First evaluation of resistance to both a California OsHV-1 variant and a French OsHV-1 microvariant in Pacific oysters
BACKGROUND: Variants of the Ostreid herpesvirus 1 (OsHV-1) cause high losses of Pacific oysters globally, including in Tomales Bay, California, USA. A suite of new variants, the OsHV-1 microvariants (μvars), cause very high mortalities of Pacific oysters in major oyster-growing regions outside of th...
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ftpubmed:oai:pubmedcentral.nih.gov:6909534 2023-05-15T17:54:20+02:00 First evaluation of resistance to both a California OsHV-1 variant and a French OsHV-1 microvariant in Pacific oysters Divilov, Konstantin Schoolfield, Blaine Morga, Benjamin Dégremont, Lionel Burge, Colleen A. Mancilla Cortez, Daniel Friedman, Carolyn S. Fleener, Gary B. Dumbauld, Brett R. Langdon, Chris 2019-12-12 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6909534/ http://www.ncbi.nlm.nih.gov/pubmed/31830898 https://doi.org/10.1186/s12863-019-0791-3 en eng BioMed Central http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6909534/ http://www.ncbi.nlm.nih.gov/pubmed/31830898 http://dx.doi.org/10.1186/s12863-019-0791-3 © The Author(s). 2019 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. CC0 PDM CC-BY Research Article Text 2019 ftpubmed https://doi.org/10.1186/s12863-019-0791-3 2019-12-22T01:26:38Z BACKGROUND: Variants of the Ostreid herpesvirus 1 (OsHV-1) cause high losses of Pacific oysters globally, including in Tomales Bay, California, USA. A suite of new variants, the OsHV-1 microvariants (μvars), cause very high mortalities of Pacific oysters in major oyster-growing regions outside of the United States. There are currently no known Pacific oysters in the United States that are resistant to OsHV-1 as resistance has yet to be evaluated in these oysters. As part of an effort to begin genetic selection for resistance to OsHV-1, 71 families from the Molluscan Broodstock Program, a US West Coast Pacific oyster breeding program, were screened for survival after exposure to OsHV-1 in Tomales Bay. They were also tested in a quarantine laboratory in France where they were exposed to a French OsHV-1 microvariant using a plate assay, with survival recorded from three to seven days post-infection. RESULTS: Significant heritability for survival were found for all time points in the plate assay and in the survival phenotype from a single mortality count in Tomales Bay. Genetic correlations between survival against the French OsHV-1 μvar in the plate assay and the Tomales Bay variant in the field trait were weak or non-significant. CONCLUSIONS: Future breeding efforts will seek to validate the potential of genetic improvement for survival to OsHV-1 through selection using the Molluscan Broodstock Program oysters. The lack of a strong correlation in survival between OsHV-1 variants under this study’s exposure conditions may require independent selection pressure for survival to each variant in order to make simultaneous genetic gains in resistance. Text Pacific oyster PubMed Central (PMC) Pacific BMC Genetics 20 1 |
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Research Article Divilov, Konstantin Schoolfield, Blaine Morga, Benjamin Dégremont, Lionel Burge, Colleen A. Mancilla Cortez, Daniel Friedman, Carolyn S. Fleener, Gary B. Dumbauld, Brett R. Langdon, Chris First evaluation of resistance to both a California OsHV-1 variant and a French OsHV-1 microvariant in Pacific oysters |
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Research Article |
description |
BACKGROUND: Variants of the Ostreid herpesvirus 1 (OsHV-1) cause high losses of Pacific oysters globally, including in Tomales Bay, California, USA. A suite of new variants, the OsHV-1 microvariants (μvars), cause very high mortalities of Pacific oysters in major oyster-growing regions outside of the United States. There are currently no known Pacific oysters in the United States that are resistant to OsHV-1 as resistance has yet to be evaluated in these oysters. As part of an effort to begin genetic selection for resistance to OsHV-1, 71 families from the Molluscan Broodstock Program, a US West Coast Pacific oyster breeding program, were screened for survival after exposure to OsHV-1 in Tomales Bay. They were also tested in a quarantine laboratory in France where they were exposed to a French OsHV-1 microvariant using a plate assay, with survival recorded from three to seven days post-infection. RESULTS: Significant heritability for survival were found for all time points in the plate assay and in the survival phenotype from a single mortality count in Tomales Bay. Genetic correlations between survival against the French OsHV-1 μvar in the plate assay and the Tomales Bay variant in the field trait were weak or non-significant. CONCLUSIONS: Future breeding efforts will seek to validate the potential of genetic improvement for survival to OsHV-1 through selection using the Molluscan Broodstock Program oysters. The lack of a strong correlation in survival between OsHV-1 variants under this study’s exposure conditions may require independent selection pressure for survival to each variant in order to make simultaneous genetic gains in resistance. |
format |
Text |
author |
Divilov, Konstantin Schoolfield, Blaine Morga, Benjamin Dégremont, Lionel Burge, Colleen A. Mancilla Cortez, Daniel Friedman, Carolyn S. Fleener, Gary B. Dumbauld, Brett R. Langdon, Chris |
author_facet |
Divilov, Konstantin Schoolfield, Blaine Morga, Benjamin Dégremont, Lionel Burge, Colleen A. Mancilla Cortez, Daniel Friedman, Carolyn S. Fleener, Gary B. Dumbauld, Brett R. Langdon, Chris |
author_sort |
Divilov, Konstantin |
title |
First evaluation of resistance to both a California OsHV-1 variant and a French OsHV-1 microvariant in Pacific oysters |
title_short |
First evaluation of resistance to both a California OsHV-1 variant and a French OsHV-1 microvariant in Pacific oysters |
title_full |
First evaluation of resistance to both a California OsHV-1 variant and a French OsHV-1 microvariant in Pacific oysters |
title_fullStr |
First evaluation of resistance to both a California OsHV-1 variant and a French OsHV-1 microvariant in Pacific oysters |
title_full_unstemmed |
First evaluation of resistance to both a California OsHV-1 variant and a French OsHV-1 microvariant in Pacific oysters |
title_sort |
first evaluation of resistance to both a california oshv-1 variant and a french oshv-1 microvariant in pacific oysters |
publisher |
BioMed Central |
publishDate |
2019 |
url |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6909534/ http://www.ncbi.nlm.nih.gov/pubmed/31830898 https://doi.org/10.1186/s12863-019-0791-3 |
geographic |
Pacific |
geographic_facet |
Pacific |
genre |
Pacific oyster |
genre_facet |
Pacific oyster |
op_relation |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6909534/ http://www.ncbi.nlm.nih.gov/pubmed/31830898 http://dx.doi.org/10.1186/s12863-019-0791-3 |
op_rights |
© The Author(s). 2019 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
op_rightsnorm |
CC0 PDM CC-BY |
op_doi |
https://doi.org/10.1186/s12863-019-0791-3 |
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BMC Genetics |
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20 |
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1 |
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1766162093047808000 |