Testing of a mobile heating facility to sanitize N-95 respirators against an enveloped respiratory virus
In the spring of 2020, the Alaska Native Tribal Health Consortium (ANTHC) designed and built a sanitizing treatment system to address shortages of filtering facepiece respirators (FFRs). The design criteria included sanitizing large numbers of FFRs, repeatedly achieving FFR fit test requirements, an...
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Online Access: | http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9037215/ http://www.ncbi.nlm.nih.gov/pubmed/35426356 https://doi.org/10.1080/22423982.2022.2064597 |
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ftpubmed:oai:pubmedcentral.nih.gov:9037215 2023-05-15T15:55:23+02:00 Testing of a mobile heating facility to sanitize N-95 respirators against an enveloped respiratory virus Brubaker, Michael Fraser, William Cook, Keith Dagdag, Ralf Nelson, Abigail Warren, John Thomas, Timothy Lovejoy, Elle Kosten, Thomas Maniaci, Brandon Bortz, Eric Gray, Jacob 2022-04-15 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9037215/ http://www.ncbi.nlm.nih.gov/pubmed/35426356 https://doi.org/10.1080/22423982.2022.2064597 en eng Taylor & Francis http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9037215/ http://www.ncbi.nlm.nih.gov/pubmed/35426356 http://dx.doi.org/10.1080/22423982.2022.2064597 © 2022 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group. https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) ), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. CC-BY-NC Int J Circumpolar Health Original Research Article Text 2022 ftpubmed https://doi.org/10.1080/22423982.2022.2064597 2022-05-01T00:46:00Z In the spring of 2020, the Alaska Native Tribal Health Consortium (ANTHC) designed and built a sanitizing treatment system to address shortages of filtering facepiece respirators (FFRs). The design criteria included sanitizing large numbers of FFRs, repeatedly achieving FFR fit test requirements, and deactivating enveloped respiratory viruses, such as SARS-CoV-2. The outcome was the Mobile Sanitizing Trailer (MST), a 20 by 8-foot modified trailer designed to process up to 1,000 FFRs during a standard heat cycle. This paper reports on the MST’s ability to: (1) sustain a target temperature, (2) produce tolerable conditions for FFRs as measured by fit factor and (3) successfully deactivate an infectious model virus. We found that the MST reliably and uniformly produced 75 degrees Celsius in the treatment chamber for the prescribed periods. Quantitative analysis showed that the FFRs achieved acceptable post-treatment fit factor even after 18, 60-minute heat cycles. Finally, the treated FFR materials had at least a log 3.0 reduction in viral RNA and no viable virus after 30, 60 or 90 minutes of heat treatment. As a sanitizing treatment during supply shortages, we found the MST a viable option for deactivation of virus and extending the usable life of FFRs. Text Circumpolar Health Alaska PubMed Central (PMC) International Journal of Circumpolar Health 81 1 |
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English |
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Original Research Article |
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Original Research Article Brubaker, Michael Fraser, William Cook, Keith Dagdag, Ralf Nelson, Abigail Warren, John Thomas, Timothy Lovejoy, Elle Kosten, Thomas Maniaci, Brandon Bortz, Eric Gray, Jacob Testing of a mobile heating facility to sanitize N-95 respirators against an enveloped respiratory virus |
topic_facet |
Original Research Article |
description |
In the spring of 2020, the Alaska Native Tribal Health Consortium (ANTHC) designed and built a sanitizing treatment system to address shortages of filtering facepiece respirators (FFRs). The design criteria included sanitizing large numbers of FFRs, repeatedly achieving FFR fit test requirements, and deactivating enveloped respiratory viruses, such as SARS-CoV-2. The outcome was the Mobile Sanitizing Trailer (MST), a 20 by 8-foot modified trailer designed to process up to 1,000 FFRs during a standard heat cycle. This paper reports on the MST’s ability to: (1) sustain a target temperature, (2) produce tolerable conditions for FFRs as measured by fit factor and (3) successfully deactivate an infectious model virus. We found that the MST reliably and uniformly produced 75 degrees Celsius in the treatment chamber for the prescribed periods. Quantitative analysis showed that the FFRs achieved acceptable post-treatment fit factor even after 18, 60-minute heat cycles. Finally, the treated FFR materials had at least a log 3.0 reduction in viral RNA and no viable virus after 30, 60 or 90 minutes of heat treatment. As a sanitizing treatment during supply shortages, we found the MST a viable option for deactivation of virus and extending the usable life of FFRs. |
format |
Text |
author |
Brubaker, Michael Fraser, William Cook, Keith Dagdag, Ralf Nelson, Abigail Warren, John Thomas, Timothy Lovejoy, Elle Kosten, Thomas Maniaci, Brandon Bortz, Eric Gray, Jacob |
author_facet |
Brubaker, Michael Fraser, William Cook, Keith Dagdag, Ralf Nelson, Abigail Warren, John Thomas, Timothy Lovejoy, Elle Kosten, Thomas Maniaci, Brandon Bortz, Eric Gray, Jacob |
author_sort |
Brubaker, Michael |
title |
Testing of a mobile heating facility to sanitize N-95 respirators against an enveloped respiratory virus |
title_short |
Testing of a mobile heating facility to sanitize N-95 respirators against an enveloped respiratory virus |
title_full |
Testing of a mobile heating facility to sanitize N-95 respirators against an enveloped respiratory virus |
title_fullStr |
Testing of a mobile heating facility to sanitize N-95 respirators against an enveloped respiratory virus |
title_full_unstemmed |
Testing of a mobile heating facility to sanitize N-95 respirators against an enveloped respiratory virus |
title_sort |
testing of a mobile heating facility to sanitize n-95 respirators against an enveloped respiratory virus |
publisher |
Taylor & Francis |
publishDate |
2022 |
url |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9037215/ http://www.ncbi.nlm.nih.gov/pubmed/35426356 https://doi.org/10.1080/22423982.2022.2064597 |
genre |
Circumpolar Health Alaska |
genre_facet |
Circumpolar Health Alaska |
op_source |
Int J Circumpolar Health |
op_relation |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9037215/ http://www.ncbi.nlm.nih.gov/pubmed/35426356 http://dx.doi.org/10.1080/22423982.2022.2064597 |
op_rights |
© 2022 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group. https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) ), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
op_rightsnorm |
CC-BY-NC |
op_doi |
https://doi.org/10.1080/22423982.2022.2064597 |
container_title |
International Journal of Circumpolar Health |
container_volume |
81 |
container_issue |
1 |
_version_ |
1766390880848052224 |