A comparison of individual-level vs. hypothetically pooled mercury biomonitoring data from the Maternal Organics Monitoring Study (MOMS), Alaska, 1999-2012
Biomonitoring for heavy metals is important to assess health risks, especially in Arctic communities where rural residents rely on locally harvested foods. However, laboratory testing for blood contaminants is expensive and might not be sustainable for long-term monitoring. We assessed whether poole...
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Online Access: | http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7034428/ http://www.ncbi.nlm.nih.gov/pubmed/32039659 https://doi.org/10.1080/22423982.2020.1726256 |
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ftpubmed:oai:pubmedcentral.nih.gov:7034428 2023-05-15T14:57:16+02:00 A comparison of individual-level vs. hypothetically pooled mercury biomonitoring data from the Maternal Organics Monitoring Study (MOMS), Alaska, 1999-2012 Mosites, Emily Rodriguez, Ernesto Caudill, Samuel P. Hennessy, Thomas W. Berner, James 2020-02-10 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7034428/ http://www.ncbi.nlm.nih.gov/pubmed/32039659 https://doi.org/10.1080/22423982.2020.1726256 en eng Taylor & Francis http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7034428/ http://www.ncbi.nlm.nih.gov/pubmed/32039659 http://dx.doi.org/10.1080/22423982.2020.1726256 © 2020 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group. http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. CC-BY-NC Original Research Article Text 2020 ftpubmed https://doi.org/10.1080/22423982.2020.1726256 2020-03-08T01:34:44Z Biomonitoring for heavy metals is important to assess health risks, especially in Arctic communities where rural residents rely on locally harvested foods. However, laboratory testing for blood contaminants is expensive and might not be sustainable for long-term monitoring. We assessed whether pooled specimen biomonitoring could be a part of a plan for blood contaminant surveillance among pregnant women in rural Alaska using existing blood mercury level data from three cross sectional studies of pregnant women. We applied a hypothetical pooled specimen template stratified into 8 demographic groups based on age, coastal or inland residence, and pre-pregnancy weight. The hypothetical geometric mean blood mercury levels were similar to the individual-level geometric means. However, the 95% confidence intervals were much wider for the hypothetical geometric means compared to the true geometric means. Although the variability that resulted from pooling specimens using a small sample made it difficult to compare demographic groups to each other, pooled specimen results could be an accurate reflection of the population burden of mercury contamination in the Arctic in the context of large numbers of biomonitoring samples. Text Arctic Alaska PubMed Central (PMC) Arctic International Journal of Circumpolar Health 79 1 1726256 |
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Original Research Article Mosites, Emily Rodriguez, Ernesto Caudill, Samuel P. Hennessy, Thomas W. Berner, James A comparison of individual-level vs. hypothetically pooled mercury biomonitoring data from the Maternal Organics Monitoring Study (MOMS), Alaska, 1999-2012 |
topic_facet |
Original Research Article |
description |
Biomonitoring for heavy metals is important to assess health risks, especially in Arctic communities where rural residents rely on locally harvested foods. However, laboratory testing for blood contaminants is expensive and might not be sustainable for long-term monitoring. We assessed whether pooled specimen biomonitoring could be a part of a plan for blood contaminant surveillance among pregnant women in rural Alaska using existing blood mercury level data from three cross sectional studies of pregnant women. We applied a hypothetical pooled specimen template stratified into 8 demographic groups based on age, coastal or inland residence, and pre-pregnancy weight. The hypothetical geometric mean blood mercury levels were similar to the individual-level geometric means. However, the 95% confidence intervals were much wider for the hypothetical geometric means compared to the true geometric means. Although the variability that resulted from pooling specimens using a small sample made it difficult to compare demographic groups to each other, pooled specimen results could be an accurate reflection of the population burden of mercury contamination in the Arctic in the context of large numbers of biomonitoring samples. |
format |
Text |
author |
Mosites, Emily Rodriguez, Ernesto Caudill, Samuel P. Hennessy, Thomas W. Berner, James |
author_facet |
Mosites, Emily Rodriguez, Ernesto Caudill, Samuel P. Hennessy, Thomas W. Berner, James |
author_sort |
Mosites, Emily |
title |
A comparison of individual-level vs. hypothetically pooled mercury biomonitoring data from the Maternal Organics Monitoring Study (MOMS), Alaska, 1999-2012 |
title_short |
A comparison of individual-level vs. hypothetically pooled mercury biomonitoring data from the Maternal Organics Monitoring Study (MOMS), Alaska, 1999-2012 |
title_full |
A comparison of individual-level vs. hypothetically pooled mercury biomonitoring data from the Maternal Organics Monitoring Study (MOMS), Alaska, 1999-2012 |
title_fullStr |
A comparison of individual-level vs. hypothetically pooled mercury biomonitoring data from the Maternal Organics Monitoring Study (MOMS), Alaska, 1999-2012 |
title_full_unstemmed |
A comparison of individual-level vs. hypothetically pooled mercury biomonitoring data from the Maternal Organics Monitoring Study (MOMS), Alaska, 1999-2012 |
title_sort |
comparison of individual-level vs. hypothetically pooled mercury biomonitoring data from the maternal organics monitoring study (moms), alaska, 1999-2012 |
publisher |
Taylor & Francis |
publishDate |
2020 |
url |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7034428/ http://www.ncbi.nlm.nih.gov/pubmed/32039659 https://doi.org/10.1080/22423982.2020.1726256 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic Alaska |
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Arctic Alaska |
op_relation |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7034428/ http://www.ncbi.nlm.nih.gov/pubmed/32039659 http://dx.doi.org/10.1080/22423982.2020.1726256 |
op_rights |
© 2020 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group. http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
op_rightsnorm |
CC-BY-NC |
op_doi |
https://doi.org/10.1080/22423982.2020.1726256 |
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International Journal of Circumpolar Health |
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79 |
container_issue |
1 |
container_start_page |
1726256 |
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1766329360290152448 |