Rhythmic Clock Gene Expression in Atlantic Salmon Parr Brain
To better understand the complexity of clock genes in salmonids, a taxon with an additional whole genome duplication, an analysis was performed to identify and classify gene family members (clock, arntl, period, cryptochrome, nr1d, ror, and csnk1). The majority of clock genes, in zebrafish and North...
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ftpubmed:oai:pubmedcentral.nih.gov:8674837 2023-05-15T15:31:18+02:00 Rhythmic Clock Gene Expression in Atlantic Salmon Parr Brain Bolton, Charlotte M. Bekaert, Michaël Eilertsen, Mariann Helvik, Jon Vidar Migaud, Herve 2021-12-02 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8674837/ https://doi.org/10.3389/fphys.2021.761109 en eng Frontiers Media S.A. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8674837/ http://dx.doi.org/10.3389/fphys.2021.761109 Copyright © 2021 Bolton, Bekaert, Eilertsen, Helvik and Migaud. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. CC-BY Front Physiol Physiology Text 2021 ftpubmed https://doi.org/10.3389/fphys.2021.761109 2021-12-19T01:57:38Z To better understand the complexity of clock genes in salmonids, a taxon with an additional whole genome duplication, an analysis was performed to identify and classify gene family members (clock, arntl, period, cryptochrome, nr1d, ror, and csnk1). The majority of clock genes, in zebrafish and Northern pike, appeared to be duplicated. In comparison to the 29 clock genes described in zebrafish, 48 clock genes were discovered in salmonid species. There was also evidence of species-specific reciprocal gene losses conserved to the Oncorhynchus sister clade. From the six period genes identified three were highly significantly rhythmic, and circadian in their expression patterns (per1a.1, per1a.2, per1b) and two was significantly rhythmically expressed (per2a, per2b). The transcriptomic study of juvenile Atlantic salmon (parr) brain tissues confirmed gene identification and revealed that there were 2,864 rhythmically expressed genes (p < 0.001), including 1,215 genes with a circadian expression pattern, of which 11 were clock genes. The majority of circadian expressed genes peaked 2 h before and after daylight. These findings provide a foundation for further research into the function of clock genes circadian rhythmicity and the role of an enriched number of clock genes relating to seasonal driven life history in salmonids. Text Atlantic salmon PubMed Central (PMC) Frontiers in Physiology 12 |
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Physiology |
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Physiology Bolton, Charlotte M. Bekaert, Michaël Eilertsen, Mariann Helvik, Jon Vidar Migaud, Herve Rhythmic Clock Gene Expression in Atlantic Salmon Parr Brain |
topic_facet |
Physiology |
description |
To better understand the complexity of clock genes in salmonids, a taxon with an additional whole genome duplication, an analysis was performed to identify and classify gene family members (clock, arntl, period, cryptochrome, nr1d, ror, and csnk1). The majority of clock genes, in zebrafish and Northern pike, appeared to be duplicated. In comparison to the 29 clock genes described in zebrafish, 48 clock genes were discovered in salmonid species. There was also evidence of species-specific reciprocal gene losses conserved to the Oncorhynchus sister clade. From the six period genes identified three were highly significantly rhythmic, and circadian in their expression patterns (per1a.1, per1a.2, per1b) and two was significantly rhythmically expressed (per2a, per2b). The transcriptomic study of juvenile Atlantic salmon (parr) brain tissues confirmed gene identification and revealed that there were 2,864 rhythmically expressed genes (p < 0.001), including 1,215 genes with a circadian expression pattern, of which 11 were clock genes. The majority of circadian expressed genes peaked 2 h before and after daylight. These findings provide a foundation for further research into the function of clock genes circadian rhythmicity and the role of an enriched number of clock genes relating to seasonal driven life history in salmonids. |
format |
Text |
author |
Bolton, Charlotte M. Bekaert, Michaël Eilertsen, Mariann Helvik, Jon Vidar Migaud, Herve |
author_facet |
Bolton, Charlotte M. Bekaert, Michaël Eilertsen, Mariann Helvik, Jon Vidar Migaud, Herve |
author_sort |
Bolton, Charlotte M. |
title |
Rhythmic Clock Gene Expression in Atlantic Salmon Parr Brain |
title_short |
Rhythmic Clock Gene Expression in Atlantic Salmon Parr Brain |
title_full |
Rhythmic Clock Gene Expression in Atlantic Salmon Parr Brain |
title_fullStr |
Rhythmic Clock Gene Expression in Atlantic Salmon Parr Brain |
title_full_unstemmed |
Rhythmic Clock Gene Expression in Atlantic Salmon Parr Brain |
title_sort |
rhythmic clock gene expression in atlantic salmon parr brain |
publisher |
Frontiers Media S.A. |
publishDate |
2021 |
url |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8674837/ https://doi.org/10.3389/fphys.2021.761109 |
genre |
Atlantic salmon |
genre_facet |
Atlantic salmon |
op_source |
Front Physiol |
op_relation |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8674837/ http://dx.doi.org/10.3389/fphys.2021.761109 |
op_rights |
Copyright © 2021 Bolton, Bekaert, Eilertsen, Helvik and Migaud. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
op_rightsnorm |
CC-BY |
op_doi |
https://doi.org/10.3389/fphys.2021.761109 |
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Frontiers in Physiology |
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12 |
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