Respiratory virus disease in the Antarctic: Immunological studies
This chapter discusses the reports that men who had returned from 1.5 to 2 years isolation in Antarctica and had suffered severely from acute respiratory infections. It was surmised that this might be because of increased sensitivity to one of the common families of respiratory viruses. Two lines of...
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ftpubmed:oai:pubmedcentral.nih.gov:7152200 2023-05-15T13:32:06+02:00 Respiratory virus disease in the Antarctic: Immunological studies Holmes, M.J. 1973 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7152200/ https://doi.org/10.1016/B978-0-433-08155-5.50017-0 en eng http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7152200/ http://dx.doi.org/10.1016/B978-0-433-08155-5.50017-0 Copyright © 1973 William Heinemann Medical Books Ltd. Published by Elsevier Ltd. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active. Article Text 1973 ftpubmed https://doi.org/10.1016/B978-0-433-08155-5.50017-0 2020-04-19T00:41:20Z This chapter discusses the reports that men who had returned from 1.5 to 2 years isolation in Antarctica and had suffered severely from acute respiratory infections. It was surmised that this might be because of increased sensitivity to one of the common families of respiratory viruses. Two lines of study were therefore followed. In the first, men were examined at intervals throughout their stay in Antarctica at Stonington Island, and their titers of specific antibody against a wide range of respiratory viruses were measured throughout the isolation period. The second line of study consisted of three clinical trials in which a dose of a known respiratory virus was given to a number of subjects. The clinical and serological responses and the spread of the organism within the community were observed. The results of these investigations were compared with those of similar trials in England carried out at the Common Cold Unit at Salisbury. The results of the study suggested that it is possible to introduce a virus into a closed community, and under primitive conditions, to record its spread and the symptoms it causes. Text Antarc* Antarctic Antarctica Stonington Island PubMed Central (PMC) Antarctic Salisbury ENVELOPE(-153.617,-153.617,-85.633,-85.633) Stonington ENVELOPE(-66.997,-66.997,-68.185,-68.185) Stonington Island ENVELOPE(-67.000,-67.000,-68.183,-68.183) The Antarctic 125 134 |
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Article Holmes, M.J. Respiratory virus disease in the Antarctic: Immunological studies |
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Article |
description |
This chapter discusses the reports that men who had returned from 1.5 to 2 years isolation in Antarctica and had suffered severely from acute respiratory infections. It was surmised that this might be because of increased sensitivity to one of the common families of respiratory viruses. Two lines of study were therefore followed. In the first, men were examined at intervals throughout their stay in Antarctica at Stonington Island, and their titers of specific antibody against a wide range of respiratory viruses were measured throughout the isolation period. The second line of study consisted of three clinical trials in which a dose of a known respiratory virus was given to a number of subjects. The clinical and serological responses and the spread of the organism within the community were observed. The results of these investigations were compared with those of similar trials in England carried out at the Common Cold Unit at Salisbury. The results of the study suggested that it is possible to introduce a virus into a closed community, and under primitive conditions, to record its spread and the symptoms it causes. |
format |
Text |
author |
Holmes, M.J. |
author_facet |
Holmes, M.J. |
author_sort |
Holmes, M.J. |
title |
Respiratory virus disease in the Antarctic: Immunological studies |
title_short |
Respiratory virus disease in the Antarctic: Immunological studies |
title_full |
Respiratory virus disease in the Antarctic: Immunological studies |
title_fullStr |
Respiratory virus disease in the Antarctic: Immunological studies |
title_full_unstemmed |
Respiratory virus disease in the Antarctic: Immunological studies |
title_sort |
respiratory virus disease in the antarctic: immunological studies |
publishDate |
1973 |
url |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7152200/ https://doi.org/10.1016/B978-0-433-08155-5.50017-0 |
long_lat |
ENVELOPE(-153.617,-153.617,-85.633,-85.633) ENVELOPE(-66.997,-66.997,-68.185,-68.185) ENVELOPE(-67.000,-67.000,-68.183,-68.183) |
geographic |
Antarctic Salisbury Stonington Stonington Island The Antarctic |
geographic_facet |
Antarctic Salisbury Stonington Stonington Island The Antarctic |
genre |
Antarc* Antarctic Antarctica Stonington Island |
genre_facet |
Antarc* Antarctic Antarctica Stonington Island |
op_relation |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7152200/ http://dx.doi.org/10.1016/B978-0-433-08155-5.50017-0 |
op_rights |
Copyright © 1973 William Heinemann Medical Books Ltd. Published by Elsevier Ltd. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active. |
op_doi |
https://doi.org/10.1016/B978-0-433-08155-5.50017-0 |
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