Cold Adaptation Strategies and the Potential of Psychrophilic Enzymes from the Antarctic Yeast, Glaciozyma antarctica PI12
Psychrophilic organisms possess several adaptive strategies which allow them to sustain life at low temperatures between −20 to 20 °C. Studies on Antarctic psychrophiles are interesting due to the multiple stressors that exist on the permanently cold continent. These organisms produce, among other p...
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ftpubmed:oai:pubmedcentral.nih.gov:8306469 2023-05-15T13:56:57+02:00 Cold Adaptation Strategies and the Potential of Psychrophilic Enzymes from the Antarctic Yeast, Glaciozyma antarctica PI12 Yusof, Nur Athirah Hashim, Noor Haza Fazlin Bharudin, Izwan 2021-06-30 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8306469/ http://www.ncbi.nlm.nih.gov/pubmed/34209103 https://doi.org/10.3390/jof7070528 en eng MDPI http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8306469/ http://www.ncbi.nlm.nih.gov/pubmed/34209103 http://dx.doi.org/10.3390/jof7070528 © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). CC-BY J Fungi (Basel) Review Text 2021 ftpubmed https://doi.org/10.3390/jof7070528 2021-08-01T00:40:42Z Psychrophilic organisms possess several adaptive strategies which allow them to sustain life at low temperatures between −20 to 20 °C. Studies on Antarctic psychrophiles are interesting due to the multiple stressors that exist on the permanently cold continent. These organisms produce, among other peculiarities, cold-active enzymes which not only have tremendous biotechnological potential but are valuable models for fundamental research into protein structure and function. Recent innovations in omics technologies such as genomics, transcriptomics, proteomics and metabolomics have contributed a remarkable perspective of the molecular basis underpinning the mechanisms of cold adaptation. This review critically discusses similar and different strategies of cold adaptation in the obligate psychrophilic yeast, Glaciozyma antarctica PI12 at the molecular (genome structure, proteins and enzymes, gene expression) and physiological (antifreeze proteins, membrane fluidity, stress-related proteins) levels. Our extensive studies on G. antarctica have revealed significant insights towards the innate capacity of- and the adaptation strategies employed by this psychrophilic yeast for life in the persistent cold. Furthermore, several cold-active enzymes and proteins with biotechnological potential are also discussed. Text Antarc* Antarctic Antarctica PubMed Central (PMC) Antarctic The Antarctic Journal of Fungi 7 7 528 |
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Review Yusof, Nur Athirah Hashim, Noor Haza Fazlin Bharudin, Izwan Cold Adaptation Strategies and the Potential of Psychrophilic Enzymes from the Antarctic Yeast, Glaciozyma antarctica PI12 |
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Review |
description |
Psychrophilic organisms possess several adaptive strategies which allow them to sustain life at low temperatures between −20 to 20 °C. Studies on Antarctic psychrophiles are interesting due to the multiple stressors that exist on the permanently cold continent. These organisms produce, among other peculiarities, cold-active enzymes which not only have tremendous biotechnological potential but are valuable models for fundamental research into protein structure and function. Recent innovations in omics technologies such as genomics, transcriptomics, proteomics and metabolomics have contributed a remarkable perspective of the molecular basis underpinning the mechanisms of cold adaptation. This review critically discusses similar and different strategies of cold adaptation in the obligate psychrophilic yeast, Glaciozyma antarctica PI12 at the molecular (genome structure, proteins and enzymes, gene expression) and physiological (antifreeze proteins, membrane fluidity, stress-related proteins) levels. Our extensive studies on G. antarctica have revealed significant insights towards the innate capacity of- and the adaptation strategies employed by this psychrophilic yeast for life in the persistent cold. Furthermore, several cold-active enzymes and proteins with biotechnological potential are also discussed. |
format |
Text |
author |
Yusof, Nur Athirah Hashim, Noor Haza Fazlin Bharudin, Izwan |
author_facet |
Yusof, Nur Athirah Hashim, Noor Haza Fazlin Bharudin, Izwan |
author_sort |
Yusof, Nur Athirah |
title |
Cold Adaptation Strategies and the Potential of Psychrophilic Enzymes from the Antarctic Yeast, Glaciozyma antarctica PI12 |
title_short |
Cold Adaptation Strategies and the Potential of Psychrophilic Enzymes from the Antarctic Yeast, Glaciozyma antarctica PI12 |
title_full |
Cold Adaptation Strategies and the Potential of Psychrophilic Enzymes from the Antarctic Yeast, Glaciozyma antarctica PI12 |
title_fullStr |
Cold Adaptation Strategies and the Potential of Psychrophilic Enzymes from the Antarctic Yeast, Glaciozyma antarctica PI12 |
title_full_unstemmed |
Cold Adaptation Strategies and the Potential of Psychrophilic Enzymes from the Antarctic Yeast, Glaciozyma antarctica PI12 |
title_sort |
cold adaptation strategies and the potential of psychrophilic enzymes from the antarctic yeast, glaciozyma antarctica pi12 |
publisher |
MDPI |
publishDate |
2021 |
url |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8306469/ http://www.ncbi.nlm.nih.gov/pubmed/34209103 https://doi.org/10.3390/jof7070528 |
geographic |
Antarctic The Antarctic |
geographic_facet |
Antarctic The Antarctic |
genre |
Antarc* Antarctic Antarctica |
genre_facet |
Antarc* Antarctic Antarctica |
op_source |
J Fungi (Basel) |
op_relation |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8306469/ http://www.ncbi.nlm.nih.gov/pubmed/34209103 http://dx.doi.org/10.3390/jof7070528 |
op_rights |
© 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
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CC-BY |
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https://doi.org/10.3390/jof7070528 |
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Journal of Fungi |
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7 |
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7 |
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528 |
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1766264557355925504 |