Temporally balanced selection during development of larval Pacific oysters (Crassostrea gigas) inherently preserves genetic diversity within offspring
Balancing selection is one of the mechanisms which has been proposed to explain the maintenance of genetic diversity in species across generations. For species with large populations and complex life histories, however, heterogeneous selection pressures may create a scenario in which the net effects...
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ftpubmed:oai:pubmedcentral.nih.gov:8437028 2023-05-15T15:57:47+02:00 Temporally balanced selection during development of larval Pacific oysters (Crassostrea gigas) inherently preserves genetic diversity within offspring Durland, Evan De Wit, Pierre Langdon, Chris 2021-09-08 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8437028/ http://www.ncbi.nlm.nih.gov/pubmed/34465244 https://doi.org/10.1098/rspb.2020.3223 en eng The Royal Society http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8437028/ http://www.ncbi.nlm.nih.gov/pubmed/34465244 http://dx.doi.org/10.1098/rspb.2020.3223 © 2021 The Authors. https://creativecommons.org/licenses/by/4.0/Published by the Royal Society under the terms of the Creative Commons Attribution License http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, provided the original author and source are credited. CC-BY Proc Biol Sci Genetics and Genomics Text 2021 ftpubmed https://doi.org/10.1098/rspb.2020.3223 2021-09-26T00:26:15Z Balancing selection is one of the mechanisms which has been proposed to explain the maintenance of genetic diversity in species across generations. For species with large populations and complex life histories, however, heterogeneous selection pressures may create a scenario in which the net effects of selection are balanced across developmental stages. With replicated cultures and a pooled sequencing approach, we show that genotype-dependent mortality in larvae of the Pacific oyster (Crassostrea gigas) is largely temporally dynamic and inconsistently in favour of a single genotype or allelic variant at each locus. Overall, the patterns of genetic change we observe to be taking place are more complex than what would be expected under classical examples of additive or dominant genetic interactions. They are also not easily explained by our current understanding of the effects of genetic load. Collectively, temporally heterogeneous selection pressures across different larval developmental stages may act to maintain genetic diversity, while also inherently sheltering genetic load within oyster populations. Text Crassostrea gigas Pacific oyster PubMed Central (PMC) Pacific Proceedings of the Royal Society B: Biological Sciences 288 1958 20203223 |
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English |
topic |
Genetics and Genomics |
spellingShingle |
Genetics and Genomics Durland, Evan De Wit, Pierre Langdon, Chris Temporally balanced selection during development of larval Pacific oysters (Crassostrea gigas) inherently preserves genetic diversity within offspring |
topic_facet |
Genetics and Genomics |
description |
Balancing selection is one of the mechanisms which has been proposed to explain the maintenance of genetic diversity in species across generations. For species with large populations and complex life histories, however, heterogeneous selection pressures may create a scenario in which the net effects of selection are balanced across developmental stages. With replicated cultures and a pooled sequencing approach, we show that genotype-dependent mortality in larvae of the Pacific oyster (Crassostrea gigas) is largely temporally dynamic and inconsistently in favour of a single genotype or allelic variant at each locus. Overall, the patterns of genetic change we observe to be taking place are more complex than what would be expected under classical examples of additive or dominant genetic interactions. They are also not easily explained by our current understanding of the effects of genetic load. Collectively, temporally heterogeneous selection pressures across different larval developmental stages may act to maintain genetic diversity, while also inherently sheltering genetic load within oyster populations. |
format |
Text |
author |
Durland, Evan De Wit, Pierre Langdon, Chris |
author_facet |
Durland, Evan De Wit, Pierre Langdon, Chris |
author_sort |
Durland, Evan |
title |
Temporally balanced selection during development of larval Pacific oysters (Crassostrea gigas) inherently preserves genetic diversity within offspring |
title_short |
Temporally balanced selection during development of larval Pacific oysters (Crassostrea gigas) inherently preserves genetic diversity within offspring |
title_full |
Temporally balanced selection during development of larval Pacific oysters (Crassostrea gigas) inherently preserves genetic diversity within offspring |
title_fullStr |
Temporally balanced selection during development of larval Pacific oysters (Crassostrea gigas) inherently preserves genetic diversity within offspring |
title_full_unstemmed |
Temporally balanced selection during development of larval Pacific oysters (Crassostrea gigas) inherently preserves genetic diversity within offspring |
title_sort |
temporally balanced selection during development of larval pacific oysters (crassostrea gigas) inherently preserves genetic diversity within offspring |
publisher |
The Royal Society |
publishDate |
2021 |
url |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8437028/ http://www.ncbi.nlm.nih.gov/pubmed/34465244 https://doi.org/10.1098/rspb.2020.3223 |
geographic |
Pacific |
geographic_facet |
Pacific |
genre |
Crassostrea gigas Pacific oyster |
genre_facet |
Crassostrea gigas Pacific oyster |
op_source |
Proc Biol Sci |
op_relation |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8437028/ http://www.ncbi.nlm.nih.gov/pubmed/34465244 http://dx.doi.org/10.1098/rspb.2020.3223 |
op_rights |
© 2021 The Authors. https://creativecommons.org/licenses/by/4.0/Published by the Royal Society under the terms of the Creative Commons Attribution License http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, provided the original author and source are credited. |
op_rightsnorm |
CC-BY |
op_doi |
https://doi.org/10.1098/rspb.2020.3223 |
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Proceedings of the Royal Society B: Biological Sciences |
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288 |
container_issue |
1958 |
container_start_page |
20203223 |
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1766393491989987328 |