Features and Advantages of Supercritical CO(2) Extraction of Sea Cucumber Cucumaria frondosa japonica Semper, 1868
Extraction process of Cucumaria frondosa japonica Semper, 1868, which are subspecies of Cucumaria frondosa (Gunnerus, 1767), were studied. It was shown that supercritical carbon dioxide extraction of holothuria was more effective than conventional solvent extraction. Step-by-step extraction with car...
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ftpubmed:oai:pubmedcentral.nih.gov:7570654 2023-05-15T15:59:37+02:00 Features and Advantages of Supercritical CO(2) Extraction of Sea Cucumber Cucumaria frondosa japonica Semper, 1868 Zakharenko, Alexander Romanchenko, Denis Thinh, Pham Duc Pikula, Konstantin Hang, Cao Thi Thuy Yuan, Wenpeng Xia, Xuekui Chaika, Vladimir Chernyshev, Valery Zakharenko, Svetlana Razgonova, Mayya Chung, Gyuhwa Golokhvast, Kirill 2020-09-07 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7570654/ http://www.ncbi.nlm.nih.gov/pubmed/32906811 https://doi.org/10.3390/molecules25184088 en eng MDPI http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7570654/ http://www.ncbi.nlm.nih.gov/pubmed/32906811 http://dx.doi.org/10.3390/molecules25184088 © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). CC-BY Molecules Article Text 2020 ftpubmed https://doi.org/10.3390/molecules25184088 2020-11-01T01:36:12Z Extraction process of Cucumaria frondosa japonica Semper, 1868, which are subspecies of Cucumaria frondosa (Gunnerus, 1767), were studied. It was shown that supercritical carbon dioxide extraction of holothuria was more effective than conventional solvent extraction. Step-by-step extraction with carbon dioxide followed by supercritical extraction with the addition of a co-solvent of ethanol can almost double the yields of extracts of triterpene glycosides, styrenes and carotenoids. Moreover, the fraction of triterpene glycosides practically does not contain colored impurities, in contrast to traditional ethanol extraction. The obtained extracts by HPLC in combination with tandem mass spectrometry (HPLC-MS/MS) identified 15 triterpene glycosides, 18 styrene compounds and 14 carotenoids. Supercritical extraction made it possible to obtain extracts with yields superior to conventional hexane and alcohol extracts. Moreover, such an approach with the use of supercritical fluid extraction (SFE) and subsequent profiling of metabolites can help with the study of holothuria species that are not as well studied. Text Cucumaria frondosa PubMed Central (PMC) Molecules 25 18 4088 |
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Article Zakharenko, Alexander Romanchenko, Denis Thinh, Pham Duc Pikula, Konstantin Hang, Cao Thi Thuy Yuan, Wenpeng Xia, Xuekui Chaika, Vladimir Chernyshev, Valery Zakharenko, Svetlana Razgonova, Mayya Chung, Gyuhwa Golokhvast, Kirill Features and Advantages of Supercritical CO(2) Extraction of Sea Cucumber Cucumaria frondosa japonica Semper, 1868 |
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Article |
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Extraction process of Cucumaria frondosa japonica Semper, 1868, which are subspecies of Cucumaria frondosa (Gunnerus, 1767), were studied. It was shown that supercritical carbon dioxide extraction of holothuria was more effective than conventional solvent extraction. Step-by-step extraction with carbon dioxide followed by supercritical extraction with the addition of a co-solvent of ethanol can almost double the yields of extracts of triterpene glycosides, styrenes and carotenoids. Moreover, the fraction of triterpene glycosides practically does not contain colored impurities, in contrast to traditional ethanol extraction. The obtained extracts by HPLC in combination with tandem mass spectrometry (HPLC-MS/MS) identified 15 triterpene glycosides, 18 styrene compounds and 14 carotenoids. Supercritical extraction made it possible to obtain extracts with yields superior to conventional hexane and alcohol extracts. Moreover, such an approach with the use of supercritical fluid extraction (SFE) and subsequent profiling of metabolites can help with the study of holothuria species that are not as well studied. |
format |
Text |
author |
Zakharenko, Alexander Romanchenko, Denis Thinh, Pham Duc Pikula, Konstantin Hang, Cao Thi Thuy Yuan, Wenpeng Xia, Xuekui Chaika, Vladimir Chernyshev, Valery Zakharenko, Svetlana Razgonova, Mayya Chung, Gyuhwa Golokhvast, Kirill |
author_facet |
Zakharenko, Alexander Romanchenko, Denis Thinh, Pham Duc Pikula, Konstantin Hang, Cao Thi Thuy Yuan, Wenpeng Xia, Xuekui Chaika, Vladimir Chernyshev, Valery Zakharenko, Svetlana Razgonova, Mayya Chung, Gyuhwa Golokhvast, Kirill |
author_sort |
Zakharenko, Alexander |
title |
Features and Advantages of Supercritical CO(2) Extraction of Sea Cucumber Cucumaria frondosa japonica Semper, 1868 |
title_short |
Features and Advantages of Supercritical CO(2) Extraction of Sea Cucumber Cucumaria frondosa japonica Semper, 1868 |
title_full |
Features and Advantages of Supercritical CO(2) Extraction of Sea Cucumber Cucumaria frondosa japonica Semper, 1868 |
title_fullStr |
Features and Advantages of Supercritical CO(2) Extraction of Sea Cucumber Cucumaria frondosa japonica Semper, 1868 |
title_full_unstemmed |
Features and Advantages of Supercritical CO(2) Extraction of Sea Cucumber Cucumaria frondosa japonica Semper, 1868 |
title_sort |
features and advantages of supercritical co(2) extraction of sea cucumber cucumaria frondosa japonica semper, 1868 |
publisher |
MDPI |
publishDate |
2020 |
url |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7570654/ http://www.ncbi.nlm.nih.gov/pubmed/32906811 https://doi.org/10.3390/molecules25184088 |
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Cucumaria frondosa |
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Cucumaria frondosa |
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Molecules |
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7570654/ http://www.ncbi.nlm.nih.gov/pubmed/32906811 http://dx.doi.org/10.3390/molecules25184088 |
op_rights |
© 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
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CC-BY |
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https://doi.org/10.3390/molecules25184088 |
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Molecules |
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25 |
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18 |
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4088 |
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1766395545142689792 |