids from white adipose tissue (WAT) as an energy source to sustain hibernation. Whereas arctic and temperate hibernators preferentially recruit dietary polyunsaturated fatty acids (PUFAs), tropical hibernators can rely on monounsaturated fatty acids that produ...
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ftpubmed:oai:pubmedcentral.nih.gov:9198768 2023-07-23T04:17:55+02:00 Of fruits and fats: high-sugar diets restore fatty acid profiles in the white adipose tissue of captive dwarf lemurs Blanco, M. B. Greene, L. K. Ellsaesser, L. N. Schopler, B. Davison, M. Ostrowski, C. Klopfer, P. H. Fietz, J. Ehmke, E. E. 2022-06-29 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9198768/ http://www.ncbi.nlm.nih.gov/pubmed/35703045 https://doi.org/10.1098/rspb.2022.0598 en eng The Royal Society http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9198768/ http://www.ncbi.nlm.nih.gov/pubmed/35703045 http://dx.doi.org/10.1098/rspb.2022.0598 © 2022 The Author(s) https://royalsociety.org/-/media/journals/author/Licence-to-Publish-20062019-final.pdfhttps://royalsociety.org/journals/ethics-policies/data-sharing-mining/Published by the Royal Society. All rights reserved. Proc Biol Sci Development and Physiology Text 2022 ftpubmed https://doi.org/10.1098/rspb.2022.0598 2023-07-02T00:39:18Z Fat-storing hibernators rely on fatty acids from white adipose tissue (WAT) as an energy source to sustain hibernation. Whereas arctic and temperate hibernators preferentially recruit dietary polyunsaturated fatty acids (PUFAs), tropical hibernators can rely on monounsaturated fatty acids that produce fewer lipid peroxides during oxidation. Nevertheless, compositional data on WAT from tropical hibernators are scant and questions remain regarding fat recruitment and metabolism under different environmental conditions. We analyse fatty acid profiles from the WAT of captive dwarf lemurs (Cheirogaleus medius) subjected to high-sugar or high-fat diets during fattening and cold or warm conditions during hibernation. Dwarf lemurs fed high-sugar (compared to high-fat) diets displayed WAT profiles more comparable to wild lemurs that fatten on fruits and better depleted their fat reserves during hibernation. One PUFA, linoleic acid, remained elevated before hibernation, potentially lingering from the diets provisioned prior to fattening. That dwarf lemurs preferentially recruit the PUFA linoleic acid from diets that are naturally low in availability could explain the discrepancy between captive and wild lemurs' WAT. While demonstrating that minor dietary changes can produce major changes in seasonal fat deposition and depletion, our results highlight the complex role for PUFA metabolism in the ecology of tropical hibernators. Text Arctic PubMed Central (PMC) Arctic Proceedings of the Royal Society B: Biological Sciences 289 1977 |
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PubMed Central (PMC) |
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ftpubmed |
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English |
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Development and Physiology |
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Development and Physiology Blanco, M. B. Greene, L. K. Ellsaesser, L. N. Schopler, B. Davison, M. Ostrowski, C. Klopfer, P. H. Fietz, J. Ehmke, E. E. Of fruits and fats: high-sugar diets restore fatty acid profiles in the white adipose tissue of captive dwarf lemurs |
topic_facet |
Development and Physiology |
description |
Fat-storing hibernators rely on fatty acids from white adipose tissue (WAT) as an energy source to sustain hibernation. Whereas arctic and temperate hibernators preferentially recruit dietary polyunsaturated fatty acids (PUFAs), tropical hibernators can rely on monounsaturated fatty acids that produce fewer lipid peroxides during oxidation. Nevertheless, compositional data on WAT from tropical hibernators are scant and questions remain regarding fat recruitment and metabolism under different environmental conditions. We analyse fatty acid profiles from the WAT of captive dwarf lemurs (Cheirogaleus medius) subjected to high-sugar or high-fat diets during fattening and cold or warm conditions during hibernation. Dwarf lemurs fed high-sugar (compared to high-fat) diets displayed WAT profiles more comparable to wild lemurs that fatten on fruits and better depleted their fat reserves during hibernation. One PUFA, linoleic acid, remained elevated before hibernation, potentially lingering from the diets provisioned prior to fattening. That dwarf lemurs preferentially recruit the PUFA linoleic acid from diets that are naturally low in availability could explain the discrepancy between captive and wild lemurs' WAT. While demonstrating that minor dietary changes can produce major changes in seasonal fat deposition and depletion, our results highlight the complex role for PUFA metabolism in the ecology of tropical hibernators. |
format |
Text |
author |
Blanco, M. B. Greene, L. K. Ellsaesser, L. N. Schopler, B. Davison, M. Ostrowski, C. Klopfer, P. H. Fietz, J. Ehmke, E. E. |
author_facet |
Blanco, M. B. Greene, L. K. Ellsaesser, L. N. Schopler, B. Davison, M. Ostrowski, C. Klopfer, P. H. Fietz, J. Ehmke, E. E. |
author_sort |
Blanco, M. B. |
title |
Of fruits and fats: high-sugar diets restore fatty acid profiles in the white adipose tissue of captive dwarf lemurs |
title_short |
Of fruits and fats: high-sugar diets restore fatty acid profiles in the white adipose tissue of captive dwarf lemurs |
title_full |
Of fruits and fats: high-sugar diets restore fatty acid profiles in the white adipose tissue of captive dwarf lemurs |
title_fullStr |
Of fruits and fats: high-sugar diets restore fatty acid profiles in the white adipose tissue of captive dwarf lemurs |
title_full_unstemmed |
Of fruits and fats: high-sugar diets restore fatty acid profiles in the white adipose tissue of captive dwarf lemurs |
title_sort |
of fruits and fats: high-sugar diets restore fatty acid profiles in the white adipose tissue of captive dwarf lemurs |
publisher |
The Royal Society |
publishDate |
2022 |
url |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9198768/ http://www.ncbi.nlm.nih.gov/pubmed/35703045 https://doi.org/10.1098/rspb.2022.0598 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Proc Biol Sci |
op_relation |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9198768/ http://www.ncbi.nlm.nih.gov/pubmed/35703045 http://dx.doi.org/10.1098/rspb.2022.0598 |
op_rights |
© 2022 The Author(s) https://royalsociety.org/-/media/journals/author/Licence-to-Publish-20062019-final.pdfhttps://royalsociety.org/journals/ethics-policies/data-sharing-mining/Published by the Royal Society. All rights reserved. |
op_doi |
https://doi.org/10.1098/rspb.2022.0598 |
container_title |
Proceedings of the Royal Society B: Biological Sciences |
container_volume |
289 |
container_issue |
1977 |
_version_ |
1772180007263666176 |