Declined expressing mRNA of beta-defensin 108 from epididymis is associated with decreased sperm motility in blue fox (Vulpes lagopus)

BACKGROUND: Fecundity is important for farm blue fox (Vulpes lagopus), who with asthenospermia have be a problem in some of farms in China. A key symptom of asthenospermia is decreased sperm motility. The decreased secreting beta-defensin108 (vBD108) of blue fox is speculated be related to asthenosp...

Full description

Bibliographic Details
Published in:BMC Veterinary Research
Main Authors: Wu, Ping, Liu, Tao-lin, Li, Ling-ling, Liu, Zhi-ping, Tian, Li-hong, Hou, Zhi-jun
Format: Text
Language:English
Published: BioMed Central 2021
Subjects:
Research Article
Vulpes lagopus
Online Access:http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7789387/
https://doi.org/10.1186/s12917-020-02697-6
id ftpubmed:oai:pubmedcentral.nih.gov:7789387
record_format openpolar
spelling ftpubmed:oai:pubmedcentral.nih.gov:7789387 2023-05-15T18:42:58+02:00 Declined expressing mRNA of beta-defensin 108 from epididymis is associated with decreased sperm motility in blue fox (Vulpes lagopus) Wu, Ping Liu, Tao-lin Li, Ling-ling Liu, Zhi-ping Tian, Li-hong Hou, Zhi-jun 2021-01-07 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7789387/ https://doi.org/10.1186/s12917-020-02697-6 en eng BioMed Central http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7789387/ http://dx.doi.org/10.1186/s12917-020-02697-6 © The Author(s) 2020 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data. CC0 PDM CC-BY BMC Vet Res Research Article Text 2021 ftpubmed https://doi.org/10.1186/s12917-020-02697-6 2021-01-10T01:45:21Z BACKGROUND: Fecundity is important for farm blue fox (Vulpes lagopus), who with asthenospermia have be a problem in some of farms in China. A key symptom of asthenospermia is decreased sperm motility. The decreased secreting beta-defensin108 (vBD108) of blue fox is speculated be related to asthenospermia. To clarify this idea, the mRNA expression of vBD108 in testis and epididymis of blue foxes with asthenospermia were detected and compared to the healthy one. The antibody was prepared and analyzed by immunohistochemistry. RESULTS: The vBD108 in testis and epididymis was found both in blue fox with asthenospermia and healthy group by the method of immunohistochemistry. The expression of vBD108 mRNA in testes (P < 0.05) and epididymal corpus (P < 0.0001) in asthenospermia group was lower than that in healthy group. CONCLUSIONS: These results suggested that vBD108 deficiency may related to blue fox asthenospermia. Meanwhile, the study on the blue fox vBD108 provides a hopeful direction to explore the pathogenesis of blue fox asthenospermia in the future. Text Vulpes lagopus PubMed Central (PMC) BMC Veterinary Research 17 1
institution Open Polar
collection PubMed Central (PMC)
op_collection_id ftpubmed
language English
topic Research Article
spellingShingle Research Article
Wu, Ping
Liu, Tao-lin
Li, Ling-ling
Liu, Zhi-ping
Tian, Li-hong
Hou, Zhi-jun
Declined expressing mRNA of beta-defensin 108 from epididymis is associated with decreased sperm motility in blue fox (Vulpes lagopus)
topic_facet Research Article
description BACKGROUND: Fecundity is important for farm blue fox (Vulpes lagopus), who with asthenospermia have be a problem in some of farms in China. A key symptom of asthenospermia is decreased sperm motility. The decreased secreting beta-defensin108 (vBD108) of blue fox is speculated be related to asthenospermia. To clarify this idea, the mRNA expression of vBD108 in testis and epididymis of blue foxes with asthenospermia were detected and compared to the healthy one. The antibody was prepared and analyzed by immunohistochemistry. RESULTS: The vBD108 in testis and epididymis was found both in blue fox with asthenospermia and healthy group by the method of immunohistochemistry. The expression of vBD108 mRNA in testes (P < 0.05) and epididymal corpus (P < 0.0001) in asthenospermia group was lower than that in healthy group. CONCLUSIONS: These results suggested that vBD108 deficiency may related to blue fox asthenospermia. Meanwhile, the study on the blue fox vBD108 provides a hopeful direction to explore the pathogenesis of blue fox asthenospermia in the future.
format Text
author Wu, Ping
Liu, Tao-lin
Li, Ling-ling
Liu, Zhi-ping
Tian, Li-hong
Hou, Zhi-jun
author_facet Wu, Ping
Liu, Tao-lin
Li, Ling-ling
Liu, Zhi-ping
Tian, Li-hong
Hou, Zhi-jun
author_sort Wu, Ping
title Declined expressing mRNA of beta-defensin 108 from epididymis is associated with decreased sperm motility in blue fox (Vulpes lagopus)
title_short Declined expressing mRNA of beta-defensin 108 from epididymis is associated with decreased sperm motility in blue fox (Vulpes lagopus)
title_full Declined expressing mRNA of beta-defensin 108 from epididymis is associated with decreased sperm motility in blue fox (Vulpes lagopus)
title_fullStr Declined expressing mRNA of beta-defensin 108 from epididymis is associated with decreased sperm motility in blue fox (Vulpes lagopus)
title_full_unstemmed Declined expressing mRNA of beta-defensin 108 from epididymis is associated with decreased sperm motility in blue fox (Vulpes lagopus)
title_sort declined expressing mrna of beta-defensin 108 from epididymis is associated with decreased sperm motility in blue fox (vulpes lagopus)
publisher BioMed Central
publishDate 2021
url http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7789387/
https://doi.org/10.1186/s12917-020-02697-6
genre Vulpes lagopus
genre_facet Vulpes lagopus
op_source BMC Vet Res
op_relation http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7789387/
http://dx.doi.org/10.1186/s12917-020-02697-6
op_rights © The Author(s) 2020
Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
op_rightsnorm CC0
PDM
CC-BY
op_doi https://doi.org/10.1186/s12917-020-02697-6
container_title BMC Veterinary Research
container_volume 17
container_issue 1
_version_ 1766232735128485888

Similar Items