Differential immune gene expression associated with contemporary range expansion in two invasive rodents in Senegal
Biological invasions are major anthropogenic changes associated with threats to biodiversity and health. However, what determines the successful establishment and spread of introduced populations remains unclear. Here, we explore several hypotheses linking invasion success and immune phenotype trait...
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ftpubmed:oai:pubmedcentral.nih.gov:7589499 2023-05-15T18:05:26+02:00 Differential immune gene expression associated with contemporary range expansion in two invasive rodents in Senegal Charbonnel, Nathalie Galan, Maxime Tatard, Caroline Loiseau, Anne Diagne, Christophe Dalecky, Ambroise Parrinello, Hugues Rialle, Stephanie Severac, Dany Brouat, Carine 2020-10-26 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7589499/ http://www.ncbi.nlm.nih.gov/pubmed/33106535 https://doi.org/10.1038/s41598-020-75060-2 en eng Nature Publishing Group UK http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7589499/ http://www.ncbi.nlm.nih.gov/pubmed/33106535 http://dx.doi.org/10.1038/s41598-020-75060-2 © The Author(s) 2020 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. CC-BY Sci Rep Article Text 2020 ftpubmed https://doi.org/10.1038/s41598-020-75060-2 2020-11-01T02:00:00Z Biological invasions are major anthropogenic changes associated with threats to biodiversity and health. However, what determines the successful establishment and spread of introduced populations remains unclear. Here, we explore several hypotheses linking invasion success and immune phenotype traits, including those based on the evolution of increased competitive ability concept. We compared gene expression profiles between anciently and recently established populations of two major invading species, the house mouse Mus musculus domesticus and the black rat Rattus rattus, in Senegal (West Africa). Transcriptome analyses identified differential expression between anciently and recently established populations for 364 mouse genes and 83 rat genes. All immune-related genes displaying differential expression along the mouse invasion route were overexpressed at three of the four recently invaded sites studied. Complement activation pathway genes were overrepresented among these genes. By contrast, no particular immunological process was found to be overrepresented among the differentially expressed genes of black rat. Changes in transcriptome profiles were thus observed along invasion routes, but with different specific patterns between the two invasive species. These changes may be driven by increases in infection risks at sites recently invaded by the house mouse, and by stochastic events associated with colonization history for the black rat. These results constitute a first step toward the identification of immune eco-evolutionary processes potentially involved in the invasion success of these two rodent species. Text Rattus rattus PubMed Central (PMC) Scientific Reports 10 1 |
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Article Charbonnel, Nathalie Galan, Maxime Tatard, Caroline Loiseau, Anne Diagne, Christophe Dalecky, Ambroise Parrinello, Hugues Rialle, Stephanie Severac, Dany Brouat, Carine Differential immune gene expression associated with contemporary range expansion in two invasive rodents in Senegal |
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Biological invasions are major anthropogenic changes associated with threats to biodiversity and health. However, what determines the successful establishment and spread of introduced populations remains unclear. Here, we explore several hypotheses linking invasion success and immune phenotype traits, including those based on the evolution of increased competitive ability concept. We compared gene expression profiles between anciently and recently established populations of two major invading species, the house mouse Mus musculus domesticus and the black rat Rattus rattus, in Senegal (West Africa). Transcriptome analyses identified differential expression between anciently and recently established populations for 364 mouse genes and 83 rat genes. All immune-related genes displaying differential expression along the mouse invasion route were overexpressed at three of the four recently invaded sites studied. Complement activation pathway genes were overrepresented among these genes. By contrast, no particular immunological process was found to be overrepresented among the differentially expressed genes of black rat. Changes in transcriptome profiles were thus observed along invasion routes, but with different specific patterns between the two invasive species. These changes may be driven by increases in infection risks at sites recently invaded by the house mouse, and by stochastic events associated with colonization history for the black rat. These results constitute a first step toward the identification of immune eco-evolutionary processes potentially involved in the invasion success of these two rodent species. |
format |
Text |
author |
Charbonnel, Nathalie Galan, Maxime Tatard, Caroline Loiseau, Anne Diagne, Christophe Dalecky, Ambroise Parrinello, Hugues Rialle, Stephanie Severac, Dany Brouat, Carine |
author_facet |
Charbonnel, Nathalie Galan, Maxime Tatard, Caroline Loiseau, Anne Diagne, Christophe Dalecky, Ambroise Parrinello, Hugues Rialle, Stephanie Severac, Dany Brouat, Carine |
author_sort |
Charbonnel, Nathalie |
title |
Differential immune gene expression associated with contemporary range expansion in two invasive rodents in Senegal |
title_short |
Differential immune gene expression associated with contemporary range expansion in two invasive rodents in Senegal |
title_full |
Differential immune gene expression associated with contemporary range expansion in two invasive rodents in Senegal |
title_fullStr |
Differential immune gene expression associated with contemporary range expansion in two invasive rodents in Senegal |
title_full_unstemmed |
Differential immune gene expression associated with contemporary range expansion in two invasive rodents in Senegal |
title_sort |
differential immune gene expression associated with contemporary range expansion in two invasive rodents in senegal |
publisher |
Nature Publishing Group UK |
publishDate |
2020 |
url |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7589499/ http://www.ncbi.nlm.nih.gov/pubmed/33106535 https://doi.org/10.1038/s41598-020-75060-2 |
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Rattus rattus |
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Rattus rattus |
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Sci Rep |
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7589499/ http://www.ncbi.nlm.nih.gov/pubmed/33106535 http://dx.doi.org/10.1038/s41598-020-75060-2 |
op_rights |
© The Author(s) 2020 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. |
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CC-BY |
op_doi |
https://doi.org/10.1038/s41598-020-75060-2 |
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Scientific Reports |
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