Time trends of vitamin D concentrations in northern Sweden between 1986 and 2014: a population-based cross-sectional study
PURPOSE: Vitamin D, produced through cutaneous photosynthesis or ingested via foods or supplements, has generated considerable research interest due to its potential health effects. However, epidemiological data on the time trends of vitamin D status are sparse, especially from northern Europe. We e...
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ftpubmed:oai:pubmedcentral.nih.gov:7501112 2023-05-15T17:44:18+02:00 Time trends of vitamin D concentrations in northern Sweden between 1986 and 2014: a population-based cross-sectional study Summerhays, Eva Eliasson, Mats Lundqvist, Robert Söderberg, Stefan Zeller, Tanja Oskarsson, Viktor 2019-11-21 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7501112/ http://www.ncbi.nlm.nih.gov/pubmed/31754783 https://doi.org/10.1007/s00394-019-02142-x en eng Springer Berlin Heidelberg http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7501112/ http://www.ncbi.nlm.nih.gov/pubmed/31754783 http://dx.doi.org/10.1007/s00394-019-02142-x © The Author(s) 2019 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. CC-BY Eur J Nutr Original Contribution Text 2019 ftpubmed https://doi.org/10.1007/s00394-019-02142-x 2020-10-04T00:37:02Z PURPOSE: Vitamin D, produced through cutaneous photosynthesis or ingested via foods or supplements, has generated considerable research interest due to its potential health effects. However, epidemiological data on the time trends of vitamin D status are sparse, especially from northern Europe. We examined the time trend of vitamin D concentrations in northern Sweden between 1986 and 2014. METHODS: We used data on 11,129 men and women (aged 25–74 years) from seven population-based surveys (the Northern Sweden MONICA study), recruited between 1986 and 2014. Serum vitamin D (25-hydroxyvitamin D) status was measured using a one-step immunoassay (Abbott Architect). Multivariable linear regression models, adjusted for age, sex, and a number of other variables, were used to estimate the time trend of vitamin D concentrations. RESULTS: The mean value of vitamin D in the entire study population was 19.9 ng/mL [standard deviation (SD) 7.9], with lower values in men (19.4 ng/mL; SD 7.5) than in women (20.5 ng/mL; SD 8.2). Using the survey in 1986 as reference category, the multivariable-adjusted mean difference [95% confidence interval (CI)] in ng/mL was 2.7 (2.2, 3.3) in 1990, 3.2 (2.7, 3.7) in 1994, 1.6 (1.0, 2.1) in 1999, − 2.0 (− 2.5, − 1.4) in 2004, 1.0 (0.4, 1.5) in 2009, and 3.1 (2.5, 3.6) in 2014. CONCLUSION: In this large cross-sectional study, we observed no clear upward or downward trend of vitamin D concentrations in northern Sweden between 1986 and 2014. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1007/s00394-019-02142-x) contains supplementary material, which is available to authorized users. Text Northern Sweden PubMed Central (PMC) Abbott ENVELOPE(-62.133,-62.133,-64.100,-64.100) European Journal of Nutrition 59 7 3037 3044 |
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English |
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Original Contribution |
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Original Contribution Summerhays, Eva Eliasson, Mats Lundqvist, Robert Söderberg, Stefan Zeller, Tanja Oskarsson, Viktor Time trends of vitamin D concentrations in northern Sweden between 1986 and 2014: a population-based cross-sectional study |
topic_facet |
Original Contribution |
description |
PURPOSE: Vitamin D, produced through cutaneous photosynthesis or ingested via foods or supplements, has generated considerable research interest due to its potential health effects. However, epidemiological data on the time trends of vitamin D status are sparse, especially from northern Europe. We examined the time trend of vitamin D concentrations in northern Sweden between 1986 and 2014. METHODS: We used data on 11,129 men and women (aged 25–74 years) from seven population-based surveys (the Northern Sweden MONICA study), recruited between 1986 and 2014. Serum vitamin D (25-hydroxyvitamin D) status was measured using a one-step immunoassay (Abbott Architect). Multivariable linear regression models, adjusted for age, sex, and a number of other variables, were used to estimate the time trend of vitamin D concentrations. RESULTS: The mean value of vitamin D in the entire study population was 19.9 ng/mL [standard deviation (SD) 7.9], with lower values in men (19.4 ng/mL; SD 7.5) than in women (20.5 ng/mL; SD 8.2). Using the survey in 1986 as reference category, the multivariable-adjusted mean difference [95% confidence interval (CI)] in ng/mL was 2.7 (2.2, 3.3) in 1990, 3.2 (2.7, 3.7) in 1994, 1.6 (1.0, 2.1) in 1999, − 2.0 (− 2.5, − 1.4) in 2004, 1.0 (0.4, 1.5) in 2009, and 3.1 (2.5, 3.6) in 2014. CONCLUSION: In this large cross-sectional study, we observed no clear upward or downward trend of vitamin D concentrations in northern Sweden between 1986 and 2014. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1007/s00394-019-02142-x) contains supplementary material, which is available to authorized users. |
format |
Text |
author |
Summerhays, Eva Eliasson, Mats Lundqvist, Robert Söderberg, Stefan Zeller, Tanja Oskarsson, Viktor |
author_facet |
Summerhays, Eva Eliasson, Mats Lundqvist, Robert Söderberg, Stefan Zeller, Tanja Oskarsson, Viktor |
author_sort |
Summerhays, Eva |
title |
Time trends of vitamin D concentrations in northern Sweden between 1986 and 2014: a population-based cross-sectional study |
title_short |
Time trends of vitamin D concentrations in northern Sweden between 1986 and 2014: a population-based cross-sectional study |
title_full |
Time trends of vitamin D concentrations in northern Sweden between 1986 and 2014: a population-based cross-sectional study |
title_fullStr |
Time trends of vitamin D concentrations in northern Sweden between 1986 and 2014: a population-based cross-sectional study |
title_full_unstemmed |
Time trends of vitamin D concentrations in northern Sweden between 1986 and 2014: a population-based cross-sectional study |
title_sort |
time trends of vitamin d concentrations in northern sweden between 1986 and 2014: a population-based cross-sectional study |
publisher |
Springer Berlin Heidelberg |
publishDate |
2019 |
url |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7501112/ http://www.ncbi.nlm.nih.gov/pubmed/31754783 https://doi.org/10.1007/s00394-019-02142-x |
long_lat |
ENVELOPE(-62.133,-62.133,-64.100,-64.100) |
geographic |
Abbott |
geographic_facet |
Abbott |
genre |
Northern Sweden |
genre_facet |
Northern Sweden |
op_source |
Eur J Nutr |
op_relation |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7501112/ http://www.ncbi.nlm.nih.gov/pubmed/31754783 http://dx.doi.org/10.1007/s00394-019-02142-x |
op_rights |
© The Author(s) 2019 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. |
op_rightsnorm |
CC-BY |
op_doi |
https://doi.org/10.1007/s00394-019-02142-x |
container_title |
European Journal of Nutrition |
container_volume |
59 |
container_issue |
7 |
container_start_page |
3037 |
op_container_end_page |
3044 |
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1766146512248635392 |