Neonatal Vitamin A Deficiency and Its Impact on Acute Respiratory Infections among Preschool Inuit Children
OBJECTIVE: To assess if vitamin A concentration in umbilical cord blood is associated with incidence and severity of respiratory infections in preschool Inuit children from Nunavik (Québec, Canada). METHOD: The medical charts of 305 children were reviewed from 0 to 5 years of age. The association be...
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ftpubmed:oai:pubmedcentral.nih.gov:6975672 2023-05-15T16:54:55+02:00 Neonatal Vitamin A Deficiency and Its Impact on Acute Respiratory Infections among Preschool Inuit Children Cameron, Cynthia Dallaire, Frédéric Vézina, Carole Muckle, Gina Bruneau, Suzanne Ayotte, Pierre Dewailly, Eric 2008-03-01 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6975672/ http://www.ncbi.nlm.nih.gov/pubmed/18457282 https://doi.org/10.1007/BF03405454 en eng Springer International Publishing http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6975672/ http://www.ncbi.nlm.nih.gov/pubmed/18457282 http://dx.doi.org/10.1007/BF03405454 © The Canadian Public Health Association 2008 Article Text 2008 ftpubmed https://doi.org/10.1007/BF03405454 2020-02-09T01:22:10Z OBJECTIVE: To assess if vitamin A concentration in umbilical cord blood is associated with incidence and severity of respiratory infections in preschool Inuit children from Nunavik (Québec, Canada). METHOD: The medical charts of 305 children were reviewed from 0 to 5 years of age. The association between vitamin A concentration in umbilical cord plasma and the incidence rates of acute otitis media (AOM), lower respiratory tract infections (LRTIs) and hospitalization rates for LRTIs was evaluated using Poisson regression. RESULTS: Compared to children with vitamin A concentration >-20 μg/dl, adjusted rate ratios (RR) for children below 20 μg/dl ranged between 1.06–1.62 for AOM, 1.12–1.34 for LRTIs, and 1.09–1.43 for hospitalization for LRTIs. Most RRs were statistically significant for AOM and LRTIs, but not for hospitalization for LRTIs. CONCLUSION: Neonatal vitamin A deficiency appears to be a significant risk factor for AOM and LRTIs in this population. Text inuit Nunavik PubMed Central (PMC) Canada Nunavik Canadian Journal of Public Health 99 2 102 106 |
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Article Cameron, Cynthia Dallaire, Frédéric Vézina, Carole Muckle, Gina Bruneau, Suzanne Ayotte, Pierre Dewailly, Eric Neonatal Vitamin A Deficiency and Its Impact on Acute Respiratory Infections among Preschool Inuit Children |
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OBJECTIVE: To assess if vitamin A concentration in umbilical cord blood is associated with incidence and severity of respiratory infections in preschool Inuit children from Nunavik (Québec, Canada). METHOD: The medical charts of 305 children were reviewed from 0 to 5 years of age. The association between vitamin A concentration in umbilical cord plasma and the incidence rates of acute otitis media (AOM), lower respiratory tract infections (LRTIs) and hospitalization rates for LRTIs was evaluated using Poisson regression. RESULTS: Compared to children with vitamin A concentration >-20 μg/dl, adjusted rate ratios (RR) for children below 20 μg/dl ranged between 1.06–1.62 for AOM, 1.12–1.34 for LRTIs, and 1.09–1.43 for hospitalization for LRTIs. Most RRs were statistically significant for AOM and LRTIs, but not for hospitalization for LRTIs. CONCLUSION: Neonatal vitamin A deficiency appears to be a significant risk factor for AOM and LRTIs in this population. |
format |
Text |
author |
Cameron, Cynthia Dallaire, Frédéric Vézina, Carole Muckle, Gina Bruneau, Suzanne Ayotte, Pierre Dewailly, Eric |
author_facet |
Cameron, Cynthia Dallaire, Frédéric Vézina, Carole Muckle, Gina Bruneau, Suzanne Ayotte, Pierre Dewailly, Eric |
author_sort |
Cameron, Cynthia |
title |
Neonatal Vitamin A Deficiency and Its Impact on Acute Respiratory Infections among Preschool Inuit Children |
title_short |
Neonatal Vitamin A Deficiency and Its Impact on Acute Respiratory Infections among Preschool Inuit Children |
title_full |
Neonatal Vitamin A Deficiency and Its Impact on Acute Respiratory Infections among Preschool Inuit Children |
title_fullStr |
Neonatal Vitamin A Deficiency and Its Impact on Acute Respiratory Infections among Preschool Inuit Children |
title_full_unstemmed |
Neonatal Vitamin A Deficiency and Its Impact on Acute Respiratory Infections among Preschool Inuit Children |
title_sort |
neonatal vitamin a deficiency and its impact on acute respiratory infections among preschool inuit children |
publisher |
Springer International Publishing |
publishDate |
2008 |
url |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6975672/ http://www.ncbi.nlm.nih.gov/pubmed/18457282 https://doi.org/10.1007/BF03405454 |
geographic |
Canada Nunavik |
geographic_facet |
Canada Nunavik |
genre |
inuit Nunavik |
genre_facet |
inuit Nunavik |
op_relation |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6975672/ http://www.ncbi.nlm.nih.gov/pubmed/18457282 http://dx.doi.org/10.1007/BF03405454 |
op_rights |
© The Canadian Public Health Association 2008 |
op_doi |
https://doi.org/10.1007/BF03405454 |
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Canadian Journal of Public Health |
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99 |
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2 |
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102 |
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106 |
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1766045849640501248 |