Artificial whole genome duplication in paleopolyploid sturgeons yields highest documented chromosome number in vertebrates
Critically endangered sturgeons, having undergone three whole genome duplication events, represent an exceptional example of ploidy plasticity in vertebrates. Three extant ploidy groups, combined with autopolyploidization, interspecific hybridization and the fertility of hybrids are important issues...
Published in: | Scientific Reports |
---|---|
Main Authors: | , , , |
Format: | Text |
Language: | English |
Published: |
Nature Publishing Group UK
2020
|
Subjects: | |
Online Access: | http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7665173/ http://www.ncbi.nlm.nih.gov/pubmed/33184410 https://doi.org/10.1038/s41598-020-76680-4 |
id |
ftpubmed:oai:pubmedcentral.nih.gov:7665173 |
---|---|
record_format |
openpolar |
spelling |
ftpubmed:oai:pubmedcentral.nih.gov:7665173 2023-05-15T13:01:49+02:00 Artificial whole genome duplication in paleopolyploid sturgeons yields highest documented chromosome number in vertebrates Lebeda, Ievgen Ráb, Petr Majtánová, Zuzana Flajšhans, Martin 2020-11-12 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7665173/ http://www.ncbi.nlm.nih.gov/pubmed/33184410 https://doi.org/10.1038/s41598-020-76680-4 en eng Nature Publishing Group UK http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7665173/ http://www.ncbi.nlm.nih.gov/pubmed/33184410 http://dx.doi.org/10.1038/s41598-020-76680-4 © The Author(s) 2020 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. CC-BY Sci Rep Article Text 2020 ftpubmed https://doi.org/10.1038/s41598-020-76680-4 2020-11-22T01:35:27Z Critically endangered sturgeons, having undergone three whole genome duplication events, represent an exceptional example of ploidy plasticity in vertebrates. Three extant ploidy groups, combined with autopolyploidization, interspecific hybridization and the fertility of hybrids are important issues in sturgeon conservation and aquaculture. Here we demonstrate that the sturgeon genome can undergo numerous alterations of ploidy without severe physiological consequences, producing progeny with a range of ploidy levels and extremely high chromosome numbers. Artificial suppression of the first mitotic division alone, or in combination with suppression of the second meiotic division of functionally tetraploid zygotes (4n, C-value = 4.15) of Siberian sturgeon Acipenser baerii and Russian sturgeon A. gueldenstaedtii resulted in progeny of various ploidy levels—diploid/hexaploid (2n/6n) mosaics, hexaploid, octoploid juveniles (8n), and dodecaploid (12n) larvae. Counts between 477 to 520 chromosomes in octoploid juveniles of both sturgeons confirmed the modal chromosome numbers of parental species had been doubled. This exceeds the highest previously documented chromosome count among vertebrates 2n ~ 446 in the cyprinid fish Ptychobarbus dipogon. Text Acipenser baerii Siberian sturgeon PubMed Central (PMC) Scientific Reports 10 1 |
institution |
Open Polar |
collection |
PubMed Central (PMC) |
op_collection_id |
ftpubmed |
language |
English |
topic |
Article |
spellingShingle |
Article Lebeda, Ievgen Ráb, Petr Majtánová, Zuzana Flajšhans, Martin Artificial whole genome duplication in paleopolyploid sturgeons yields highest documented chromosome number in vertebrates |
topic_facet |
Article |
description |
Critically endangered sturgeons, having undergone three whole genome duplication events, represent an exceptional example of ploidy plasticity in vertebrates. Three extant ploidy groups, combined with autopolyploidization, interspecific hybridization and the fertility of hybrids are important issues in sturgeon conservation and aquaculture. Here we demonstrate that the sturgeon genome can undergo numerous alterations of ploidy without severe physiological consequences, producing progeny with a range of ploidy levels and extremely high chromosome numbers. Artificial suppression of the first mitotic division alone, or in combination with suppression of the second meiotic division of functionally tetraploid zygotes (4n, C-value = 4.15) of Siberian sturgeon Acipenser baerii and Russian sturgeon A. gueldenstaedtii resulted in progeny of various ploidy levels—diploid/hexaploid (2n/6n) mosaics, hexaploid, octoploid juveniles (8n), and dodecaploid (12n) larvae. Counts between 477 to 520 chromosomes in octoploid juveniles of both sturgeons confirmed the modal chromosome numbers of parental species had been doubled. This exceeds the highest previously documented chromosome count among vertebrates 2n ~ 446 in the cyprinid fish Ptychobarbus dipogon. |
format |
Text |
author |
Lebeda, Ievgen Ráb, Petr Majtánová, Zuzana Flajšhans, Martin |
author_facet |
Lebeda, Ievgen Ráb, Petr Majtánová, Zuzana Flajšhans, Martin |
author_sort |
Lebeda, Ievgen |
title |
Artificial whole genome duplication in paleopolyploid sturgeons yields highest documented chromosome number in vertebrates |
title_short |
Artificial whole genome duplication in paleopolyploid sturgeons yields highest documented chromosome number in vertebrates |
title_full |
Artificial whole genome duplication in paleopolyploid sturgeons yields highest documented chromosome number in vertebrates |
title_fullStr |
Artificial whole genome duplication in paleopolyploid sturgeons yields highest documented chromosome number in vertebrates |
title_full_unstemmed |
Artificial whole genome duplication in paleopolyploid sturgeons yields highest documented chromosome number in vertebrates |
title_sort |
artificial whole genome duplication in paleopolyploid sturgeons yields highest documented chromosome number in vertebrates |
publisher |
Nature Publishing Group UK |
publishDate |
2020 |
url |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7665173/ http://www.ncbi.nlm.nih.gov/pubmed/33184410 https://doi.org/10.1038/s41598-020-76680-4 |
genre |
Acipenser baerii Siberian sturgeon |
genre_facet |
Acipenser baerii Siberian sturgeon |
op_source |
Sci Rep |
op_relation |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7665173/ http://www.ncbi.nlm.nih.gov/pubmed/33184410 http://dx.doi.org/10.1038/s41598-020-76680-4 |
op_rights |
© The Author(s) 2020 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. |
op_rightsnorm |
CC-BY |
op_doi |
https://doi.org/10.1038/s41598-020-76680-4 |
container_title |
Scientific Reports |
container_volume |
10 |
container_issue |
1 |
_version_ |
1766287528289107968 |