Neonatal Vitamin A Deficiency and Its Impact on Acute Respiratory Infections among Preschool Inuit Children

OBJECTIVE: To assess if vitamin A concentration in umbilical cord blood is associated with incidence and severity of respiratory infections in preschool Inuit children from Nunavik (Québec, Canada). METHOD: The medical charts of 305 children were reviewed from 0 to 5 years of age. The association be...

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Published in:Canadian Journal of Public Health
Main Authors: Cameron, Cynthia, Dallaire, Frédéric, Vézina, Carole, Muckle, Gina, Bruneau, Suzanne, Ayotte, Pierre, Dewailly, Eric
Format: Text
Language:English
Published: Springer International Publishing 2008
Subjects:
Online Access:http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6975672/
http://www.ncbi.nlm.nih.gov/pubmed/18457282
https://doi.org/10.1007/BF03405454
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spelling ftpubmed:oai:pubmedcentral.nih.gov:6975672 2023-05-15T16:54:55+02:00 Neonatal Vitamin A Deficiency and Its Impact on Acute Respiratory Infections among Preschool Inuit Children Cameron, Cynthia Dallaire, Frédéric Vézina, Carole Muckle, Gina Bruneau, Suzanne Ayotte, Pierre Dewailly, Eric 2008-03-01 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6975672/ http://www.ncbi.nlm.nih.gov/pubmed/18457282 https://doi.org/10.1007/BF03405454 en eng Springer International Publishing http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6975672/ http://www.ncbi.nlm.nih.gov/pubmed/18457282 http://dx.doi.org/10.1007/BF03405454 © The Canadian Public Health Association 2008 Article Text 2008 ftpubmed https://doi.org/10.1007/BF03405454 2020-02-09T01:22:10Z OBJECTIVE: To assess if vitamin A concentration in umbilical cord blood is associated with incidence and severity of respiratory infections in preschool Inuit children from Nunavik (Québec, Canada). METHOD: The medical charts of 305 children were reviewed from 0 to 5 years of age. The association between vitamin A concentration in umbilical cord plasma and the incidence rates of acute otitis media (AOM), lower respiratory tract infections (LRTIs) and hospitalization rates for LRTIs was evaluated using Poisson regression. RESULTS: Compared to children with vitamin A concentration >-20 μg/dl, adjusted rate ratios (RR) for children below 20 μg/dl ranged between 1.06–1.62 for AOM, 1.12–1.34 for LRTIs, and 1.09–1.43 for hospitalization for LRTIs. Most RRs were statistically significant for AOM and LRTIs, but not for hospitalization for LRTIs. CONCLUSION: Neonatal vitamin A deficiency appears to be a significant risk factor for AOM and LRTIs in this population. Text inuit Nunavik PubMed Central (PMC) Canada Nunavik Canadian Journal of Public Health 99 2 102 106
institution Open Polar
collection PubMed Central (PMC)
op_collection_id ftpubmed
language English
topic Article
spellingShingle Article
Cameron, Cynthia
Dallaire, Frédéric
Vézina, Carole
Muckle, Gina
Bruneau, Suzanne
Ayotte, Pierre
Dewailly, Eric
Neonatal Vitamin A Deficiency and Its Impact on Acute Respiratory Infections among Preschool Inuit Children
topic_facet Article
description OBJECTIVE: To assess if vitamin A concentration in umbilical cord blood is associated with incidence and severity of respiratory infections in preschool Inuit children from Nunavik (Québec, Canada). METHOD: The medical charts of 305 children were reviewed from 0 to 5 years of age. The association between vitamin A concentration in umbilical cord plasma and the incidence rates of acute otitis media (AOM), lower respiratory tract infections (LRTIs) and hospitalization rates for LRTIs was evaluated using Poisson regression. RESULTS: Compared to children with vitamin A concentration >-20 μg/dl, adjusted rate ratios (RR) for children below 20 μg/dl ranged between 1.06–1.62 for AOM, 1.12–1.34 for LRTIs, and 1.09–1.43 for hospitalization for LRTIs. Most RRs were statistically significant for AOM and LRTIs, but not for hospitalization for LRTIs. CONCLUSION: Neonatal vitamin A deficiency appears to be a significant risk factor for AOM and LRTIs in this population.
format Text
author Cameron, Cynthia
Dallaire, Frédéric
Vézina, Carole
Muckle, Gina
Bruneau, Suzanne
Ayotte, Pierre
Dewailly, Eric
author_facet Cameron, Cynthia
Dallaire, Frédéric
Vézina, Carole
Muckle, Gina
Bruneau, Suzanne
Ayotte, Pierre
Dewailly, Eric
author_sort Cameron, Cynthia
title Neonatal Vitamin A Deficiency and Its Impact on Acute Respiratory Infections among Preschool Inuit Children
title_short Neonatal Vitamin A Deficiency and Its Impact on Acute Respiratory Infections among Preschool Inuit Children
title_full Neonatal Vitamin A Deficiency and Its Impact on Acute Respiratory Infections among Preschool Inuit Children
title_fullStr Neonatal Vitamin A Deficiency and Its Impact on Acute Respiratory Infections among Preschool Inuit Children
title_full_unstemmed Neonatal Vitamin A Deficiency and Its Impact on Acute Respiratory Infections among Preschool Inuit Children
title_sort neonatal vitamin a deficiency and its impact on acute respiratory infections among preschool inuit children
publisher Springer International Publishing
publishDate 2008
url http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6975672/
http://www.ncbi.nlm.nih.gov/pubmed/18457282
https://doi.org/10.1007/BF03405454
geographic Canada
Nunavik
geographic_facet Canada
Nunavik
genre inuit
Nunavik
genre_facet inuit
Nunavik
op_relation http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6975672/
http://www.ncbi.nlm.nih.gov/pubmed/18457282
http://dx.doi.org/10.1007/BF03405454
op_rights © The Canadian Public Health Association 2008
op_doi https://doi.org/10.1007/BF03405454
container_title Canadian Journal of Public Health
container_volume 99
container_issue 2
container_start_page 102
op_container_end_page 106
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