Useful island block geometries of a passive intensity modulator used for intensity‐modulated bolus electron conformal therapy

PURPOSE: This project determined the range of island block geometric configurations useful for the clinical utilization of intensity‐modulated bolus electron conformal therapy (IM‐BECT). METHODS: Multiple half‐beam island block geometries were studied for seven electron energies 7‐20 MeV at 100 and...

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Published in:Journal of Applied Clinical Medical Physics
Main Authors: Chambers, Erin L., Carver, Robert L., Hogstrom, Kenneth R.
Format: Text
Language:English
Published: John Wiley and Sons Inc. 2020
Subjects:
Online Access:http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7769403/
http://www.ncbi.nlm.nih.gov/pubmed/33207033
https://doi.org/10.1002/acm2.13079
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spelling ftpubmed:oai:pubmedcentral.nih.gov:7769403 2023-05-15T18:42:27+02:00 Useful island block geometries of a passive intensity modulator used for intensity‐modulated bolus electron conformal therapy Chambers, Erin L. Carver, Robert L. Hogstrom, Kenneth R. 2020-11-18 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7769403/ http://www.ncbi.nlm.nih.gov/pubmed/33207033 https://doi.org/10.1002/acm2.13079 en eng John Wiley and Sons Inc. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7769403/ http://www.ncbi.nlm.nih.gov/pubmed/33207033 http://dx.doi.org/10.1002/acm2.13079 © 2020 The Authors. Journal of Applied Clinical Medical Physics published by Wiley Periodicals LLC on behalf of American Association of Physicists in Medicine This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. CC-BY J Appl Clin Med Phys Radiation Oncology Physics Text 2020 ftpubmed https://doi.org/10.1002/acm2.13079 2021-01-03T02:00:05Z PURPOSE: This project determined the range of island block geometric configurations useful for the clinical utilization of intensity‐modulated bolus electron conformal therapy (IM‐BECT). METHODS: Multiple half‐beam island block geometries were studied for seven electron energies 7‐20 MeV at 100 and 103 cm source‐to‐surface distance (SSD). We studied relative fluence distributions at 0.5 cm and 2.0 cm depths in water, resulting in 28 unique beam conditions. For each beam condition, we studied intensity reduction factor (IRF) values of 0.70, 0.75, 0.80, 0.85, 0.90, and 0.95, and hexagonal packing separations for the island blocks of 0.50, 0.75, 1.00, 1.25, and 1.50 cm, that is, 30 unique IM configurations and 840 unique beam‐IM combinations. A combination was deemed acceptable if the average intensity downstream of the intensity modulator agreed within 2% of that intended and the variation in fluence was less than ±2%. RESULTS: For 100 cm SSD, and for 0.5 cm depth, results showed that beam energies above 13 MeV did not exhibit sufficient scatter to produce clinically acceptable fluence (intensity) distributions for all IRF values (0.70–0.95). In particular, 20 MeV fluence distributions were unacceptable for any values, and acceptable 16 MeV fluence distributions were limited to a minimum IRF of 0.85. For the 2.0 cm depth, beam energies up to and including 20 MeV had acceptable fluence distributions. For 103 cm SSD and for 0.5 cm and 2.0 cm depths, results showed that all beam energies (7–20 MeV) had clinically acceptable fluence distributions for all IRF values (0.70–0.95). In general, the more clinically likely 103 cm SSD had acceptable fluence distributions with larger separations (r), which allow larger block diameters. CONCLUSION: The geometric operating range of island block separations and IRF values (block diameters) producing clinically appropriate IM electron beams has been determined. Text Useful Island PubMed Central (PMC) Useful Island ENVELOPE(-62.871,-62.871,-64.717,-64.717) Journal of Applied Clinical Medical Physics 21 12 131 145
institution Open Polar
collection PubMed Central (PMC)
op_collection_id ftpubmed
language English
topic Radiation Oncology Physics
spellingShingle Radiation Oncology Physics
Chambers, Erin L.
Carver, Robert L.
Hogstrom, Kenneth R.
Useful island block geometries of a passive intensity modulator used for intensity‐modulated bolus electron conformal therapy
topic_facet Radiation Oncology Physics
description PURPOSE: This project determined the range of island block geometric configurations useful for the clinical utilization of intensity‐modulated bolus electron conformal therapy (IM‐BECT). METHODS: Multiple half‐beam island block geometries were studied for seven electron energies 7‐20 MeV at 100 and 103 cm source‐to‐surface distance (SSD). We studied relative fluence distributions at 0.5 cm and 2.0 cm depths in water, resulting in 28 unique beam conditions. For each beam condition, we studied intensity reduction factor (IRF) values of 0.70, 0.75, 0.80, 0.85, 0.90, and 0.95, and hexagonal packing separations for the island blocks of 0.50, 0.75, 1.00, 1.25, and 1.50 cm, that is, 30 unique IM configurations and 840 unique beam‐IM combinations. A combination was deemed acceptable if the average intensity downstream of the intensity modulator agreed within 2% of that intended and the variation in fluence was less than ±2%. RESULTS: For 100 cm SSD, and for 0.5 cm depth, results showed that beam energies above 13 MeV did not exhibit sufficient scatter to produce clinically acceptable fluence (intensity) distributions for all IRF values (0.70–0.95). In particular, 20 MeV fluence distributions were unacceptable for any values, and acceptable 16 MeV fluence distributions were limited to a minimum IRF of 0.85. For the 2.0 cm depth, beam energies up to and including 20 MeV had acceptable fluence distributions. For 103 cm SSD and for 0.5 cm and 2.0 cm depths, results showed that all beam energies (7–20 MeV) had clinically acceptable fluence distributions for all IRF values (0.70–0.95). In general, the more clinically likely 103 cm SSD had acceptable fluence distributions with larger separations (r), which allow larger block diameters. CONCLUSION: The geometric operating range of island block separations and IRF values (block diameters) producing clinically appropriate IM electron beams has been determined.
format Text
author Chambers, Erin L.
Carver, Robert L.
Hogstrom, Kenneth R.
author_facet Chambers, Erin L.
Carver, Robert L.
Hogstrom, Kenneth R.
author_sort Chambers, Erin L.
title Useful island block geometries of a passive intensity modulator used for intensity‐modulated bolus electron conformal therapy
title_short Useful island block geometries of a passive intensity modulator used for intensity‐modulated bolus electron conformal therapy
title_full Useful island block geometries of a passive intensity modulator used for intensity‐modulated bolus electron conformal therapy
title_fullStr Useful island block geometries of a passive intensity modulator used for intensity‐modulated bolus electron conformal therapy
title_full_unstemmed Useful island block geometries of a passive intensity modulator used for intensity‐modulated bolus electron conformal therapy
title_sort useful island block geometries of a passive intensity modulator used for intensity‐modulated bolus electron conformal therapy
publisher John Wiley and Sons Inc.
publishDate 2020
url http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7769403/
http://www.ncbi.nlm.nih.gov/pubmed/33207033
https://doi.org/10.1002/acm2.13079
long_lat ENVELOPE(-62.871,-62.871,-64.717,-64.717)
geographic Useful Island
geographic_facet Useful Island
genre Useful Island
genre_facet Useful Island
op_source J Appl Clin Med Phys
op_relation http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7769403/
http://www.ncbi.nlm.nih.gov/pubmed/33207033
http://dx.doi.org/10.1002/acm2.13079
op_rights © 2020 The Authors. Journal of Applied Clinical Medical Physics published by Wiley Periodicals LLC on behalf of American Association of Physicists in Medicine
This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
op_rightsnorm CC-BY
op_doi https://doi.org/10.1002/acm2.13079
container_title Journal of Applied Clinical Medical Physics
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container_issue 12
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