Antibiotic use among twelve Canadian First Nations communities: a retrospective chart review of skin and soft tissue infections
BACKGROUND: Previous publications indicated an emerging issue with community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA), particularly skin and soft tissue infections (SSTIs), in Indigenous communities in Canada. The objectives of this analysis were to explore the prevalence of SS...
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ftpubmed:oai:pubmedcentral.nih.gov:7011559 2023-05-15T16:16:04+02:00 Antibiotic use among twelve Canadian First Nations communities: a retrospective chart review of skin and soft tissue infections Jeong, Dahn Nguyen, Ha Nhan Thi Tyndall, Mark Schreiber, Yoko S. 2020-02-10 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7011559/ http://www.ncbi.nlm.nih.gov/pubmed/32041554 https://doi.org/10.1186/s12879-020-4842-1 en eng BioMed Central http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7011559/ http://www.ncbi.nlm.nih.gov/pubmed/32041554 http://dx.doi.org/10.1186/s12879-020-4842-1 © The Author(s). 2020 Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. CC0 PDM CC-BY Research Article Text 2020 ftpubmed https://doi.org/10.1186/s12879-020-4842-1 2020-02-23T01:23:32Z BACKGROUND: Previous publications indicated an emerging issue with community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA), particularly skin and soft tissue infections (SSTIs), in Indigenous communities in Canada. The objectives of this analysis were to explore the prevalence of SSTIs due to CA-MRSA and patterns of antimicrobial use in the community setting. METHODS: A retrospective chart review was conducted as part of an environmental scan to assess antibiotic prescriptions in 12 First Nations communities across five provinces in Canada including Alberta, Saskatchewan, Manitoba, Ontario, and Québec. Charts were randomly selected from nursing stations and patients who had accessed care in the previous 12 months and were ≥ 18 years were included in the review. Data was collected from September to December, 2013 on antibiotic prescriptions, including SSTIs, clinical symptoms, diagnostic information including presence of CA-MRSA infection, and treatment. RESULTS: A total of 372 charts were reviewed, 60 from Alberta, 70 from Saskatchewan, 120 from Manitoba, 100 from Ontario, and 22 from Québec. Among 372 patients, 224 (60.2%) patients had at least one antibiotic prescription in the previous 12 months and 569 prescriptions were written in total. The prevalence of SSTIs was estimated at 36.8% (137 cases of SSTIs in 372 charts reviewed). In 137 cases of SSTIs, 34 (24.8%) were purulent infections, and 55 (40.2%) were due to CA-MRSA. CONCLUSIONS: This study has identified a high prevalence of antibiotic use and SSTIs due to CA-MRSA in remote and isolated Indigenous communities across Canada. This population is currently hard to reach and under-represented in standard surveillance system and randomized retrospective chart reviews can offer complimentary methodology for monitoring disease burden, treatment and prevention. Text First Nations PubMed Central (PMC) Canada BMC Infectious Diseases 20 1 |
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Research Article Jeong, Dahn Nguyen, Ha Nhan Thi Tyndall, Mark Schreiber, Yoko S. Antibiotic use among twelve Canadian First Nations communities: a retrospective chart review of skin and soft tissue infections |
topic_facet |
Research Article |
description |
BACKGROUND: Previous publications indicated an emerging issue with community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA), particularly skin and soft tissue infections (SSTIs), in Indigenous communities in Canada. The objectives of this analysis were to explore the prevalence of SSTIs due to CA-MRSA and patterns of antimicrobial use in the community setting. METHODS: A retrospective chart review was conducted as part of an environmental scan to assess antibiotic prescriptions in 12 First Nations communities across five provinces in Canada including Alberta, Saskatchewan, Manitoba, Ontario, and Québec. Charts were randomly selected from nursing stations and patients who had accessed care in the previous 12 months and were ≥ 18 years were included in the review. Data was collected from September to December, 2013 on antibiotic prescriptions, including SSTIs, clinical symptoms, diagnostic information including presence of CA-MRSA infection, and treatment. RESULTS: A total of 372 charts were reviewed, 60 from Alberta, 70 from Saskatchewan, 120 from Manitoba, 100 from Ontario, and 22 from Québec. Among 372 patients, 224 (60.2%) patients had at least one antibiotic prescription in the previous 12 months and 569 prescriptions were written in total. The prevalence of SSTIs was estimated at 36.8% (137 cases of SSTIs in 372 charts reviewed). In 137 cases of SSTIs, 34 (24.8%) were purulent infections, and 55 (40.2%) were due to CA-MRSA. CONCLUSIONS: This study has identified a high prevalence of antibiotic use and SSTIs due to CA-MRSA in remote and isolated Indigenous communities across Canada. This population is currently hard to reach and under-represented in standard surveillance system and randomized retrospective chart reviews can offer complimentary methodology for monitoring disease burden, treatment and prevention. |
format |
Text |
author |
Jeong, Dahn Nguyen, Ha Nhan Thi Tyndall, Mark Schreiber, Yoko S. |
author_facet |
Jeong, Dahn Nguyen, Ha Nhan Thi Tyndall, Mark Schreiber, Yoko S. |
author_sort |
Jeong, Dahn |
title |
Antibiotic use among twelve Canadian First Nations communities: a retrospective chart review of skin and soft tissue infections |
title_short |
Antibiotic use among twelve Canadian First Nations communities: a retrospective chart review of skin and soft tissue infections |
title_full |
Antibiotic use among twelve Canadian First Nations communities: a retrospective chart review of skin and soft tissue infections |
title_fullStr |
Antibiotic use among twelve Canadian First Nations communities: a retrospective chart review of skin and soft tissue infections |
title_full_unstemmed |
Antibiotic use among twelve Canadian First Nations communities: a retrospective chart review of skin and soft tissue infections |
title_sort |
antibiotic use among twelve canadian first nations communities: a retrospective chart review of skin and soft tissue infections |
publisher |
BioMed Central |
publishDate |
2020 |
url |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7011559/ http://www.ncbi.nlm.nih.gov/pubmed/32041554 https://doi.org/10.1186/s12879-020-4842-1 |
geographic |
Canada |
geographic_facet |
Canada |
genre |
First Nations |
genre_facet |
First Nations |
op_relation |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7011559/ http://www.ncbi.nlm.nih.gov/pubmed/32041554 http://dx.doi.org/10.1186/s12879-020-4842-1 |
op_rights |
© The Author(s). 2020 Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
op_rightsnorm |
CC0 PDM CC-BY |
op_doi |
https://doi.org/10.1186/s12879-020-4842-1 |
container_title |
BMC Infectious Diseases |
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20 |
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1 |
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1766001927540178944 |