Variations in tuberculosis prevalence, Russian Federation: a multivariate approach
OBJECTIVE: To analyse the epidemiological trends of tuberculosis in the Siberian and Far Eastern federal districts, the areas with the highest disease burden in the Russian Federation. METHODS: We applied principal coordinate analysis to study a total of 68 relevant variables on tuberculosis epidemi...
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ftpubmed:oai:pubmedcentral.nih.gov:6802703 2023-05-15T15:54:52+02:00 Variations in tuberculosis prevalence, Russian Federation: a multivariate approach Meshkov, Ivan Petrenko, Tatyana Keiser, Olivia Estill, Janne Revyakina, Olga Felker, Irina Raviglione, Mario C Krasnov, Vladimir Schwartz, Yakov 2019-11-01 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6802703/ https://doi.org/10.2471/BLT.19.229997 en eng World Health Organization http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6802703/ http://dx.doi.org/10.2471/BLT.19.229997 (c) 2019 The authors; licensee World Health Organization. This is an open access article distributed under the terms of the Creative Commons Attribution IGO License (http://creativecommons.org/licenses/by/3.0/igo/legalcode), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. In any reproduction of this article there should not be any suggestion that WHO or this article endorse any specific organization or products. The use of the WHO logo is not permitted. This notice should be preserved along with the article's original URL. CC-BY Research Text 2019 ftpubmed https://doi.org/10.2471/BLT.19.229997 2019-11-03T01:51:27Z OBJECTIVE: To analyse the epidemiological trends of tuberculosis in the Siberian and Far Eastern federal districts, the areas with the highest disease burden in the Russian Federation. METHODS: We applied principal coordinate analysis to study a total of 68 relevant variables on tuberculosis epidemiology, prevention and control. Data on these variables were collected over 2003–2016 in all 21 regions of the Siberian federal district and Far Eastern federal district (total population: 25.5 million) through the federal and departmental reporting system. We identified the regions with a favourable or unfavourable tuberculosis epidemiological profile and ranked them as low or high priority for specific interventions. FINDINGS: The median number of tuberculosis notifications in the regions was 123.3 per 100 000 population (range: 54.5–265.7) in 2003, decreasing to 82.3 per 100 000 (range: 52.9–178.3) in 2016. We found large variations in the tuberculosis epidemiological profile across different regions. The principal coordinate analysis revealed that three aggregated indicators accounted for 55% of the variation. The first coordinate corresponded to tuberculosis prevalence and case notifications in the regions; the second to the severity of the disease among patients; and the third to the percentage of multidrug-resistant tuberculosis among tuberculosis patients. The regions where intervention was most urgently needed were Chukotka Autonomous Okrug, Jewish Autonomous Oblast and Tyva Republic. CONCLUSION: The variability in tuberculosis epidemiology across regions was likely due to differences in the quality of antituberculosis services. Precision in defining necessary interventions, as determined through the principal coordinate analysis approach, can guide focused tuberculosis control efforts. Text Chukotka Chukotka Autonomous Okrug PubMed Central (PMC) Bulletin of the World Health Organization 97 11 737 745A |
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Research Meshkov, Ivan Petrenko, Tatyana Keiser, Olivia Estill, Janne Revyakina, Olga Felker, Irina Raviglione, Mario C Krasnov, Vladimir Schwartz, Yakov Variations in tuberculosis prevalence, Russian Federation: a multivariate approach |
topic_facet |
Research |
description |
OBJECTIVE: To analyse the epidemiological trends of tuberculosis in the Siberian and Far Eastern federal districts, the areas with the highest disease burden in the Russian Federation. METHODS: We applied principal coordinate analysis to study a total of 68 relevant variables on tuberculosis epidemiology, prevention and control. Data on these variables were collected over 2003–2016 in all 21 regions of the Siberian federal district and Far Eastern federal district (total population: 25.5 million) through the federal and departmental reporting system. We identified the regions with a favourable or unfavourable tuberculosis epidemiological profile and ranked them as low or high priority for specific interventions. FINDINGS: The median number of tuberculosis notifications in the regions was 123.3 per 100 000 population (range: 54.5–265.7) in 2003, decreasing to 82.3 per 100 000 (range: 52.9–178.3) in 2016. We found large variations in the tuberculosis epidemiological profile across different regions. The principal coordinate analysis revealed that three aggregated indicators accounted for 55% of the variation. The first coordinate corresponded to tuberculosis prevalence and case notifications in the regions; the second to the severity of the disease among patients; and the third to the percentage of multidrug-resistant tuberculosis among tuberculosis patients. The regions where intervention was most urgently needed were Chukotka Autonomous Okrug, Jewish Autonomous Oblast and Tyva Republic. CONCLUSION: The variability in tuberculosis epidemiology across regions was likely due to differences in the quality of antituberculosis services. Precision in defining necessary interventions, as determined through the principal coordinate analysis approach, can guide focused tuberculosis control efforts. |
format |
Text |
author |
Meshkov, Ivan Petrenko, Tatyana Keiser, Olivia Estill, Janne Revyakina, Olga Felker, Irina Raviglione, Mario C Krasnov, Vladimir Schwartz, Yakov |
author_facet |
Meshkov, Ivan Petrenko, Tatyana Keiser, Olivia Estill, Janne Revyakina, Olga Felker, Irina Raviglione, Mario C Krasnov, Vladimir Schwartz, Yakov |
author_sort |
Meshkov, Ivan |
title |
Variations in tuberculosis prevalence, Russian Federation: a multivariate approach |
title_short |
Variations in tuberculosis prevalence, Russian Federation: a multivariate approach |
title_full |
Variations in tuberculosis prevalence, Russian Federation: a multivariate approach |
title_fullStr |
Variations in tuberculosis prevalence, Russian Federation: a multivariate approach |
title_full_unstemmed |
Variations in tuberculosis prevalence, Russian Federation: a multivariate approach |
title_sort |
variations in tuberculosis prevalence, russian federation: a multivariate approach |
publisher |
World Health Organization |
publishDate |
2019 |
url |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6802703/ https://doi.org/10.2471/BLT.19.229997 |
genre |
Chukotka Chukotka Autonomous Okrug |
genre_facet |
Chukotka Chukotka Autonomous Okrug |
op_relation |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6802703/ http://dx.doi.org/10.2471/BLT.19.229997 |
op_rights |
(c) 2019 The authors; licensee World Health Organization. This is an open access article distributed under the terms of the Creative Commons Attribution IGO License (http://creativecommons.org/licenses/by/3.0/igo/legalcode), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. In any reproduction of this article there should not be any suggestion that WHO or this article endorse any specific organization or products. The use of the WHO logo is not permitted. This notice should be preserved along with the article's original URL. |
op_rightsnorm |
CC-BY |
op_doi |
https://doi.org/10.2471/BLT.19.229997 |
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Bulletin of the World Health Organization |
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97 |
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11 |
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737 |
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745A |
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1766390112171589632 |