North Asian population relationships in a global context
Population genetic studies of North Asian ethnic groups have focused on genetic variation of sex chromosomes and mitochondria. Studies of the extensive variation available from autosomal variation have appeared infrequently. We focus on relationships among population samples using new North Asia mic...
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ftpubmed:oai:pubmedcentral.nih.gov:9068624 2023-05-15T17:02:51+02:00 North Asian population relationships in a global context Kidd, Kenneth K. Evsanaa, Baigalmaa Togtokh, Ariunaa Brissenden, Jane E. Roscoe, Janet M. Dogan, Mustafa Neophytou, Pavlos I. Gurkan, Cemal Bulbul, Ozlem Cherni, Lotfi Speed, William C. Murtha, Michael Kidd, Judith R. Pakstis, Andrew J. 2022-05-04 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9068624/ https://doi.org/10.1038/s41598-022-10706-x en eng Nature Publishing Group UK http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9068624/ http://dx.doi.org/10.1038/s41598-022-10706-x © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . CC-BY Sci Rep Article Text 2022 ftpubmed https://doi.org/10.1038/s41598-022-10706-x 2022-05-08T01:20:43Z Population genetic studies of North Asian ethnic groups have focused on genetic variation of sex chromosomes and mitochondria. Studies of the extensive variation available from autosomal variation have appeared infrequently. We focus on relationships among population samples using new North Asia microhaplotype data. We combined genotypes from our laboratory on 58 microhaplotypes, distributed across 18 autosomes, on 3945 individuals from 75 populations with corresponding data extracted for 26 populations from the Thousand Genomes consortium and for 22 populations from the GenomeAsia 100 K project. A total of 7107 individuals in 122 total populations are analyzed using STRUCTURE, Principal Component Analysis, and phylogenetic tree analyses. North Asia populations sampled in Mongolia include: Buryats, Mongolians, Altai Kazakhs, and Tsaatans. Available Siberians include samples of Yakut, Khanty, and Komi Zyriane. Analyses of all 122 populations confirm many known relationships and show that most populations from North Asia form a cluster distinct from all other groups. Refinement of analyses on smaller subsets of populations reinforces the distinctiveness of North Asia and shows that the North Asia cluster identifies a region that is ancestral to Native Americans. Text khanty PubMed Central (PMC) Scientific Reports 12 1 |
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Article Kidd, Kenneth K. Evsanaa, Baigalmaa Togtokh, Ariunaa Brissenden, Jane E. Roscoe, Janet M. Dogan, Mustafa Neophytou, Pavlos I. Gurkan, Cemal Bulbul, Ozlem Cherni, Lotfi Speed, William C. Murtha, Michael Kidd, Judith R. Pakstis, Andrew J. North Asian population relationships in a global context |
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Population genetic studies of North Asian ethnic groups have focused on genetic variation of sex chromosomes and mitochondria. Studies of the extensive variation available from autosomal variation have appeared infrequently. We focus on relationships among population samples using new North Asia microhaplotype data. We combined genotypes from our laboratory on 58 microhaplotypes, distributed across 18 autosomes, on 3945 individuals from 75 populations with corresponding data extracted for 26 populations from the Thousand Genomes consortium and for 22 populations from the GenomeAsia 100 K project. A total of 7107 individuals in 122 total populations are analyzed using STRUCTURE, Principal Component Analysis, and phylogenetic tree analyses. North Asia populations sampled in Mongolia include: Buryats, Mongolians, Altai Kazakhs, and Tsaatans. Available Siberians include samples of Yakut, Khanty, and Komi Zyriane. Analyses of all 122 populations confirm many known relationships and show that most populations from North Asia form a cluster distinct from all other groups. Refinement of analyses on smaller subsets of populations reinforces the distinctiveness of North Asia and shows that the North Asia cluster identifies a region that is ancestral to Native Americans. |
format |
Text |
author |
Kidd, Kenneth K. Evsanaa, Baigalmaa Togtokh, Ariunaa Brissenden, Jane E. Roscoe, Janet M. Dogan, Mustafa Neophytou, Pavlos I. Gurkan, Cemal Bulbul, Ozlem Cherni, Lotfi Speed, William C. Murtha, Michael Kidd, Judith R. Pakstis, Andrew J. |
author_facet |
Kidd, Kenneth K. Evsanaa, Baigalmaa Togtokh, Ariunaa Brissenden, Jane E. Roscoe, Janet M. Dogan, Mustafa Neophytou, Pavlos I. Gurkan, Cemal Bulbul, Ozlem Cherni, Lotfi Speed, William C. Murtha, Michael Kidd, Judith R. Pakstis, Andrew J. |
author_sort |
Kidd, Kenneth K. |
title |
North Asian population relationships in a global context |
title_short |
North Asian population relationships in a global context |
title_full |
North Asian population relationships in a global context |
title_fullStr |
North Asian population relationships in a global context |
title_full_unstemmed |
North Asian population relationships in a global context |
title_sort |
north asian population relationships in a global context |
publisher |
Nature Publishing Group UK |
publishDate |
2022 |
url |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9068624/ https://doi.org/10.1038/s41598-022-10706-x |
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Sci Rep |
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9068624/ http://dx.doi.org/10.1038/s41598-022-10706-x |
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© The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
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https://doi.org/10.1038/s41598-022-10706-x |
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