Acute COVID-19 severity and mental health morbidity trajectories in patient populations of six nations: an observational study
BACKGROUND: Long-term mental and physical health consequences of COVID-19 (long COVID) are a persistent public health concern. Little is still known about the long-term mental health of non-hospitalised patients with COVID-19 with varying illness severities. Our aim was to assess the prevalence of a...
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ftpubmed:oai:pubmedcentral.nih.gov:8920517 2023-05-15T16:52:47+02:00 Acute COVID-19 severity and mental health morbidity trajectories in patient populations of six nations: an observational study Magnúsdóttir, Ingibjörg Lovik, Anikó Unnarsdóttir, Anna Bára McCartney, Daniel Ask, Helga Kõiv, Kadri Christoffersen, Lea Arregui Nordahl Johnson, Sverre Urnes Hauksdóttir, Arna Fawns-Ritchie, Chloe Helenius, Dorte González-Hijón, Juan Lu, Li Ebrahimi, Omid V Hoffart, Asle Porteous, David J Fang, Fang Jakobsdóttir, Jóhanna Lehto, Kelli Andreassen, Ole A Pedersen, Ole B V Aspelund, Thor Valdimarsdóttir, Unnur Anna 2022-03-14 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8920517/ https://doi.org/10.1016/S2468-2667(22)00042-1 en eng The Author(s). Published by Elsevier Ltd. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8920517/ http://dx.doi.org/10.1016/S2468-2667(22)00042-1 © 2022 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY-NC-ND 4.0 license Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active. CC-BY-NC-ND Lancet Public Health Articles Text 2022 ftpubmed https://doi.org/10.1016/S2468-2667(22)00042-1 2022-03-20T01:46:04Z BACKGROUND: Long-term mental and physical health consequences of COVID-19 (long COVID) are a persistent public health concern. Little is still known about the long-term mental health of non-hospitalised patients with COVID-19 with varying illness severities. Our aim was to assess the prevalence of adverse mental health symptoms among individuals diagnosed with COVID-19 in the general population by acute infection severity up to 16 months after diagnosis. METHODS: This observational follow-up study included seven prospectively planned cohorts across six countries (Denmark, Estonia, Iceland, Norway, Sweden, and the UK). Participants were recruited from March 27, 2020, to Aug 13, 2021. Individuals aged 18 years or older were eligible to participate. In a cross-sectional analysis, we contrasted symptom prevalence of depression, anxiety, COVID-19-related distress, and poor sleep quality (screened with validated mental health instruments) among individuals with and without a diagnosis of COVID-19 at entry, 0–16 months from diagnosis. In a cohort analysis, we further used repeated measures to estimate the change in mental health symptoms before and after COVID-19 diagnosis. FINDINGS: The analytical cohort consisted of 247 249 individuals, 9979 (4·0%) of whom were diagnosed with COVID-19 during the study period. Mean follow-up was 5·65 months (SD 4·26). Participants diagnosed with COVID-19 presented overall with a higher prevalence of symptoms of depression (prevalence ratio [PR] 1·18 [95% CI 1·03–1·36]) and poorer sleep quality (1·13 [1·03–1·24]) but not symptoms of anxiety (0·97 [0·91–1·03]) or COVID-19-related distress (1·05 [0·93–1·20]) compared with individuals without a COVID-19 diagnosis. Although the prevalence of depression and COVID-19-related distress attenuated with time, individuals diagnosed with COVID-19 but never bedridden due to their illness were consistently at lower risk of depression (PR 0·83 [95% CI 0·75–0·91]) and anxiety (0·77 [0·63–0·94]) than those not diagnosed with COVID-19, whereas patients ... Text Iceland PubMed Central (PMC) Norway The Lancet Public Health |
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Articles Magnúsdóttir, Ingibjörg Lovik, Anikó Unnarsdóttir, Anna Bára McCartney, Daniel Ask, Helga Kõiv, Kadri Christoffersen, Lea Arregui Nordahl Johnson, Sverre Urnes Hauksdóttir, Arna Fawns-Ritchie, Chloe Helenius, Dorte González-Hijón, Juan Lu, Li Ebrahimi, Omid V Hoffart, Asle Porteous, David J Fang, Fang Jakobsdóttir, Jóhanna Lehto, Kelli Andreassen, Ole A Pedersen, Ole B V Aspelund, Thor Valdimarsdóttir, Unnur Anna Acute COVID-19 severity and mental health morbidity trajectories in patient populations of six nations: an observational study |
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Articles |
description |
BACKGROUND: Long-term mental and physical health consequences of COVID-19 (long COVID) are a persistent public health concern. Little is still known about the long-term mental health of non-hospitalised patients with COVID-19 with varying illness severities. Our aim was to assess the prevalence of adverse mental health symptoms among individuals diagnosed with COVID-19 in the general population by acute infection severity up to 16 months after diagnosis. METHODS: This observational follow-up study included seven prospectively planned cohorts across six countries (Denmark, Estonia, Iceland, Norway, Sweden, and the UK). Participants were recruited from March 27, 2020, to Aug 13, 2021. Individuals aged 18 years or older were eligible to participate. In a cross-sectional analysis, we contrasted symptom prevalence of depression, anxiety, COVID-19-related distress, and poor sleep quality (screened with validated mental health instruments) among individuals with and without a diagnosis of COVID-19 at entry, 0–16 months from diagnosis. In a cohort analysis, we further used repeated measures to estimate the change in mental health symptoms before and after COVID-19 diagnosis. FINDINGS: The analytical cohort consisted of 247 249 individuals, 9979 (4·0%) of whom were diagnosed with COVID-19 during the study period. Mean follow-up was 5·65 months (SD 4·26). Participants diagnosed with COVID-19 presented overall with a higher prevalence of symptoms of depression (prevalence ratio [PR] 1·18 [95% CI 1·03–1·36]) and poorer sleep quality (1·13 [1·03–1·24]) but not symptoms of anxiety (0·97 [0·91–1·03]) or COVID-19-related distress (1·05 [0·93–1·20]) compared with individuals without a COVID-19 diagnosis. Although the prevalence of depression and COVID-19-related distress attenuated with time, individuals diagnosed with COVID-19 but never bedridden due to their illness were consistently at lower risk of depression (PR 0·83 [95% CI 0·75–0·91]) and anxiety (0·77 [0·63–0·94]) than those not diagnosed with COVID-19, whereas patients ... |
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Text |
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Magnúsdóttir, Ingibjörg Lovik, Anikó Unnarsdóttir, Anna Bára McCartney, Daniel Ask, Helga Kõiv, Kadri Christoffersen, Lea Arregui Nordahl Johnson, Sverre Urnes Hauksdóttir, Arna Fawns-Ritchie, Chloe Helenius, Dorte González-Hijón, Juan Lu, Li Ebrahimi, Omid V Hoffart, Asle Porteous, David J Fang, Fang Jakobsdóttir, Jóhanna Lehto, Kelli Andreassen, Ole A Pedersen, Ole B V Aspelund, Thor Valdimarsdóttir, Unnur Anna |
author_facet |
Magnúsdóttir, Ingibjörg Lovik, Anikó Unnarsdóttir, Anna Bára McCartney, Daniel Ask, Helga Kõiv, Kadri Christoffersen, Lea Arregui Nordahl Johnson, Sverre Urnes Hauksdóttir, Arna Fawns-Ritchie, Chloe Helenius, Dorte González-Hijón, Juan Lu, Li Ebrahimi, Omid V Hoffart, Asle Porteous, David J Fang, Fang Jakobsdóttir, Jóhanna Lehto, Kelli Andreassen, Ole A Pedersen, Ole B V Aspelund, Thor Valdimarsdóttir, Unnur Anna |
author_sort |
Magnúsdóttir, Ingibjörg |
title |
Acute COVID-19 severity and mental health morbidity trajectories in patient populations of six nations: an observational study |
title_short |
Acute COVID-19 severity and mental health morbidity trajectories in patient populations of six nations: an observational study |
title_full |
Acute COVID-19 severity and mental health morbidity trajectories in patient populations of six nations: an observational study |
title_fullStr |
Acute COVID-19 severity and mental health morbidity trajectories in patient populations of six nations: an observational study |
title_full_unstemmed |
Acute COVID-19 severity and mental health morbidity trajectories in patient populations of six nations: an observational study |
title_sort |
acute covid-19 severity and mental health morbidity trajectories in patient populations of six nations: an observational study |
publisher |
The Author(s). Published by Elsevier Ltd. |
publishDate |
2022 |
url |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8920517/ https://doi.org/10.1016/S2468-2667(22)00042-1 |
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Norway |
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Norway |
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Iceland |
op_source |
Lancet Public Health |
op_relation |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8920517/ http://dx.doi.org/10.1016/S2468-2667(22)00042-1 |
op_rights |
© 2022 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY-NC-ND 4.0 license Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active. |
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CC-BY-NC-ND |
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https://doi.org/10.1016/S2468-2667(22)00042-1 |
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The Lancet Public Health |
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