Chemical Diversity in Species Belonging to Soft Coral Genus Sacrophyton and Its Impact on Biological Activity: A Review
One of the most widely distributed soft coral species, found especially in shallow waters of the Indo-Pacific region, Red Sea, Mediterranean Sea, and also the Arctic, is genus Sacrophyton. The total number of species belonging to it was estimated to be 40. Sarcophyton species are considered to be a...
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ftpubmed:oai:pubmedcentral.nih.gov:7024209 2023-05-15T15:04:41+02:00 Chemical Diversity in Species Belonging to Soft Coral Genus Sacrophyton and Its Impact on Biological Activity: A Review Elkhawas, Yasmin A. Elissawy, Ahmed M. Elnaggar, Mohamed S. Mostafa, Nada M. Al-Sayed, Eman Bishr, Mokhtar M. Singab, Abdel Nasser B. Salama, Osama M. 2020-01-06 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7024209/ http://www.ncbi.nlm.nih.gov/pubmed/31935862 https://doi.org/10.3390/md18010041 en eng MDPI http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7024209/ http://www.ncbi.nlm.nih.gov/pubmed/31935862 http://dx.doi.org/10.3390/md18010041 © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). CC-BY Review Text 2020 ftpubmed https://doi.org/10.3390/md18010041 2020-03-22T01:21:50Z One of the most widely distributed soft coral species, found especially in shallow waters of the Indo-Pacific region, Red Sea, Mediterranean Sea, and also the Arctic, is genus Sacrophyton. The total number of species belonging to it was estimated to be 40. Sarcophyton species are considered to be a reservoir of bioactive natural metabolites. Secondary metabolites isolated from members belonging to this genus show great chemical diversity. They are rich in terpenoids, in particular, cembranoids diterpenes, tetratepenoids, triterpenoids, and ceramide, in addition to steroids, sesquiterpenes, and fatty acids. They showed a broad range of potent biological activities, such as antitumor, neuroprotective, antimicrobial, antiviral, antidiabetic, antifouling, and anti-inflammatory activity. This review presents all isolated secondary metabolites from species of genera Sacrophyton, as well as their reported biological activities covering a period of about two decades (1998–2019). It deals with 481 metabolites, including 323 diterpenes, 39 biscembranoids, 11 sesquiterpenes, 53 polyoxygenated sterols, and 55 miscellaneous and their pharmacological activities. Text Arctic PubMed Central (PMC) Arctic Pacific Marine Drugs 18 1 41 |
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Review Elkhawas, Yasmin A. Elissawy, Ahmed M. Elnaggar, Mohamed S. Mostafa, Nada M. Al-Sayed, Eman Bishr, Mokhtar M. Singab, Abdel Nasser B. Salama, Osama M. Chemical Diversity in Species Belonging to Soft Coral Genus Sacrophyton and Its Impact on Biological Activity: A Review |
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Review |
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One of the most widely distributed soft coral species, found especially in shallow waters of the Indo-Pacific region, Red Sea, Mediterranean Sea, and also the Arctic, is genus Sacrophyton. The total number of species belonging to it was estimated to be 40. Sarcophyton species are considered to be a reservoir of bioactive natural metabolites. Secondary metabolites isolated from members belonging to this genus show great chemical diversity. They are rich in terpenoids, in particular, cembranoids diterpenes, tetratepenoids, triterpenoids, and ceramide, in addition to steroids, sesquiterpenes, and fatty acids. They showed a broad range of potent biological activities, such as antitumor, neuroprotective, antimicrobial, antiviral, antidiabetic, antifouling, and anti-inflammatory activity. This review presents all isolated secondary metabolites from species of genera Sacrophyton, as well as their reported biological activities covering a period of about two decades (1998–2019). It deals with 481 metabolites, including 323 diterpenes, 39 biscembranoids, 11 sesquiterpenes, 53 polyoxygenated sterols, and 55 miscellaneous and their pharmacological activities. |
format |
Text |
author |
Elkhawas, Yasmin A. Elissawy, Ahmed M. Elnaggar, Mohamed S. Mostafa, Nada M. Al-Sayed, Eman Bishr, Mokhtar M. Singab, Abdel Nasser B. Salama, Osama M. |
author_facet |
Elkhawas, Yasmin A. Elissawy, Ahmed M. Elnaggar, Mohamed S. Mostafa, Nada M. Al-Sayed, Eman Bishr, Mokhtar M. Singab, Abdel Nasser B. Salama, Osama M. |
author_sort |
Elkhawas, Yasmin A. |
title |
Chemical Diversity in Species Belonging to Soft Coral Genus Sacrophyton and Its Impact on Biological Activity: A Review |
title_short |
Chemical Diversity in Species Belonging to Soft Coral Genus Sacrophyton and Its Impact on Biological Activity: A Review |
title_full |
Chemical Diversity in Species Belonging to Soft Coral Genus Sacrophyton and Its Impact on Biological Activity: A Review |
title_fullStr |
Chemical Diversity in Species Belonging to Soft Coral Genus Sacrophyton and Its Impact on Biological Activity: A Review |
title_full_unstemmed |
Chemical Diversity in Species Belonging to Soft Coral Genus Sacrophyton and Its Impact on Biological Activity: A Review |
title_sort |
chemical diversity in species belonging to soft coral genus sacrophyton and its impact on biological activity: a review |
publisher |
MDPI |
publishDate |
2020 |
url |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7024209/ http://www.ncbi.nlm.nih.gov/pubmed/31935862 https://doi.org/10.3390/md18010041 |
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Arctic Pacific |
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Arctic Pacific |
genre |
Arctic |
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Arctic |
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7024209/ http://www.ncbi.nlm.nih.gov/pubmed/31935862 http://dx.doi.org/10.3390/md18010041 |
op_rights |
© 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
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CC-BY |
op_doi |
https://doi.org/10.3390/md18010041 |
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Marine Drugs |
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18 |
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1 |
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41 |
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