A new approach to estimating the prevalence of hereditary hearing loss: An analysis of the distribution of sign language users based on census data in Russia
The absence of comparable epidemiological data challenges the correct estimation of the prevalence of congenital hearing loss (HL) around the world. Sign language (SL) is known as the main type of communication of deaf people. We suggest that the distribution of SL can be interpreted as an indirect...
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ftpubmed:oai:pubmedcentral.nih.gov:7703874 2023-05-15T18:44:31+02:00 A new approach to estimating the prevalence of hereditary hearing loss: An analysis of the distribution of sign language users based on census data in Russia Romanov, Georgii P. Pshennikova, Vera G. Lashin, Sergey A. Solovyev, Aisen V. Teryutin, Fedor M. Cherdonova, Aleksandra M. Borisova, Tuyara V. Sazonov, Nikolay N. Khusnutdinova, Elza K. Posukh, Olga L. Fedorova, Sardana A. Barashkov, Nikolay A. 2020-11-30 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7703874/ http://www.ncbi.nlm.nih.gov/pubmed/33253245 https://doi.org/10.1371/journal.pone.0242219 en eng Public Library of Science http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7703874/ http://www.ncbi.nlm.nih.gov/pubmed/33253245 http://dx.doi.org/10.1371/journal.pone.0242219 © 2020 Romanov et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. CC-BY PLoS One Research Article Text 2020 ftpubmed https://doi.org/10.1371/journal.pone.0242219 2020-12-06T02:06:19Z The absence of comparable epidemiological data challenges the correct estimation of the prevalence of congenital hearing loss (HL) around the world. Sign language (SL) is known as the main type of communication of deaf people. We suggest that the distribution of SL can be interpreted as an indirect indicator of the prevalence of congenital HL. Since a significant part of congenital HL is due to genetic causes, an assessment of the distribution of SL users can reveal regions with an extensive accumulation of hereditary HL. For the first time, we analyzed the data on the distribution of SL users that became available for the total population of Russia by the 2010 census. Seventy-three out of 85 federal regions of Russia were ranked into three groups by the 25(th) and 75(th) percentiles of the proportion of SL users: 14 regions—“low proportion”; 48 regions—“average proportion”; and 11 regions—“high proportion”. We consider that the observed uneven prevalence of SL users can reflect underlying hereditary forms of congenital HL accumulated in certain populations by specific genetic background and population structure. At least, the data from this study indicate that the highest proportions of SL users detected in some Siberian regions are consistent with the reported accumulation of specific hereditary HL forms in indigenous Yakut, Tuvinian and Altaian populations. Text Yakut PubMed Central (PMC) PLOS ONE 15 11 e0242219 |
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Research Article Romanov, Georgii P. Pshennikova, Vera G. Lashin, Sergey A. Solovyev, Aisen V. Teryutin, Fedor M. Cherdonova, Aleksandra M. Borisova, Tuyara V. Sazonov, Nikolay N. Khusnutdinova, Elza K. Posukh, Olga L. Fedorova, Sardana A. Barashkov, Nikolay A. A new approach to estimating the prevalence of hereditary hearing loss: An analysis of the distribution of sign language users based on census data in Russia |
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Research Article |
description |
The absence of comparable epidemiological data challenges the correct estimation of the prevalence of congenital hearing loss (HL) around the world. Sign language (SL) is known as the main type of communication of deaf people. We suggest that the distribution of SL can be interpreted as an indirect indicator of the prevalence of congenital HL. Since a significant part of congenital HL is due to genetic causes, an assessment of the distribution of SL users can reveal regions with an extensive accumulation of hereditary HL. For the first time, we analyzed the data on the distribution of SL users that became available for the total population of Russia by the 2010 census. Seventy-three out of 85 federal regions of Russia were ranked into three groups by the 25(th) and 75(th) percentiles of the proportion of SL users: 14 regions—“low proportion”; 48 regions—“average proportion”; and 11 regions—“high proportion”. We consider that the observed uneven prevalence of SL users can reflect underlying hereditary forms of congenital HL accumulated in certain populations by specific genetic background and population structure. At least, the data from this study indicate that the highest proportions of SL users detected in some Siberian regions are consistent with the reported accumulation of specific hereditary HL forms in indigenous Yakut, Tuvinian and Altaian populations. |
format |
Text |
author |
Romanov, Georgii P. Pshennikova, Vera G. Lashin, Sergey A. Solovyev, Aisen V. Teryutin, Fedor M. Cherdonova, Aleksandra M. Borisova, Tuyara V. Sazonov, Nikolay N. Khusnutdinova, Elza K. Posukh, Olga L. Fedorova, Sardana A. Barashkov, Nikolay A. |
author_facet |
Romanov, Georgii P. Pshennikova, Vera G. Lashin, Sergey A. Solovyev, Aisen V. Teryutin, Fedor M. Cherdonova, Aleksandra M. Borisova, Tuyara V. Sazonov, Nikolay N. Khusnutdinova, Elza K. Posukh, Olga L. Fedorova, Sardana A. Barashkov, Nikolay A. |
author_sort |
Romanov, Georgii P. |
title |
A new approach to estimating the prevalence of hereditary hearing loss: An analysis of the distribution of sign language users based on census data in Russia |
title_short |
A new approach to estimating the prevalence of hereditary hearing loss: An analysis of the distribution of sign language users based on census data in Russia |
title_full |
A new approach to estimating the prevalence of hereditary hearing loss: An analysis of the distribution of sign language users based on census data in Russia |
title_fullStr |
A new approach to estimating the prevalence of hereditary hearing loss: An analysis of the distribution of sign language users based on census data in Russia |
title_full_unstemmed |
A new approach to estimating the prevalence of hereditary hearing loss: An analysis of the distribution of sign language users based on census data in Russia |
title_sort |
new approach to estimating the prevalence of hereditary hearing loss: an analysis of the distribution of sign language users based on census data in russia |
publisher |
Public Library of Science |
publishDate |
2020 |
url |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7703874/ http://www.ncbi.nlm.nih.gov/pubmed/33253245 https://doi.org/10.1371/journal.pone.0242219 |
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Yakut |
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Yakut |
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PLoS One |
op_relation |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7703874/ http://www.ncbi.nlm.nih.gov/pubmed/33253245 http://dx.doi.org/10.1371/journal.pone.0242219 |
op_rights |
© 2020 Romanov et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
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https://doi.org/10.1371/journal.pone.0242219 |
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PLOS ONE |
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15 |
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11 |
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