In situ breast cancer incidence patterns in Iceland and differences in ductal carcinoma in situ treatment compared to Sweden
The purpose was to review the incidence of in situ carcinoma in Iceland after initiating population-based mammography screening in 1987 and to compare management of ductal carcinoma in situ (DCIS) between Iceland and the Uppsala–Örebro region (UÖR) in Central Sweden. The Icelandic Cancer Registry pr...
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ftpubmed:oai:pubmedcentral.nih.gov:7572374 2023-05-15T16:42:21+02:00 In situ breast cancer incidence patterns in Iceland and differences in ductal carcinoma in situ treatment compared to Sweden Agustsson, Arnar S. Birgisson, Helgi Agnarsson, Bjarni A. Jonsson, Thorvaldur Stefansdottir, Hrefna Wärnberg, Fredrik Lambe, Mats Tryggvadottir, Laufey Sverrisdottir, Asgerdur 2020-10-19 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7572374/ http://www.ncbi.nlm.nih.gov/pubmed/33077767 https://doi.org/10.1038/s41598-020-74134-5 en eng Nature Publishing Group UK http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7572374/ http://www.ncbi.nlm.nih.gov/pubmed/33077767 http://dx.doi.org/10.1038/s41598-020-74134-5 © The Author(s) 2020 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. CC-BY Sci Rep Article Text 2020 ftpubmed https://doi.org/10.1038/s41598-020-74134-5 2020-10-25T00:51:02Z The purpose was to review the incidence of in situ carcinoma in Iceland after initiating population-based mammography screening in 1987 and to compare management of ductal carcinoma in situ (DCIS) between Iceland and the Uppsala–Örebro region (UÖR) in Central Sweden. The Icelandic Cancer Registry provided data on in situ breast carcinomas for women between 1957 and 2017. Clinical data for women with DCIS between 2008 and 2014 was extracted from hospital records and compared to women diagnosed in UÖR. In Iceland, in situ carcinoma incidence increased from 7 to 30 per 100 000 women per year, following the introduction of organised mammography screening. The proportion of in situ carcinoma of all breast carcinomas increased from 4 to 12%. More than one third (35%) of women diagnosed with DCIS in Iceland were older than 70 years versus 18% in UÖR. In Iceland, 49% of all DCIS women underwent mastectomy compared to 40% in UÖR. The incidence of in situ carcinoma in Iceland increased four-fold after the uptake of population-based mammography screening causing considerable risk of overtreatment. Differences in treatment of DCIS were seen between Iceland and UÖR, revealing the importance of quality registration for monitoring patterns of management. Text Iceland PubMed Central (PMC) Scientific Reports 10 1 |
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Article Agustsson, Arnar S. Birgisson, Helgi Agnarsson, Bjarni A. Jonsson, Thorvaldur Stefansdottir, Hrefna Wärnberg, Fredrik Lambe, Mats Tryggvadottir, Laufey Sverrisdottir, Asgerdur In situ breast cancer incidence patterns in Iceland and differences in ductal carcinoma in situ treatment compared to Sweden |
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The purpose was to review the incidence of in situ carcinoma in Iceland after initiating population-based mammography screening in 1987 and to compare management of ductal carcinoma in situ (DCIS) between Iceland and the Uppsala–Örebro region (UÖR) in Central Sweden. The Icelandic Cancer Registry provided data on in situ breast carcinomas for women between 1957 and 2017. Clinical data for women with DCIS between 2008 and 2014 was extracted from hospital records and compared to women diagnosed in UÖR. In Iceland, in situ carcinoma incidence increased from 7 to 30 per 100 000 women per year, following the introduction of organised mammography screening. The proportion of in situ carcinoma of all breast carcinomas increased from 4 to 12%. More than one third (35%) of women diagnosed with DCIS in Iceland were older than 70 years versus 18% in UÖR. In Iceland, 49% of all DCIS women underwent mastectomy compared to 40% in UÖR. The incidence of in situ carcinoma in Iceland increased four-fold after the uptake of population-based mammography screening causing considerable risk of overtreatment. Differences in treatment of DCIS were seen between Iceland and UÖR, revealing the importance of quality registration for monitoring patterns of management. |
format |
Text |
author |
Agustsson, Arnar S. Birgisson, Helgi Agnarsson, Bjarni A. Jonsson, Thorvaldur Stefansdottir, Hrefna Wärnberg, Fredrik Lambe, Mats Tryggvadottir, Laufey Sverrisdottir, Asgerdur |
author_facet |
Agustsson, Arnar S. Birgisson, Helgi Agnarsson, Bjarni A. Jonsson, Thorvaldur Stefansdottir, Hrefna Wärnberg, Fredrik Lambe, Mats Tryggvadottir, Laufey Sverrisdottir, Asgerdur |
author_sort |
Agustsson, Arnar S. |
title |
In situ breast cancer incidence patterns in Iceland and differences in ductal carcinoma in situ treatment compared to Sweden |
title_short |
In situ breast cancer incidence patterns in Iceland and differences in ductal carcinoma in situ treatment compared to Sweden |
title_full |
In situ breast cancer incidence patterns in Iceland and differences in ductal carcinoma in situ treatment compared to Sweden |
title_fullStr |
In situ breast cancer incidence patterns in Iceland and differences in ductal carcinoma in situ treatment compared to Sweden |
title_full_unstemmed |
In situ breast cancer incidence patterns in Iceland and differences in ductal carcinoma in situ treatment compared to Sweden |
title_sort |
in situ breast cancer incidence patterns in iceland and differences in ductal carcinoma in situ treatment compared to sweden |
publisher |
Nature Publishing Group UK |
publishDate |
2020 |
url |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7572374/ http://www.ncbi.nlm.nih.gov/pubmed/33077767 https://doi.org/10.1038/s41598-020-74134-5 |
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Iceland |
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Iceland |
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Sci Rep |
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7572374/ http://www.ncbi.nlm.nih.gov/pubmed/33077767 http://dx.doi.org/10.1038/s41598-020-74134-5 |
op_rights |
© The Author(s) 2020 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. |
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CC-BY |
op_doi |
https://doi.org/10.1038/s41598-020-74134-5 |
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Scientific Reports |
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