Kidney disease and care among First Nations people with diabetes in Ontario: a population-based cohort study
BACKGROUND: End-stage kidney disease is a serious complication of diabetes. We describe the prevalence of chronic kidney disease, prevalence and incidence of end-stage kidney disease and quality of care of early-stage chronic kidney disease for First Nations people with diabetes compared to other On...
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ftpubmed:oai:pubmedcentral.nih.gov:7015672 2023-05-15T16:14:08+02:00 Kidney disease and care among First Nations people with diabetes in Ontario: a population-based cohort study Nash, Danielle M. Dirk, Jade S. McArthur, Eric Green, Michael E. Shah, Baiju R. Walker, Jennifer D. Beaucage, Mary Jones, Carmen R. Garg, Amit X. 2019-12-02 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7015672/ http://www.ncbi.nlm.nih.gov/pubmed/31822501 https://doi.org/10.9778/cmajo.20190164 en eng Joule Inc. or its licensors http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7015672/ http://www.ncbi.nlm.nih.gov/pubmed/31822501 http://dx.doi.org/10.9778/cmajo.20190164 Copyright 2019, Joule Inc. or its licensors Research Text 2019 ftpubmed https://doi.org/10.9778/cmajo.20190164 2020-03-15T01:20:20Z BACKGROUND: End-stage kidney disease is a serious complication of diabetes. We describe the prevalence of chronic kidney disease, prevalence and incidence of end-stage kidney disease and quality of care of early-stage chronic kidney disease for First Nations people with diabetes compared to other Ontarians with diabetes. METHODS: We conducted a retrospective cohort study in Ontario using linked administrative data at ICES. We included adults with incident diabetes between 1994 and 2014, and used laboratory values to identify kidney disease and quality indicators for care for early-stage disease. We compared measures in First Nations people to those in other people in Ontario, and used direct age and sex standardization. We used Cox proportional hazards regression to compare the incidence of end-stage kidney disease between groups. RESULTS: Our study included 21 968 First Nations people with diabetes. The age- and sex-standardized prevalence of chronic kidney disease was higher for First Nations people than for other Ontarians (20.7% v. 18.4%), as was the prevalence of end-stage kidney disease (2.9% v. 1.0%). The incidence of end-stage kidney disease was higher among First Nations people than among other people in Ontario (9.3 v. 4.7 events per 10 000 person-years; age- and sex-adjusted hazard ratio 2.23, 95% confidence interval 1.72–2.89). The 2 groups were similarly likely to receive recommended medications, but First Nations people were less likely to receive laboratory tests for their kidney disease. INTERPRETATION: Despite receiving similar quality of care for early-stage kidney disease, First Nations people with diabetes had higher rates of end-stage kidney disease than other Ontarians. Further research is needed to better understand contributing factors to help inform future interventions. Text First Nations PubMed Central (PMC) CMAJ Open 7 4 E706 E712 |
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Research Nash, Danielle M. Dirk, Jade S. McArthur, Eric Green, Michael E. Shah, Baiju R. Walker, Jennifer D. Beaucage, Mary Jones, Carmen R. Garg, Amit X. Kidney disease and care among First Nations people with diabetes in Ontario: a population-based cohort study |
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Research |
description |
BACKGROUND: End-stage kidney disease is a serious complication of diabetes. We describe the prevalence of chronic kidney disease, prevalence and incidence of end-stage kidney disease and quality of care of early-stage chronic kidney disease for First Nations people with diabetes compared to other Ontarians with diabetes. METHODS: We conducted a retrospective cohort study in Ontario using linked administrative data at ICES. We included adults with incident diabetes between 1994 and 2014, and used laboratory values to identify kidney disease and quality indicators for care for early-stage disease. We compared measures in First Nations people to those in other people in Ontario, and used direct age and sex standardization. We used Cox proportional hazards regression to compare the incidence of end-stage kidney disease between groups. RESULTS: Our study included 21 968 First Nations people with diabetes. The age- and sex-standardized prevalence of chronic kidney disease was higher for First Nations people than for other Ontarians (20.7% v. 18.4%), as was the prevalence of end-stage kidney disease (2.9% v. 1.0%). The incidence of end-stage kidney disease was higher among First Nations people than among other people in Ontario (9.3 v. 4.7 events per 10 000 person-years; age- and sex-adjusted hazard ratio 2.23, 95% confidence interval 1.72–2.89). The 2 groups were similarly likely to receive recommended medications, but First Nations people were less likely to receive laboratory tests for their kidney disease. INTERPRETATION: Despite receiving similar quality of care for early-stage kidney disease, First Nations people with diabetes had higher rates of end-stage kidney disease than other Ontarians. Further research is needed to better understand contributing factors to help inform future interventions. |
format |
Text |
author |
Nash, Danielle M. Dirk, Jade S. McArthur, Eric Green, Michael E. Shah, Baiju R. Walker, Jennifer D. Beaucage, Mary Jones, Carmen R. Garg, Amit X. |
author_facet |
Nash, Danielle M. Dirk, Jade S. McArthur, Eric Green, Michael E. Shah, Baiju R. Walker, Jennifer D. Beaucage, Mary Jones, Carmen R. Garg, Amit X. |
author_sort |
Nash, Danielle M. |
title |
Kidney disease and care among First Nations people with diabetes in Ontario: a population-based cohort study |
title_short |
Kidney disease and care among First Nations people with diabetes in Ontario: a population-based cohort study |
title_full |
Kidney disease and care among First Nations people with diabetes in Ontario: a population-based cohort study |
title_fullStr |
Kidney disease and care among First Nations people with diabetes in Ontario: a population-based cohort study |
title_full_unstemmed |
Kidney disease and care among First Nations people with diabetes in Ontario: a population-based cohort study |
title_sort |
kidney disease and care among first nations people with diabetes in ontario: a population-based cohort study |
publisher |
Joule Inc. or its licensors |
publishDate |
2019 |
url |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7015672/ http://www.ncbi.nlm.nih.gov/pubmed/31822501 https://doi.org/10.9778/cmajo.20190164 |
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First Nations |
genre_facet |
First Nations |
op_relation |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7015672/ http://www.ncbi.nlm.nih.gov/pubmed/31822501 http://dx.doi.org/10.9778/cmajo.20190164 |
op_rights |
Copyright 2019, Joule Inc. or its licensors |
op_doi |
https://doi.org/10.9778/cmajo.20190164 |
container_title |
CMAJ Open |
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7 |
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4 |
container_start_page |
E706 |
op_container_end_page |
E712 |
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1765999969236418560 |