Change in cardiovascular risk assessment tool and updated Norwegian guidelines for cardiovascular disease in primary prevention increase the population proportion at risk: the Tromsø Study 2015–2016
AIMS: To compare the population proportion at high risk of cardiovascular disease (CVD) using the Norwegian NORRISK 1 that predicts 10-year risk of CVD mortality and the Norwegian national guidelines from 2009, with the updated NORRISK 2 that predicts 10-year risk of both fatal and non-fatal risk of...
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Online Access: | http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8407203/ http://www.ncbi.nlm.nih.gov/pubmed/34462328 https://doi.org/10.1136/openhrt-2021-001777 |
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ftpubmed:oai:pubmedcentral.nih.gov:8407203 2023-05-15T18:34:28+02:00 Change in cardiovascular risk assessment tool and updated Norwegian guidelines for cardiovascular disease in primary prevention increase the population proportion at risk: the Tromsø Study 2015–2016 Nilsen, Amalie Hanssen, Tove Aminda Lappegård, Knut Tore Eggen, Anne Elise Løchen, Maja-Lisa Selmer, Randi Marie Njølstad, Inger Wilsgaard, Tom Hopstock, Laila A 2021-08-30 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8407203/ http://www.ncbi.nlm.nih.gov/pubmed/34462328 https://doi.org/10.1136/openhrt-2021-001777 en eng BMJ Publishing Group http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8407203/ http://www.ncbi.nlm.nih.gov/pubmed/34462328 http://dx.doi.org/10.1136/openhrt-2021-001777 © Author(s) (or their employer(s)) 2021. Re-use permitted under CC BY. Published by BMJ. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution 4.0 Unported (CC BY 4.0) license, which permits others to copy, redistribute, remix, transform and build upon this work for any purpose, provided the original work is properly cited, a link to the licence is given, and indication of whether changes were made. See: https://creativecommons.org/licenses/by/4.0/. CC-BY Open Heart Cardiac Risk Factors and Prevention Text 2021 ftpubmed https://doi.org/10.1136/openhrt-2021-001777 2021-09-19T00:26:36Z AIMS: To compare the population proportion at high risk of cardiovascular disease (CVD) using the Norwegian NORRISK 1 that predicts 10-year risk of CVD mortality and the Norwegian national guidelines from 2009, with the updated NORRISK 2 that predicts 10-year risk of both fatal and non-fatal risk of CVD and the Norwegian national guidelines from 2017. METHODS: We included participants from the Norwegian population-based Tromsø Study (2015–2016) aged 40–69 years without a history of CVD (n=16 566). The total proportion eligible for intervention was identified by NORRISK 1 and the 2009 guidelines (serum total cholesterol ≥8 mmol/L, systolic blood pressure ≥160 mm Hg or diastolic blood pressure ≥100 mm Hg) and NORRISK 2 and the 2017 guidelines (serum total cholesterol ≥7 mmol/L, low density lipoprotein (LDL) cholesterol ≥5 mmol/L, systolic blood pressure ≥160 mm Hg or diastolic blood pressure ≥100 mm Hg). RESULTS: The total proportion at high risk as defined by a risk score was 12.0% using NORRISK 1 and 9.8% using NORRISK 2. When including single risk factors specified by the guidelines, the total proportion eligible for intervention was 15.5% using NORRISK 1 and the 2009 guidelines and 18.9% using NORRISK 2 and the 2017 guidelines. The lowered threshold for total cholesterol and specified cut-off for LDL cholesterol stand for a large proportion of the increase in population at risk. CONCLUSION: The population proportion eligible for intervention increased by 3.4 percentage points from 2009 to 2017 using the revised NORRISK 2 score and guidelines. Text Tromsø PubMed Central (PMC) Tromsø Open Heart 8 2 e001777 |
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English |
topic |
Cardiac Risk Factors and Prevention |
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Cardiac Risk Factors and Prevention Nilsen, Amalie Hanssen, Tove Aminda Lappegård, Knut Tore Eggen, Anne Elise Løchen, Maja-Lisa Selmer, Randi Marie Njølstad, Inger Wilsgaard, Tom Hopstock, Laila A Change in cardiovascular risk assessment tool and updated Norwegian guidelines for cardiovascular disease in primary prevention increase the population proportion at risk: the Tromsø Study 2015–2016 |
topic_facet |
Cardiac Risk Factors and Prevention |
description |
AIMS: To compare the population proportion at high risk of cardiovascular disease (CVD) using the Norwegian NORRISK 1 that predicts 10-year risk of CVD mortality and the Norwegian national guidelines from 2009, with the updated NORRISK 2 that predicts 10-year risk of both fatal and non-fatal risk of CVD and the Norwegian national guidelines from 2017. METHODS: We included participants from the Norwegian population-based Tromsø Study (2015–2016) aged 40–69 years without a history of CVD (n=16 566). The total proportion eligible for intervention was identified by NORRISK 1 and the 2009 guidelines (serum total cholesterol ≥8 mmol/L, systolic blood pressure ≥160 mm Hg or diastolic blood pressure ≥100 mm Hg) and NORRISK 2 and the 2017 guidelines (serum total cholesterol ≥7 mmol/L, low density lipoprotein (LDL) cholesterol ≥5 mmol/L, systolic blood pressure ≥160 mm Hg or diastolic blood pressure ≥100 mm Hg). RESULTS: The total proportion at high risk as defined by a risk score was 12.0% using NORRISK 1 and 9.8% using NORRISK 2. When including single risk factors specified by the guidelines, the total proportion eligible for intervention was 15.5% using NORRISK 1 and the 2009 guidelines and 18.9% using NORRISK 2 and the 2017 guidelines. The lowered threshold for total cholesterol and specified cut-off for LDL cholesterol stand for a large proportion of the increase in population at risk. CONCLUSION: The population proportion eligible for intervention increased by 3.4 percentage points from 2009 to 2017 using the revised NORRISK 2 score and guidelines. |
format |
Text |
author |
Nilsen, Amalie Hanssen, Tove Aminda Lappegård, Knut Tore Eggen, Anne Elise Løchen, Maja-Lisa Selmer, Randi Marie Njølstad, Inger Wilsgaard, Tom Hopstock, Laila A |
author_facet |
Nilsen, Amalie Hanssen, Tove Aminda Lappegård, Knut Tore Eggen, Anne Elise Løchen, Maja-Lisa Selmer, Randi Marie Njølstad, Inger Wilsgaard, Tom Hopstock, Laila A |
author_sort |
Nilsen, Amalie |
title |
Change in cardiovascular risk assessment tool and updated Norwegian guidelines for cardiovascular disease in primary prevention increase the population proportion at risk: the Tromsø Study 2015–2016 |
title_short |
Change in cardiovascular risk assessment tool and updated Norwegian guidelines for cardiovascular disease in primary prevention increase the population proportion at risk: the Tromsø Study 2015–2016 |
title_full |
Change in cardiovascular risk assessment tool and updated Norwegian guidelines for cardiovascular disease in primary prevention increase the population proportion at risk: the Tromsø Study 2015–2016 |
title_fullStr |
Change in cardiovascular risk assessment tool and updated Norwegian guidelines for cardiovascular disease in primary prevention increase the population proportion at risk: the Tromsø Study 2015–2016 |
title_full_unstemmed |
Change in cardiovascular risk assessment tool and updated Norwegian guidelines for cardiovascular disease in primary prevention increase the population proportion at risk: the Tromsø Study 2015–2016 |
title_sort |
change in cardiovascular risk assessment tool and updated norwegian guidelines for cardiovascular disease in primary prevention increase the population proportion at risk: the tromsø study 2015–2016 |
publisher |
BMJ Publishing Group |
publishDate |
2021 |
url |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8407203/ http://www.ncbi.nlm.nih.gov/pubmed/34462328 https://doi.org/10.1136/openhrt-2021-001777 |
geographic |
Tromsø |
geographic_facet |
Tromsø |
genre |
Tromsø |
genre_facet |
Tromsø |
op_source |
Open Heart |
op_relation |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8407203/ http://www.ncbi.nlm.nih.gov/pubmed/34462328 http://dx.doi.org/10.1136/openhrt-2021-001777 |
op_rights |
© Author(s) (or their employer(s)) 2021. Re-use permitted under CC BY. Published by BMJ. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution 4.0 Unported (CC BY 4.0) license, which permits others to copy, redistribute, remix, transform and build upon this work for any purpose, provided the original work is properly cited, a link to the licence is given, and indication of whether changes were made. See: https://creativecommons.org/licenses/by/4.0/. |
op_rightsnorm |
CC-BY |
op_doi |
https://doi.org/10.1136/openhrt-2021-001777 |
container_title |
Open Heart |
container_volume |
8 |
container_issue |
2 |
container_start_page |
e001777 |
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1766219225644400640 |