Heat Stress Decreases Intestinal Physiological Function and Facilitates the Proliferation of Harmful Intestinal Microbiota in Sturgeons
Heat is a common source of stress in aquatic environments and can alter the physiological and metabolic functions of aquatic animals, especially their intestinal function. Here, the effects of heat stress on the structure and function of the intestine and the characteristics of the intestinal microb...
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ftpubmed:oai:pubmedcentral.nih.gov:8959899 2023-05-15T13:01:54+02:00 Heat Stress Decreases Intestinal Physiological Function and Facilitates the Proliferation of Harmful Intestinal Microbiota in Sturgeons Yang, Shiyong Zhang, Chaoyang Xu, Wenqiang Li, Datian Feng, Yang Wu, Jiayun Luo, Wei Du, Xiaogang Du, Zongjun Huang, Xiaoli 2022-03-07 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8959899/ http://www.ncbi.nlm.nih.gov/pubmed/35356512 https://doi.org/10.3389/fmicb.2022.755369 en eng Frontiers Media S.A. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8959899/ http://www.ncbi.nlm.nih.gov/pubmed/35356512 http://dx.doi.org/10.3389/fmicb.2022.755369 Copyright © 2022 Yang, Zhang, Xu, Li, Feng, Wu, Luo, Du, Du and Huang. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. CC-BY Front Microbiol Microbiology Text 2022 ftpubmed https://doi.org/10.3389/fmicb.2022.755369 2022-04-03T01:06:55Z Heat is a common source of stress in aquatic environments and can alter the physiological and metabolic functions of aquatic animals, especially their intestinal function. Here, the effects of heat stress on the structure and function of the intestine and the characteristics of the intestinal microbiota were studied in sturgeon (Acipenser baerii ♀ × Acipenser schrenckii ♂ hybrid F1). Sturgeons were exposed to sub-extreme (24°C) and extreme (28°C) high water temperatures for 12 days. The heat stress caused systemic damage to the intestine of sturgeons, which displayed severe enteritis in the valve intestine. The microbial diversity analysis showed that heat stress led to the disorder in intestinal microbiota, manifesting as an explosive increase in the abundance of thermophilic intestinal pathogens such as Plesiomonas, Cetobacterium, and Aeromonas and causing physiological dysfunction in the sturgeons. The disorder was followed by significant inhibition of intestinal digestion with reduced chymotrypsin, α-amylase, and lipase activities in the valve intestine and of antioxidant function with reduced peroxidase (POD) and catalase (CAT) activities. Simultaneously, heat stress reduced the thermal tolerance of sturgeons by reducing Grp75 expression and damaged the valve intestine’s repair ability with increased Tgf-β expression. The results confirmed that heat stress damaged the sturgeon intestines obviously and disturbed the intestinal microbiota, resulting in serious physiological dysfunction. The present study investigated the mechanism of the effect of heat stress on the sturgeon intestine and will help develop strategies to improve the resistance to thermal stress for wild and cultured sturgeons. Text Acipenser baerii PubMed Central (PMC) Frontiers in Microbiology 13 |
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PubMed Central (PMC) |
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English |
topic |
Microbiology |
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Microbiology Yang, Shiyong Zhang, Chaoyang Xu, Wenqiang Li, Datian Feng, Yang Wu, Jiayun Luo, Wei Du, Xiaogang Du, Zongjun Huang, Xiaoli Heat Stress Decreases Intestinal Physiological Function and Facilitates the Proliferation of Harmful Intestinal Microbiota in Sturgeons |
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Microbiology |
description |
Heat is a common source of stress in aquatic environments and can alter the physiological and metabolic functions of aquatic animals, especially their intestinal function. Here, the effects of heat stress on the structure and function of the intestine and the characteristics of the intestinal microbiota were studied in sturgeon (Acipenser baerii ♀ × Acipenser schrenckii ♂ hybrid F1). Sturgeons were exposed to sub-extreme (24°C) and extreme (28°C) high water temperatures for 12 days. The heat stress caused systemic damage to the intestine of sturgeons, which displayed severe enteritis in the valve intestine. The microbial diversity analysis showed that heat stress led to the disorder in intestinal microbiota, manifesting as an explosive increase in the abundance of thermophilic intestinal pathogens such as Plesiomonas, Cetobacterium, and Aeromonas and causing physiological dysfunction in the sturgeons. The disorder was followed by significant inhibition of intestinal digestion with reduced chymotrypsin, α-amylase, and lipase activities in the valve intestine and of antioxidant function with reduced peroxidase (POD) and catalase (CAT) activities. Simultaneously, heat stress reduced the thermal tolerance of sturgeons by reducing Grp75 expression and damaged the valve intestine’s repair ability with increased Tgf-β expression. The results confirmed that heat stress damaged the sturgeon intestines obviously and disturbed the intestinal microbiota, resulting in serious physiological dysfunction. The present study investigated the mechanism of the effect of heat stress on the sturgeon intestine and will help develop strategies to improve the resistance to thermal stress for wild and cultured sturgeons. |
format |
Text |
author |
Yang, Shiyong Zhang, Chaoyang Xu, Wenqiang Li, Datian Feng, Yang Wu, Jiayun Luo, Wei Du, Xiaogang Du, Zongjun Huang, Xiaoli |
author_facet |
Yang, Shiyong Zhang, Chaoyang Xu, Wenqiang Li, Datian Feng, Yang Wu, Jiayun Luo, Wei Du, Xiaogang Du, Zongjun Huang, Xiaoli |
author_sort |
Yang, Shiyong |
title |
Heat Stress Decreases Intestinal Physiological Function and Facilitates the Proliferation of Harmful Intestinal Microbiota in Sturgeons |
title_short |
Heat Stress Decreases Intestinal Physiological Function and Facilitates the Proliferation of Harmful Intestinal Microbiota in Sturgeons |
title_full |
Heat Stress Decreases Intestinal Physiological Function and Facilitates the Proliferation of Harmful Intestinal Microbiota in Sturgeons |
title_fullStr |
Heat Stress Decreases Intestinal Physiological Function and Facilitates the Proliferation of Harmful Intestinal Microbiota in Sturgeons |
title_full_unstemmed |
Heat Stress Decreases Intestinal Physiological Function and Facilitates the Proliferation of Harmful Intestinal Microbiota in Sturgeons |
title_sort |
heat stress decreases intestinal physiological function and facilitates the proliferation of harmful intestinal microbiota in sturgeons |
publisher |
Frontiers Media S.A. |
publishDate |
2022 |
url |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8959899/ http://www.ncbi.nlm.nih.gov/pubmed/35356512 https://doi.org/10.3389/fmicb.2022.755369 |
genre |
Acipenser baerii |
genre_facet |
Acipenser baerii |
op_source |
Front Microbiol |
op_relation |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8959899/ http://www.ncbi.nlm.nih.gov/pubmed/35356512 http://dx.doi.org/10.3389/fmicb.2022.755369 |
op_rights |
Copyright © 2022 Yang, Zhang, Xu, Li, Feng, Wu, Luo, Du, Du and Huang. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
op_rightsnorm |
CC-BY |
op_doi |
https://doi.org/10.3389/fmicb.2022.755369 |
container_title |
Frontiers in Microbiology |
container_volume |
13 |
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1766289786047299584 |