Is there a seasonal variation of survival after systemic chemotherapy for metastatic castration-resistant prostate cancer in a rural part of North Norway?

• Published in: International Journal of Circumpolar Health
• Main Authors: Nieder, Carsten, Dalhaug, Astrid, Haukland, Ellinor
• Format: Text
• Language: English
• Published: Taylor & Francis 2020
• Subjects: Original Research Article; Bodø; Norway; Nordland; North Norway; polar night
• Online Access: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7144237/; http://www.ncbi.nlm.nih.gov/pubmed/32191614; https://doi.org/10.1080/22423982.2020.1742520

The winter darkness or polar night induces endocrine and metabolic mechanisms, which might reduce the efficacy of cancer treatment and thus contribute to shorter survival. Moreover, season-and weather-related treatment delays and irregularities might also cause reduced efficacy of anti-cancer drugs....