Reference Values for DXA-Derived Visceral Adipose Tissue in Adults 40 Years and Older from a European Population: The Tromsø Study 2015–2016
BACKGROUND: Reference values for visceral adipose tissue (VAT) are needed and it has been advocated that body composition measures depend on both the technique and methods applied, as well as the population of interest. We aimed to develop reference values for VAT in absolute grams (VATg), percent (...
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ftpubmed:oai:pubmedcentral.nih.gov:8147540 2023-05-15T18:34:29+02:00 Reference Values for DXA-Derived Visceral Adipose Tissue in Adults 40 Years and Older from a European Population: The Tromsø Study 2015–2016 Lundblad, Marie W. Jacobsen, Bjarne K. Johansson, Jonas De Lucia Rolfe, Emanuella Grimsgaard, Sameline Hopstock, Laila A. 2021-05-15 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8147540/ https://doi.org/10.1155/2021/6634536 en eng Hindawi http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8147540/ http://dx.doi.org/10.1155/2021/6634536 Copyright © 2021 Marie W. Lundblad et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. CC-BY J Obes Research Article Text 2021 ftpubmed https://doi.org/10.1155/2021/6634536 2021-05-30T00:52:53Z BACKGROUND: Reference values for visceral adipose tissue (VAT) are needed and it has been advocated that body composition measures depend on both the technique and methods applied, as well as the population of interest. We aimed to develop reference values for VAT in absolute grams (VATg), percent (VAT%), and as a kilogram-per-meters-squared index (VATindex) for women and men, and investigate potential differences between these measures and their associations with cardiometabolic risk factors (including metabolic syndrome (MetS)). METHODS: In the seventh survey of the population-based Tromsø Study, 3675 participants (aged 40–84, 59% women) attended whole-body DXA scans (Lunar Prodigy GE) from where VAT was derived. We used descriptive analysis, correlations, receiver operating characteristics (ROC), and logistic regression to propose reference values for VAT and investigated VAT's association with cardiometabolic risk factors, MetS and single MetS components. Further, Youden's index was used to suggest threshold values for VAT. RESULTS: VATg and VATindex increased until age 70 and then decreased, while VAT% increased with age across all age groups. VAT (all measurement units) was moderate to highly correlated and significantly associated with all cardiometabolic risk factors, except for total cholesterol. Associations between MetS, single MetS components, and VATg and VATindex were similar, and VAT% did not contribute any further to this association. CONCLUSION: These VAT reference values and thresholds, developed in a sample of adults of Norwegian origin, could be applied to other studies with similar populations using the same DXA device and protocols. The associations between VAT and cardiometabolic risk factors were similar across different measurement units of VAT. Text Tromsø PubMed Central (PMC) Tromsø Journal of Obesity 2021 1 10 |
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Research Article Lundblad, Marie W. Jacobsen, Bjarne K. Johansson, Jonas De Lucia Rolfe, Emanuella Grimsgaard, Sameline Hopstock, Laila A. Reference Values for DXA-Derived Visceral Adipose Tissue in Adults 40 Years and Older from a European Population: The Tromsø Study 2015–2016 |
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Research Article |
description |
BACKGROUND: Reference values for visceral adipose tissue (VAT) are needed and it has been advocated that body composition measures depend on both the technique and methods applied, as well as the population of interest. We aimed to develop reference values for VAT in absolute grams (VATg), percent (VAT%), and as a kilogram-per-meters-squared index (VATindex) for women and men, and investigate potential differences between these measures and their associations with cardiometabolic risk factors (including metabolic syndrome (MetS)). METHODS: In the seventh survey of the population-based Tromsø Study, 3675 participants (aged 40–84, 59% women) attended whole-body DXA scans (Lunar Prodigy GE) from where VAT was derived. We used descriptive analysis, correlations, receiver operating characteristics (ROC), and logistic regression to propose reference values for VAT and investigated VAT's association with cardiometabolic risk factors, MetS and single MetS components. Further, Youden's index was used to suggest threshold values for VAT. RESULTS: VATg and VATindex increased until age 70 and then decreased, while VAT% increased with age across all age groups. VAT (all measurement units) was moderate to highly correlated and significantly associated with all cardiometabolic risk factors, except for total cholesterol. Associations between MetS, single MetS components, and VATg and VATindex were similar, and VAT% did not contribute any further to this association. CONCLUSION: These VAT reference values and thresholds, developed in a sample of adults of Norwegian origin, could be applied to other studies with similar populations using the same DXA device and protocols. The associations between VAT and cardiometabolic risk factors were similar across different measurement units of VAT. |
format |
Text |
author |
Lundblad, Marie W. Jacobsen, Bjarne K. Johansson, Jonas De Lucia Rolfe, Emanuella Grimsgaard, Sameline Hopstock, Laila A. |
author_facet |
Lundblad, Marie W. Jacobsen, Bjarne K. Johansson, Jonas De Lucia Rolfe, Emanuella Grimsgaard, Sameline Hopstock, Laila A. |
author_sort |
Lundblad, Marie W. |
title |
Reference Values for DXA-Derived Visceral Adipose Tissue in Adults 40 Years and Older from a European Population: The Tromsø Study 2015–2016 |
title_short |
Reference Values for DXA-Derived Visceral Adipose Tissue in Adults 40 Years and Older from a European Population: The Tromsø Study 2015–2016 |
title_full |
Reference Values for DXA-Derived Visceral Adipose Tissue in Adults 40 Years and Older from a European Population: The Tromsø Study 2015–2016 |
title_fullStr |
Reference Values for DXA-Derived Visceral Adipose Tissue in Adults 40 Years and Older from a European Population: The Tromsø Study 2015–2016 |
title_full_unstemmed |
Reference Values for DXA-Derived Visceral Adipose Tissue in Adults 40 Years and Older from a European Population: The Tromsø Study 2015–2016 |
title_sort |
reference values for dxa-derived visceral adipose tissue in adults 40 years and older from a european population: the tromsø study 2015–2016 |
publisher |
Hindawi |
publishDate |
2021 |
url |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8147540/ https://doi.org/10.1155/2021/6634536 |
geographic |
Tromsø |
geographic_facet |
Tromsø |
genre |
Tromsø |
genre_facet |
Tromsø |
op_source |
J Obes |
op_relation |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8147540/ http://dx.doi.org/10.1155/2021/6634536 |
op_rights |
Copyright © 2021 Marie W. Lundblad et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
op_rightsnorm |
CC-BY |
op_doi |
https://doi.org/10.1155/2021/6634536 |
container_title |
Journal of Obesity |
container_volume |
2021 |
container_start_page |
1 |
op_container_end_page |
10 |
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1766219242161569792 |